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1,2,3-Triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: Potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones
1,2,3-Triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: Potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones
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1,2,3-Triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: Potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones

da Cruz, Eduardo H.G. ; Hussene, Caio M.B. ; Dias, Gleiston G. ; Diogo, Emilay B.T. ; de Melo, Isadora M.M. ; Rodrigues, Bernardo L. ; da Silva, Mauro G. ; Valença, Wagner O. ; Camara, Celso A. ; de Oliveira, Ronaldo N. ; de Paiva, Yen G. ; Goulart, Marilia O.F. ; Cavalcanti, Bruno C. ; Pessoa, Claudia ; da Silva Júnior, Eufrânio N.

Bioorganic & medicinal chemistry, 2014-03, Vol.22 (5), p.1608-1619 [Periódico revisado por pares]

England: Elsevier Ltd

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2
3-Arylamino and 3-Alkoxy-nor-β-lapachone Derivatives: Synthesis and Cytotoxicity against Cancer Cell Lines
3-Arylamino and 3-Alkoxy-nor-β-lapachone Derivatives: Synthesis and Cytotoxicity against Cancer Cell Lines
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3-Arylamino and 3-Alkoxy-nor-β-lapachone Derivatives: Synthesis and Cytotoxicity against Cancer Cell Lines

da Silva Júnior, Eufrânio N ; de Deus, Clara F ; Cavalcanti, Bruno C ; Pessoa, Cláudia ; Costa-Lotufo, Letícia V ; Montenegro, Raquel C ; de Moraes, Manoel O ; Pinto, Maria do Carmo F. R ; de Simone, Carlos A ; Ferreira, Vitor F ; Goulart, Marilia O. F ; Andrade, Carlos Kleber Z ; Pinto, Antônio V

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.504-508 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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3
Hybrid compounds with two redox centres: Modular synthesis of chalcogen-containing lapachones and studies on their antitumor activity
Hybrid compounds with two redox centres: Modular synthesis of chalcogen-containing lapachones and studies on their antitumor activity
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Hybrid compounds with two redox centres: Modular synthesis of chalcogen-containing lapachones and studies on their antitumor activity

Vieira, André A. ; Brandão, Igor R. ; Valença, Wagner O. ; de Simone, Carlos A. ; Cavalcanti, Bruno C. ; Pessoa, Claudia ; Carneiro, Teiliane R. ; Braga, Antonio L. ; da Silva, Eufrânio N.

European journal of medicinal chemistry, 2015-08, Vol.101, p.254-265 [Periódico revisado por pares]

France: Elsevier Masson SAS

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4
On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells
On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells
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On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells

Gontijo, Talita B. ; de Freitas, Rossimiriam P. ; Emery, Flavio S. ; Pedrosa, Leandro F. ; Vieira Neto, José B. ; Cavalcanti, Bruno C. ; Pessoa, Claudia ; King, Aaron ; de Moliner, Fabio ; Vendrell, Marc ; da Silva Júnior, Eufrânio N.

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (18), p.4446-4456 [Periódico revisado por pares]

England: Elsevier Ltd

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5
Pterocarpanquinones, aza-pterocarpanquinone and derivatives: Synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis
Pterocarpanquinones, aza-pterocarpanquinone and derivatives: Synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis
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Pterocarpanquinones, aza-pterocarpanquinone and derivatives: Synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis

Buarque, Camilla D. ; Militão, Gardenia C.G. ; Lima, Daisy J.B. ; Costa-Lotufo, Leticia V. ; Pessoa, Cláudia ; de Moraes, Manoel Odorico ; Cunha-Junior, Edézio Ferreira ; Torres-Santos, Eduardo Caio ; Netto, Chaquip D. ; Costa, Paulo R.R.

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (22), p.6885-6891 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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6
Quinonoid compounds via reactions of lawsone and 2-aminonaphthoquinone with α-bromonitroalkenes and nitroallylic acetates: Structural diversity by C-ring modification and cytotoxic evaluation against cancer cells
Quinonoid compounds via reactions of lawsone and 2-aminonaphthoquinone with α-bromonitroalkenes and nitroallylic acetates: Structural diversity by C-ring modification and cytotoxic evaluation against cancer cells
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Quinonoid compounds via reactions of lawsone and 2-aminonaphthoquinone with α-bromonitroalkenes and nitroallylic acetates: Structural diversity by C-ring modification and cytotoxic evaluation against cancer cells

Baiju, Thekke V. ; Almeida, Renata G. ; Sivanandan, Sudheesh T. ; de Simone, Carlos A. ; Brito, Lucas M. ; Cavalcanti, Bruno C. ; Pessoa, Claudia ; Namboothiri, Irishi N.N. ; da Silva Júnior, Eufrânio N.

European journal of medicinal chemistry, 2018-05, Vol.151, p.686-704 [Periódico revisado por pares]

France: Elsevier Masson SAS

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7
Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights
Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights
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Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights

da Cruz, Eduardo H.G. ; Silvers, Molly A. ; Jardim, Guilherme A.M. ; Resende, Jarbas M. ; Cavalcanti, Bruno C. ; Bomfim, Igor S. ; Pessoa, Claudia ; de Simone, Carlos A. ; Botteselle, Giancarlo V. ; Braga, Antonio L. ; Nair, Divya K. ; Namboothiri, Irishi N.N. ; Boothman, David A. ; da Silva Júnior, Eufrânio N.

European journal of medicinal chemistry, 2016-10, Vol.122, p.1-16 [Periódico revisado por pares]

France: Elsevier Masson SAS

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8
Synthesis and potent antitumor activity of new arylamino derivatives of nor-β-lapachone and nor-α-lapachone
Synthesis and potent antitumor activity of new arylamino derivatives of nor-β-lapachone and nor-α-lapachone
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Synthesis and potent antitumor activity of new arylamino derivatives of nor-β-lapachone and nor-α-lapachone

da Silva Júnior, Eufrânio N. ; de Souza, Maria Cecília B.V. ; Pinto, Antônio V. ; Pinto, Maria do Carmo F.R. ; Goulart, Marilia O.F. ; Barros, Francisco W.A. ; Pessoa, Claudia ; Costa-Lotufo, Letícia V. ; Montenegro, Raquel C. ; de Moraes, Manoel O. ; Ferreira, Vitor F.

Bioorganic & medicinal chemistry, 2007-11, Vol.15 (22), p.7035-7041 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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