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Material Type: Artigo
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The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection ModelZmurko, Joanna ; Marques, Rafael E ; Schols, Dominique ; Verbeken, Erik ; Kaptein, Suzanne J F ; Neyts, Johan Powers, Ann MPLoS neglected tropical diseases, 2016-05, Vol.10 (5), p.e0004695-e0004695 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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CYP17 inhibitors--abiraterone, C17,20-lyase inhibitors and multi-targeting agentsYin, Lina ; Hu, QingzhongNature reviews. Urology, 2014-01, Vol.11 (1), p.32-42 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null respondersChayama, Kazuaki ; Takahashi, Shoichi ; Toyota, Joji ; Karino, Yoshiyasu ; Ikeda, Kenji ; Ishikawa, Hiroki ; Watanabe, Hideaki ; McPhee, Fiona ; Hughes, Eric ; Kumada, HiromitsuHepatology (Baltimore, Md.), 2012-03, Vol.55 (3), p.742-748 [Periódico revisado por pares]Hoboken: Wiley Subscription Services, Inc., A Wiley CompanyTexto completo disponível |
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Material Type: Artigo
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Angiotensin‐converting enzyme inhibitor works as a scar formation inhibitor by down‐regulating Smad and TGF‐β‐activated kinase 1 (TAK1) pathways in miceTan, Wei‐Qiang ; Fang, Qing‐Qing ; Shen, Xiao Z ; Giani, Jorge F ; Zhao, Tuantuan V ; Shi, Peng ; Zhang, Li‐Yun ; Khan, Zakir ; Li, You ; Li, Liang ; Xu, Ji‐Hua ; Bernstein, Ellen A ; Bernstein, Kenneth EBritish journal of pharmacology, 2018-11, Vol.175 (22), p.4239-4252 [Periódico revisado por pares]England: John Wiley and Sons IncTexto completo disponível |
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Material Type: Artigo
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Cancer Risk and Use of Protease Inhibitor or Nonnucleoside Reverse Transcriptase Inhibitor–Based Combination Antiretroviral Therapy: The D: A: D StudyBruyand, Mathias ; Ryom, Lene ; Shepherd, Leah ; Fatkenheuer, Gerd ; Grulich, Andrew ; Reiss, Peter ; de Wit, Stéphane ; d´Arminio Monforte, Antonella ; Furrer, Hansjakob ; Pradier, Christian ; Lundgren, Jens ; Sabin, CarolineJournal of acquired immune deficiency syndromes (1999), 2015-04, Vol.68 (5), p.568-577 [Periódico revisado por pares]United States: Copyright Wolters Kluwer Health, Inc. All rights reservedTexto completo disponível |
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Material Type: Artigo
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Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic SyndromeLegendre, C.M ; Licht, C ; Muus, P ; Greenbaum, L.A ; Babu, S ; Bedrosian, C ; Bingham, C ; Cohen, D.J ; Delmas, Y ; Douglas, K ; Eitner, F ; Feldkamp, T ; Fouque, D ; Furman, R.R ; Gaber, O ; Herthelius, M ; Hourmant, M ; Karpman, D ; Lebranchu, Y ; Mariat, C ; Menne, J ; Moulin, B ; Nürnberger, J ; Ogawa, M ; Remuzzi, G ; Richard, T ; Sberro-Soussan, R ; Severino, B ; Sheerin, N.S ; Trivelli, A ; Zimmerhackl, L.B ; Goodship, T ; Loirat, CThe New England journal of medicine, 2013-06, Vol.368 (23), p.2169-2181 [Periódico revisado por pares]Waltham, MA: Massachusetts Medical SocietyTexto completo disponível |
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Material Type: Artigo
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Weight gain among treatment‐naïve persons with HIV starting integrase inhibitors compared to non‐nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in the United States and CanadaBourgi, Kassem ; Jenkins, Cathy A ; Rebeiro, Peter F ; Palella, Frank ; Moore, Richard D ; Altoff, Keri N ; Gill, John ; Rabkin, Charles S ; Gange, Stephen J ; Horberg, Michael A ; Margolick, Joseph ; Li, Jun ; Wong, Cherise ; Willig, Amanda ; Lima, Viviane D ; Crane, Heidi ; Thorne, Jennifer ; Silverberg, Michael ; Kirk, Gregory ; Mathews, William C ; Sterling, Timothy R ; Lake, Jordan ; Koethe, John RJournal of the International AIDS Society, 2020-04, Vol.23 (4), p.e25484-n/a [Periódico revisado por pares]Switzerland: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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Efficacy and Safety of Patritumab Deruxtecan (HER3-DXd) in EGFR Inhibitor-Resistant, EGFR -Mutated Non-Small Cell Lung CancerJänne, Pasi A ; Baik, Christina ; Su, Wu-Chou ; Johnson, Melissa L ; Hayashi, Hidetoshi ; Nishio, Makoto ; Kim, Dong-Wan ; Koczywas, Marianna ; Gold, Kathryn A ; Steuer, Conor E ; Murakami, Haruyasu ; Yang, James Chih-Hsin ; Kim, Sang-We ; Vigliotti, Michele ; Shi, Rong ; Qi, Zhenhao ; Qiu, Yang ; Zhao, Lihui ; Sternberg, David ; Yu, Channing ; Yu, Helena ACancer discovery, 2022-01, Vol.12 (1), p.74-89United States: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Transcriptome analysis of proton pump inhibitor–responsive esophageal eosinophilia reveals proton pump inhibitor–reversible allergic inflammationWen, Ting, PhD ; Dellon, Evan S., MD ; Moawad, Fouad J., MD ; Furuta, Glenn T., MD ; Aceves, Seema S., MD, PhD ; Rothenberg, Marc E., MD, PhDJournal of allergy and clinical immunology, 2015-01, Vol.135 (1), p.187-197.e4 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interactionKaptein, Suzanne J F ; Goethals, Olivia ; Kiemel, Dominik ; Marchand, Arnaud ; Kesteleyn, Bart ; Bonfanti, Jean-François ; Bardiot, Dorothée ; Stoops, Bart ; Jonckers, Tim H M ; Dallmeier, Kai ; Geluykens, Peggy ; Thys, Kim ; Crabbe, Marjolein ; Chatel-Chaix, Laurent ; Münster, Max ; Querat, Gilles ; Touret, Franck ; de Lamballerie, Xavier ; Raboisson, Pierre ; Simmen, Kenny ; Chaltin, Patrick ; Bartenschlager, Ralf ; Van Loock, Marnix ; Neyts, JohanNature (London), 2021-10, Vol.598 (7881), p.504-509 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |