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1
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
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Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

Gallagher, C S ; Mäkinen, N ; Harris, H R ; Rahmioglu, N ; Uimari, O ; Cook, J P ; Shigesi, N ; Ferreira, T ; Velez-Edwards, D R ; Edwards, T L ; Mortlock, S ; Ruhioglu, Z ; Day, F ; Becker, C M ; Karhunen, V ; Martikainen, H ; Järvelin, M-R ; Cantor, R M ; Ridker, P M ; Terry, K L ; Buring, J E ; Gordon, S D ; Medland, S E ; Montgomery, G W ; Nyholt, D R ; Hinds, D A ; Tung, J Y ; Perry, J R B ; Lind, P A ; Painter, J N ; Martin, N G ; Morris, A P ; Chasman, D I ; Missmer, S A ; Zondervan, K T ; Morton, C C

Nature communications, 2019-10, Vol.10 (1), p.4857-11, Article 4857 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids
Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids
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Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids

George, Jitu Wilson ; Fan, Huihui ; Johnson, Benjamin ; Carpenter, Tyler James ; Foy, Kelly Katherine ; Chatterjee, Anindita ; Patterson, Amanda Lynn ; Koeman, Julie ; Adams, Marie ; Madaj, Zachary Brian ; Chesla, David ; Marsh, Erica Elizabeth ; Triche, Timothy Junius ; Shen, Hui ; Teixeira, Jose Manuel

Cell reports (Cambridge), 2019-12, Vol.29 (12), p.4069-4085.e6 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Obesity and risk of female reproductive conditions: A Mendelian randomisation study
Obesity and risk of female reproductive conditions: A Mendelian randomisation study
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Obesity and risk of female reproductive conditions: A Mendelian randomisation study

Venkatesh, Samvida S ; Ferreira, Teresa ; Benonisdottir, Stefania ; Rahmioglu, Nilufer ; Becker, Christian M ; Granne, Ingrid ; Zondervan, Krina T ; Holmes, Michael V ; Lindgren, Cecilia M ; Wittemans, Laura B L Stock, Sarah J.

PLoS medicine, 2022-02, Vol.19 (2), p.e1003679-e1003679 [Periódico revisado por pares]

United States: Public Library of Science

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4
Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tube
Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tube
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Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tube

Dinh, Huy Q. ; Lin, Xianzhi ; Abbasi, Forough ; Nameki, Robbin ; Haro, Marcela ; Olingy, Claire E. ; Chang, Heidi ; Hernandez, Lourdes ; Gayther, Simon A. ; Wright, Kelly N. ; Aspuria, Paul-Joseph ; Karlan, Beth Y. ; Corona, Rosario I. ; Li, Andrew ; Rimel, B.J. ; Siedhoff, Matthew T. ; Medeiros, Fabiola ; Lawrenson, Kate

Cell reports (Cambridge), 2021-04, Vol.35 (2), p.108978-108978, Article 108978 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19
Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19
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Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

Park, Min Ju ; Shen, Hailian ; Spaeth, Jason M. ; Tolvanen, Jaana H. ; Failor, Courtney ; Knudtson, Jennifer F. ; McLaughlin, Jessica ; Halder, Sunil K. ; Yang, Qiwei ; Bulun, Serdar E. ; Al-Hendy, Ayman ; Schenken, Robert S. ; Aaltonen, Lauri A. ; Boyer, Thomas G.

The Journal of biological chemistry, 2018-03, Vol.293 (13), p.4870-4882 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Altered chromatin landscape and enhancer engagement underlie transcriptional dysregulation in MED12 mutant uterine leiomyomas
Altered chromatin landscape and enhancer engagement underlie transcriptional dysregulation in MED12 mutant uterine leiomyomas
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Altered chromatin landscape and enhancer engagement underlie transcriptional dysregulation in MED12 mutant uterine leiomyomas

Moyo, Mthabisi B ; Parker, J Brandon ; Chakravarti, Debabrata

Nature communications, 2020-02, Vol.11 (1), p.1019-16, Article 1019 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Med12 gain-of-function mutation causes leiomyomas and genomic instability
Med12 gain-of-function mutation causes leiomyomas and genomic instability
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Med12 gain-of-function mutation causes leiomyomas and genomic instability

Mittal, Priya ; Shin, Yong-Hyun ; Yatsenko, Svetlana A ; Castro, Carlos A ; Surti, Urvashi ; Rajkovic, Aleksandar

The Journal of clinical investigation, 2015-08, Vol.125 (8), p.3280-3284 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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8
A differential diagnosis between uterine leiomyoma and leiomyosarcoma using transcriptome analysis
A differential diagnosis between uterine leiomyoma and leiomyosarcoma using transcriptome analysis
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A differential diagnosis between uterine leiomyoma and leiomyosarcoma using transcriptome analysis

Kim, Kidong ; Kim, Sarah ; Ahn, TaeJin ; Kim, Hyojin ; Shin, So-Jin ; Choi, Chel Hun ; Park, Sungmin ; Kim, Yong-Beom ; No, Jae Hong ; Suh, Dong Hoon

BMC cancer, 2023-12, Vol.23 (1), p.1215-11, Article 1215 [Periódico revisado por pares]

England: BioMed Central Ltd

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9
miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis
miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis
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miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis

Chuang, Tsai-Der ; Khorram, Omid Li, Jun

PloS one, 2014-04, Vol.9 (4), p.e95370-e95370 [Periódico revisado por pares]

United States: Public Library of Science

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10
Uterine Leiomyoma-Linked MED12 Mutations Disrupt Mediator-Associated CDK Activity
Uterine Leiomyoma-Linked MED12 Mutations Disrupt Mediator-Associated CDK Activity
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Uterine Leiomyoma-Linked MED12 Mutations Disrupt Mediator-Associated CDK Activity

Turunen, Mikko ; Spaeth, Jason M. ; Keskitalo, Salla ; Park, Min Ju ; Kivioja, Teemu ; Clark, Alison D. ; Mäkinen, Netta ; Gao, Fangjian ; Palin, Kimmo ; Nurkkala, Helka ; Vähärautio, Anna ; Aavikko, Mervi ; Kämpjärvi, Kati ; Vahteristo, Pia ; Kim, Chongwoo A. ; Aaltonen, Lauri A. ; Varjosalo, Markku ; Taipale, Jussi ; Boyer, Thomas G.

Cell reports (Cambridge), 2014-05, Vol.7 (3), p.654-660 [Periódico revisado por pares]

United States: Elsevier Inc

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