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SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M PAMs

Chopko, Trevor C ; Han, Changho ; Gregro, Alison R ; Engers, Darren W ; Felts, Andrew S ; Poslusney, Mike S ; Bollinger, Katrina A ; Morrison, Ryan D ; Bubser, Michael ; Lamsal, Atin ; Luscombe, Vincent B ; Cho, Hyekyung P ; Schnetz-Boutaud, Nathalie C ; Rodriguez, Alice L ; Chang, Sichen ; Daniels, J Scott ; Stec, Donald F ; Niswender, Colleen M ; Jones, Carrie K ; Wood, Michael R ; Wood, Michael W ; Duggan, Mark E ; Brandon, Nicholas J ; Conn, P Jeffrey ; Bridges, Thomas M ; Lindsley, Craig W ; Melancon, Bruce J

Bioorganic & medicinal chemistry letters, 15 August 2019, Vol.29(16), pp.2224-2228 [Periódico revisado por pares]

MEDLINE/PubMed (U.S. National Library of Medicine)

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SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M.sub.4 PAMs.(Report)

Chopko, Trevor C. ; Han, Changho ; Gregro, Alison R. ; Engers, Darren W. ; Felts, Andrew S. ; Poslusney, Mike S. ; Bollinger, Katrina A. ; Morrison, Ryan D. ; Bubser, Michael ; Lamsal, Atin ; Luscombe, Vincent B. ; Cho, Hyekyung P. ; Schnetz-Boutaud, Nathalie C. ; Rodriguez, Alice L. ; Chang, Sichen ; Daniels, J. Scott ; Stec, Donald F. ; Niswender, Colleen M. ; Jones, Carrie K. ; Wood, Michael R. ; Wood, Michael W. ; Duggan, Mark E. ; Brandon, Nicholas J. ; Conn, P. Jeffrey ; Bridges, Thomas M. ; Lindsley, Craig W. ; Melancon, Bruce J.

Bioorganic & Medicinal Chemistry Letters, August 15, 2019, Vol.29(16), p.2224 [Periódico revisado por pares]

Cengage Learning, Inc.

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