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1 |
Material Type: Artigo
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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1Guan, Kun-Liang ; Kim, Joungmok ; Kundu, Mondira ; Viollet, BenoitNature cell biology, 2011-02, Vol.13 (2), p.132-141 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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2 |
Material Type: Artigo
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Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cellsMorrison, Sean J ; Nakada, Daisuke ; Saunders, Thomas LNature (London), 2010-12, Vol.468 (7324), p.653-658 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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3 |
Material Type: Artigo
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DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagyZhao, Yongchao ; Xiong, Xiufang ; Sun, YiMolecular cell, 2011-10, Vol.44 (2), p.304-316 [Periódico revisado por pares]United StatesTexto completo disponível |
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4 |
Material Type: Artigo
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High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stabilityCheung, Lydia W T ; Hennessy, Bryan T ; Li, Jie ; Yu, Shuangxing ; Myers, Andrea P ; Djordjevic, Bojana ; Lu, Yiling ; Stemke-Hale, Katherine ; Dyer, Mary D ; Zhang, Fan ; Ju, Zhenlin ; Cantley, Lewis C ; Scherer, Steven E ; Liang, Han ; Lu, Karen H ; Broaddus, Russell R ; Mills, Gordon BCancer discovery, 2011-07, Vol.1 (2), p.170-185United StatesTexto completo disponível |
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5 |
Material Type: Artigo
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Lysosomal positioning coordinates cellular nutrient responsesSiddiqi, Farah H ; Roberts, Esteban A ; Rubinsztein, David C ; Menzies, Fiona M ; Sarkar, Sovan ; Imarisio, Sara ; O'Kane, Cahir J ; Futter, Marie ; Deretic, Vojo ; Saiki, Shinji ; Jahreiss, Luca ; Korolchuk, Viktor I ; Lichtenberg, MaikeNature cell biology, 2011-04, Vol.13 (4), p.453-460 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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6 |
Material Type: Artigo
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The Lkb1 metabolic sensor maintains haematopoietic stem cell survivalScadden, David T ; Bardeesy, Nabeel ; Gurumurthy, Sushma ; Xie, Stephanie Z ; Alagesan, Brinda ; Kim, Judith ; Yusuf, Rushdia Z ; Saez, Borja ; Tzatsos, Alexandros ; Ozsolak, Fatih ; Milos, Patrice ; Ferrari, Francesco ; Park, Peter J ; Shirihai, Orian SNature (London), 2010-12, Vol.468 (7324), p.659-663 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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7 |
Material Type: Artigo
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Rapamycin passes the torch: a new generation of mTOR inhibitorsBenjamin, Don ; Colombi, Marco ; Moroni, Christoph ; Hall, Michael NNature reviews. Drug discovery, 2011-11, Vol.10 (11), p.868-880 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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8 |
Material Type: Artigo
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The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationMendoza, Michelle C. ; Er, E. Emrah ; Blenis, JohnTrends in biochemical sciences (Amsterdam. Regular ed.), 2011-06, Vol.36 (6), p.320-328 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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9 |
Material Type: Artigo
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The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorderJernigan, Courtney S. ; Goswami, Dharmendra B. ; Austin, Mark C. ; Iyo, Abiye H. ; Chandran, Agata ; Stockmeier, Craig A. ; Karolewicz, BeataProgress in neuro-psychopharmacology & biological psychiatry, 2011-08, Vol.35 (7), p.1774-1779 [Periódico revisado por pares]Amsterdam: Elsevier IncTexto completo disponível |
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10 |
Material Type: Artigo
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Lactobacillus plantarum Promotes Drosophila Systemic Growth by Modulating Hormonal Signals through TOR-Dependent Nutrient SensingStorelli, Gilles ; Defaye, Arnaud ; Erkosar, Berra ; Hols, Pascal ; Royet, Julien ; Leulier, FrançoisCell metabolism, 2011-09, Vol.14 (3), p.403-414 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |