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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

Herman, Sarah E.M. ; Gordon, Amber L. ; Hertlein, Erin ; Ramanunni, Asha ; Zhang, Xiaoli ; Jaglowski, Samantha ; Flynn, Joseph ; Jones, Jeffrey ; Blum, Kristie A. ; Buggy, Joseph J. ; Hamdy, Ahmed ; Johnson, Amy J. ; Byrd, John C.

Blood, 2011-06, Vol.117 (23), p.6287-6296 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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2
N 6 -methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications
N 6 -methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications
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N 6 -methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications

Wang, Yang ; Li, Yue ; Yue, Minghui ; Wang, Jun ; Kumar, Sandeep ; Wechsler-Reya, Robert J ; Zhang, Zhaolei ; Ogawa, Yuya ; Kellis, Manolis ; Duester, Gregg ; Zhao, Jing Crystal

Nature neuroscience, 2018-02, Vol.21 (2), p.195-206 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation
APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation
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APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation

Cescon, David W ; Haibe-Kains, Benjamin ; Mak, Tak W

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (9), p.2841-2846 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma
Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma
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Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma

Shenoy, Niraj ; Bhagat, Tushar D ; Cheville, John ; Lohse, Christine ; Bhattacharyya, Sanchari ; Tischer, Alexander ; Machha, Venkata ; Gordon-Mitchell, Shanisha ; Choudhary, Gaurav ; Wong, Li-Fan ; Gross, LouAnn ; Ressigue, Emily ; Leibovich, Bradley ; Boorjian, Stephen A ; Steidl, Ulrich ; Wu, Xiaosheng ; Pradhan, Kith ; Gartrell, Benjamin ; Agarwal, Beamon ; Pagliaro, Lance ; Suzuki, Masako ; Greally, John M ; Rakheja, Dinesh ; Thompson, R Houston ; Susztak, Katalin ; Witzig, Thomas ; Zou, Yiyu ; Verma, Amit

The Journal of clinical investigation, 2019-04, Vol.129 (4), p.1612-1625 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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5
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Gay, Carl M. ; Stewart, C. Allison ; Park, Elizabeth M. ; Diao, Lixia ; Groves, Sarah M. ; Heeke, Simon ; Nabet, Barzin Y. ; Fujimoto, Junya ; Solis, Luisa M. ; Lu, Wei ; Xi, Yuanxin ; Cardnell, Robert J. ; Wang, Qi ; Fabbri, Giulia ; Cargill, Kasey R. ; Vokes, Natalie I. ; Ramkumar, Kavya ; Zhang, Bingnan ; Della Corte, Carminia M. ; Robson, Paul ; Swisher, Stephen G. ; Roth, Jack A. ; Glisson, Bonnie S. ; Shames, David S. ; Wistuba, Ignacio I. ; Wang, Jing ; Quaranta, Vito ; Minna, John ; Heymach, John V. ; Byers, Lauren Averett

Cancer cell, 2021-03, Vol.39 (3), p.346-360.e7 [Periódico revisado por pares]

United States: Elsevier Inc

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6
The emerging roles of forkhead box (Fox) proteins in cancer
The emerging roles of forkhead box (Fox) proteins in cancer
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The emerging roles of forkhead box (Fox) proteins in cancer

Lam, Eric W. -F ; Myatt, Stephen S

Nature reviews. Cancer, 2007-11, Vol.7 (11), p.847-859 [Periódico revisado por pares]

England: Nature Publishing Group

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7
CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells
CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells
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CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

Henri, Sandrine ; Poulin, Lionel Franz ; Tamoutounour, Samira ; Ardouin, Laurence ; Guilliams, Martin ; de Bovis, Béatrice ; Devilard, Elisabeth ; Viret, Christophe ; Azukizawa, Hiroaki ; Kissenpfennig, Adrien ; Malissen, Bernard

The Journal of experimental medicine, 2010-01, Vol.207 (1), p.189-206 [Periódico revisado por pares]

United States: Rockefeller University Press

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8
Enhancer redundancy provides phenotypic robustness in mammalian development
Enhancer redundancy provides phenotypic robustness in mammalian development
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Enhancer redundancy provides phenotypic robustness in mammalian development

Osterwalder, Marco ; Barozzi, Iros ; Tissières, Virginie ; Fukuda-Yuzawa, Yoko ; Mannion, Brandon J ; Afzal, Sarah Y ; Lee, Elizabeth A ; Zhu, Yiwen ; Plajzer-Frick, Ingrid ; Pickle, Catherine S ; Kato, Momoe ; Garvin, Tyler H ; Pham, Quan T ; Harrington, Anne N ; Akiyama, Jennifer A ; Afzal, Veena ; Lopez-Rios, Javier ; Dickel, Diane E ; Visel, Axel ; Pennacchio, Len A

Nature (London), 2018-02, Vol.554 (7691), p.239-243 [Periódico revisado por pares]

England: Nature Publishing Group

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9
Circular RNAs function as ceRNAs to regulate and control human cancer progression
Circular RNAs function as ceRNAs to regulate and control human cancer progression
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Circular RNAs function as ceRNAs to regulate and control human cancer progression

Zhong, Yaxian ; Du, Yajun ; Yang, Xue ; Mo, Yongzhen ; Fan, Chunmei ; Xiong, Fang ; Ren, Daixi ; Ye, Xin ; Li, Chunwei ; Wang, Yumin ; Wei, Fang ; Guo, Can ; Wu, Xu ; Li, Xiaoling ; Li, Yong ; Li, Guiyuan ; Zeng, Zhaoyang ; Xiong, Wei

Molecular cancer, 2018-04, Vol.17 (1), p.79-11, Article 79 [Periódico revisado por pares]

England: BioMed Central Ltd

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10
Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network
Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network
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Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network

Fish, Jason E ; Cantu Gutierrez, Manuel ; Dang, Lan T ; Khyzha, Nadiya ; Chen, Zhiqi ; Veitch, Shawn ; Cheng, Henry S ; Khor, Melvin ; Antounians, Lina ; Njock, Makon-Sébastien ; Boudreau, Emilie ; Herman, Alexander M ; Rhyner, Alexander M ; Ruiz, Oscar E ; Eisenhoffer, George T ; Medina-Rivera, Alejandra ; Wilson, Michael D ; Wythe, Joshua D

Development (Cambridge), 2017-07, Vol.144 (13), p.2428-2444 [Periódico revisado por pares]

England: The Company of Biologists Ltd

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