skip to main content
Idioma:
Resultados 1 2 3 4 5 next page
Refinado por: assunto: Chemistry, Medicinal remover American Chemical Society Journals remover assunto: General Aspects remover
Result Number Material Type Add to My Shelf Action Record Details and Options
1
Medicinal Chemistry of Combretastatin A4:  Present and Future Directions
Medicinal Chemistry of Combretastatin A4:  Present and Future Directions
Material Type:
Artigo 		Adicionar ao Meu Espaço

Medicinal Chemistry of Combretastatin A4:  Present and Future Directions

Tron, Gian Cesare ; Pirali, Tracey ; Sorba, Giovanni ; Pagliai, Francesca ; Busacca, Sara ; Genazzani, Armando A

Journal of medicinal chemistry, 2006-06, Vol.49 (11), p.3033-3044 [Periódico revisado por pares]

Washington, DC: American Chemical Society

Texto completo disponível

Citações Citado por
2
Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure−Activity Relationship and Mechanistic Insight
Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure−Activity Relationship and Mechanistic Insight
Material Type:
Artigo 		Adicionar ao Meu Espaço

Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure−Activity Relationship and Mechanistic Insight

Lamoral-Theys, Delphine ; Andolfi, Anna ; Van Goietsenoven, Gwendoline ; Cimmino, Alessio ; Le Calvé, Benjamin ; Wauthoz, Nathalie ; Mégalizzi, Véronique ; Gras, Thierry ; Bruyère, Céline ; Dubois, Jacques ; Mathieu, Véronique ; Kornienko, Alexander ; Kiss, Robert ; Evidente, Antonio

Journal of medicinal chemistry, 2009-10, Vol.52 (20), p.6244-6256 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

Texto completo disponível

Citações Citado por
3
Selectively Nonselective Kinase Inhibition: Striking the Right Balance
Selectively Nonselective Kinase Inhibition: Striking the Right Balance
Material Type:
Artigo 		Adicionar ao Meu Espaço

Selectively Nonselective Kinase Inhibition: Striking the Right Balance

Morphy, Richard

Journal of medicinal chemistry, 2010-02, Vol.53 (4), p.1413-1437 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

Texto completo disponível

Citações Citado por
4
4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1
4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1
Material Type:
Artigo 		Adicionar ao Meu Espaço

4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1

Menear, Keith A ; Adcock, Claire ; Boulter, Robert ; Cockcroft, Xiao-ling ; Copsey, Louise ; Cranston, Aaron ; Dillon, Krystyna J ; Drzewiecki, Jan ; Garman, Sheila ; Gomez, Sylvie ; Javaid, Hashim ; Kerrigan, Frank ; Knights, Charlotte ; Lau, Alan ; Loh, Vincent M ; Matthews, Ian T. W ; Moore, Stephen ; O’Connor, Mark J ; Smith, Graeme C. M ; Martin, Niall M. B

Journal of medicinal chemistry, 2008-10, Vol.51 (20), p.6581-6591 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

Texto completo disponível

Citações Citado por
5
Basis for Design and Development of Platinum(IV) Anticancer Complexes
Basis for Design and Development of Platinum(IV) Anticancer Complexes
Material Type:
Artigo 		Adicionar ao Meu Espaço

Basis for Design and Development of Platinum(IV) Anticancer Complexes

Hall, Matthew D ; Mellor, Howard R ; Callaghan, Richard ; Hambley, Trevor W

Journal of medicinal chemistry, 2007-07, Vol.50 (15), p.3403-3411 [Periódico revisado por pares]

Washington, DC: American Chemical Society

Texto completo disponível

Citações Citado por
6
4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer
4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer
Material Type:
Artigo 		Adicionar ao Meu Espaço

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Brough, Paul A ; Aherne, Wynne ; Barril, Xavier ; Borgognoni, Jenifer ; Boxall, Kathy ; Cansfield, Julie E ; Cheung, Kwai-Ming J ; Collins, Ian ; Davies, Nicholas G. M ; Drysdale, Martin J ; Dymock, Brian ; Eccles, Suzanne A ; Finch, Harry ; Fink, Alexandra ; Hayes, Angela ; Howes, Robert ; Hubbard, Roderick E ; James, Karen ; Jordan, Allan M ; Lockie, Andrea ; Martins, Vanessa ; Massey, Andrew ; Matthews, Thomas P ; McDonald, Edward ; Northfield, Christopher J ; Pearl, Laurence H ; Prodromou, Chrisostomos ; Ray, Stuart ; Raynaud, Florence I ; Roughley, Stephen D ; Sharp, Swee Y ; Surgenor, Allan ; Walmsley, D. Lee ; Webb, Paul ; Wood, Mike ; Workman, Paul ; Wright, Lisa

Journal of medicinal chemistry, 2008-01, Vol.51 (2), p.196-218 [Periódico revisado por pares]

Washington, DC: American Chemical Society

Texto completo disponível

Citações Citado por
7
Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction
Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction
Material Type:
Artigo 		Adicionar ao Meu Espaço

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

Ding, Ke ; Lu, Yipin ; Nikolovska-Coleska, Zaneta ; Wang, Guoping ; Qiu, Su ; Shangary, Sanjeev ; Gao, Wei ; Qin, Dongguang ; Stuckey, Jeanne ; Krajewski, Krzysztof ; Roller, Peter P ; Wang, Shaomeng

Journal of medicinal chemistry, 2006-06, Vol.49 (12), p.3432-3435 [Periódico revisado por pares]

Washington, DC: American Chemical Society

Texto completo disponível

Citações Citado por
8
Procaspase-3 Activation as an Anti-Cancer Strategy: Structure−Activity Relationship of Procaspase-Activating Compound 1 (PAC-1) and Its Cellular Co-Localization with Caspase-3
Procaspase-3 Activation as an Anti-Cancer Strategy: Structure−Activity Relationship of Procaspase-Activating Compound 1 (PAC-1) and Its Cellular Co-Localization with Caspase-3
Material Type:
Artigo 		Adicionar ao Meu Espaço

Procaspase-3 Activation as an Anti-Cancer Strategy: Structure−Activity Relationship of Procaspase-Activating Compound 1 (PAC-1) and Its Cellular Co-Localization with Caspase-3

Peterson, Quinn P. ; Hsu, Danny C. ; Goode, David R. ; Novotny, Chris J. ; Totten, Ryan K. ; Hergenrother, Paul J.

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5721-5731 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

Texto completo disponível

Citações Citado por
9
Identification of N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design
Identification of N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design
Material Type:
Artigo 		Adicionar ao Meu Espaço

Identification of N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design

Wyatt, Paul G ; Woodhead, Andrew J ; Berdini, Valerio ; Boulstridge, John A ; Carr, Maria G ; Cross, David M ; Davis, Deborah J ; Devine, Lindsay A ; Early, Theresa R ; Feltell, Ruth E ; Lewis, E. Jonathan ; McMenamin, Rachel L ; Navarro, Eva F ; O’Brien, Michael A ; O’Reilly, Marc ; Reule, Matthias ; Saxty, Gordon ; Seavers, Lisa C. A ; Smith, Donna-Michelle ; Squires, Matt S ; Trewartha, Gary ; Walker, Margaret T ; Woolford, Alison J.-A

Journal of medicinal chemistry, 2008-08, Vol.51 (16), p.4986-4999 [Periódico revisado por pares]

Washington, DC: American Chemical Society

Texto completo disponível

Citações Citado por
10
Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships
Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships
Material Type:
Artigo 		Adicionar ao Meu Espaço

Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships

Lu, Yan ; Li, Chien-Ming ; Wang, Zhao ; Ross, Charles R ; Chen, Jianjun ; Dalton, James T ; Li, Wei ; Miller, Duane D

Journal of medicinal chemistry, 2009-03, Vol.52 (6), p.1701-1711 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

Texto completo disponível

Citações Citado por
Resultados 1 2 3 4 5 next page

Personalize Seus Resultados

  1. Editar

Refine Search Results

Expandir Meus Resultados

  1.   

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.