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1 |
Material Type: Artigo
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A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cellsSane, Komal M ; Mynderse, Michelle ; Lalonde, Daniel T ; Dean, Ivory S ; Wojtkowiak, Jonathan W ; Fouad, Farid ; Borch, Richard F ; Reiners, Jr, John J ; Gibbs, Richard A ; Mattingly, Raymond RThe Journal of pharmacology and experimental therapeutics, 2010-04, Vol.333 (1), p.23-33 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Non-Peptidic Prenyltransferase Inhibitors: Diverse Structural Classes and Surprising Anti-Cancer MechanismsGibbs, R A ; Zahn, T J ; Sebolt-Leopold, J SCurrent medicinal chemistry, 2001-10, Vol.8 (12), p.1437-1465 [Periódico revisado por pares]United Arab Emirates: Bentham Science Publishers LtdTexto completo disponível |
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Material Type: Artigo
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Novel Farnesol and Geranylgeraniol Analogues: A Potential New Class of Anticancer Agents Directed against Protein PrenylationGibbs, Barbara S ; Zahn, Todd J ; Mu, YongQi ; Sebolt-Leopold, Judith S ; Gibbs, Richard AJournal of medicinal chemistry, 1999-09, Vol.42 (19), p.3800-3808 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencingSTARK, Mitchell S ; WOODS, Susan L ; ELLIS, Jonathan J ; REID, Jeffrey ; ZISMANN, Victoria ; TYAGI, Sonika ; MUZNY, Donna ; NEWSHAM, Irene ; YUANQING WU ; PALMER, Jane M ; POLLAK, Thomas ; YOUNGKIN, David ; GARTSIDE, Michael G ; BROOKS, Bradford R ; LANAGAN, Catherine ; SCHMIDT, Christopher W ; KOBE, Bostjan ; MACKEIGAN, Jeffrey P ; YIN, Hongwei ; BROWN, Kevin M ; GIBBS, Richard ; TRENT, Jeffrey ; HAYWARD, Nicholas K ; BONAZZI, Vanessa F ; DUTTON-REGESTER, Ken ; AOUDE, Lauren G ; CHOW, Donald ; SEREDUK, Chris ; NIEMI, Natalie M ; TANG, NanyunNature genetics, 2012-02, Vol.44 (2), p.165-169 [Periódico revisado por pares]New York, NY: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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C-Terminal Modifications of Histidyl-N-benzylglycinamides To Give Improved Inhibition of Ras Farnesyltransferase, Cellular Activity, and Anticancer Activity in MiceMcNamara, Dennis J ; Dobrusin, Ellen ; Leonard, Daniele M ; Shuler, Kevon R ; Kaltenbronn, James S ; Quin, John ; Bur, Scott ; Thomas, Charles E ; Doherty, Annette M ; Scholten, Jeffrey D ; Zimmerman, Karen K ; Gibbs, Barbara S ; Gowan, Richard C ; Latash, Michael P ; Leopold, Wilbur R ; Przybranowski, Sally A ; Sebolt-Leopold, Judith SJournal of medicinal chemistry, 1997-10, Vol.40 (21), p.3319-3322 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Effects of oncostatin M and tamoxifen on human melanoma cellsGibbs, P ; Chen, Q ; Robinson, W AMelanoma research, 1998-06, Vol.8 (3), p.221-226 [Periódico revisado por pares]EnglandTexto completo disponível |
7 |
Material Type: Artigo
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DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinomaZhang, Geng ; Schetter, Aaron ; He, Peijun ; Funamizu, Naotake ; Gaedcke, Jochen ; Ghadimi, B Michael ; Ried, Thomas ; Hassan, Raffit ; Yfantis, Harris G ; Lee, Dong H ; Lacy, Curtis ; Maitra, Anirban ; Hanna, Nader ; Alexander, H Richard ; Hussain, S Perwez El-Rifai, WaelPloS one, 2012-02, Vol.7 (2), p.e31507 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
8 |
Material Type: Artigo
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Roles of EGFR, PI3K, AKT, and mTOR in Heavy Metal-Induced CancerCarpenter, Richard L ; Jiang, Bing-HuaCurrent cancer drug targets, 2013-03, Vol.13 (3), p.252-266 [Periódico revisado por pares]Netherlands: Bentham Science Publishers LtdTexto completo disponível |
9 |
Material Type: Artigo
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Promising New Agents for Colorectal CancerDas, Satya ; Ciombor, Kristen K. ; Haraldsdottir, Sigurdis ; Goldberg, Richard M.Current treatment options in oncology, 2018-06, Vol.19 (6), p.29-14, Article 29 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
10 |
Material Type: Artigo
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Chemotherapy resistance in osteosarcoma: current challenges and future directionsChou, Alexander J ; Gorlick, RichardExpert review of anticancer therapy, 2006-07, Vol.6 (7), p.1075-1085 [Periódico revisado por pares]England: Informa HealthcareTexto completo disponível |