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1
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
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Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

Hendel, Ayal ; Bak, Rasmus O ; Clark, Joseph T ; Kennedy, Andrew B ; Ryan, Daniel E ; Roy, Subhadeep ; Steinfeld, Israel ; Lunstad, Benjamin D ; Kaiser, Robert J ; Wilkens, Alec B ; Bacchetta, Rosa ; Tsalenko, Anya ; Dellinger, Douglas ; Bruhn, Laurakay ; Porteus, Matthew H

Nature biotechnology, 2015-09, Vol.33 (9), p.985-989 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
RNA modifications regulating cell fate in cancer
RNA modifications regulating cell fate in cancer
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RNA modifications regulating cell fate in cancer

Delaunay, Sylvain ; Frye, Michaela

Nature cell biology, 2019-05, Vol.21 (5), p.552-559 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Genetic and transcriptional evolution alters cancer cell line drug response
Genetic and transcriptional evolution alters cancer cell line drug response
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Genetic and transcriptional evolution alters cancer cell line drug response

Ben-David, Uri ; Siranosian, Benjamin ; Ha, Gavin ; Tang, Helen ; Oren, Yaara ; Hinohara, Kunihiko ; Strathdee, Craig A ; Dempster, Joshua ; Lyons, Nicholas J ; Burns, Robert ; Nag, Anwesha ; Kugener, Guillaume ; Cimini, Beth ; Tsvetkov, Peter ; Maruvka, Yosef E ; O'Rourke, Ryan ; Garrity, Anthony ; Tubelli, Andrew A ; Bandopadhayay, Pratiti ; Tsherniak, Aviad ; Vazquez, Francisca ; Wong, Bang ; Birger, Chet ; Ghandi, Mahmoud ; Thorner, Aaron R ; Bittker, Joshua A ; Meyerson, Matthew ; Getz, Gad ; Beroukhim, Rameen ; Golub, Todd R

Nature (London), 2018-08, Vol.560 (7718), p.325-330 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Highly efficient therapeutic gene editing of human hematopoietic stem cells
Highly efficient therapeutic gene editing of human hematopoietic stem cells
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Highly efficient therapeutic gene editing of human hematopoietic stem cells

Wu, Yuxuan ; Zeng, Jing ; Roscoe, Benjamin P ; Liu, Pengpeng ; Yao, Qiuming ; Lazzarotto, Cicera R ; Clement, Kendell ; Cole, Mitchel A ; Luk, Kevin ; Baricordi, Cristina ; Shen, Anne H ; Ren, Chunyan ; Esrick, Erica B ; Manis, John P ; Dorfman, David M ; Williams, David A ; Biffi, Alessandra ; Brugnara, Carlo ; Biasco, Luca ; Brendel, Christian ; Pinello, Luca ; Tsai, Shengdar Q ; Wolfe, Scot A ; Bauer, Daniel E

Nature medicine, 2019-05, Vol.25 (5), p.776-783 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Dev, Harveer ; Chiang, Ting-Wei Will ; Lescale, Chloe ; de Krijger, Inge ; Martin, Alistair G ; Pilger, Domenic ; Coates, Julia ; Sczaniecka-Clift, Matylda ; Wei, Wenming ; Ostermaier, Matthias ; Herzog, Mareike ; Lam, Jonathan ; Shea, Abigail ; Demir, Mukerrem ; Wu, Qian ; Yang, Fengtang ; Fu, Beiyuan ; Lai, Zhongwu ; Balmus, Gabriel ; Belotserkovskaya, Rimma ; Serra, Violeta ; O'Connor, Mark J ; Bruna, Alejandra ; Beli, Petra ; Pellegrini, Luca ; Caldas, Carlos ; Deriano, Ludovic ; Jacobs, Jacqueline J L ; Galanty, Yaron ; Jackson, Stephen P

Nature cell biology, 2018-08, Vol.20 (8), p.954-965 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
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Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

Eyquem, Justin ; Mansilla-Soto, Jorge ; Giavridis, Theodoros ; van der Stegen, Sjoukje J C ; Hamieh, Mohamad ; Cunanan, Kristen M ; Odak, Ashlesha ; Gönen, Mithat ; Sadelain, Michel

Nature (London), 2017-03, Vol.543 (7643), p.113-117 [Periódico revisado por pares]

England: Nature Publishing Group

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7
YAP1-induced MALAT1 promotes epithelial-mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer
YAP1-induced MALAT1 promotes epithelial-mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer
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YAP1-induced MALAT1 promotes epithelial-mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer

Sun, Zhenqiang ; Ou, Chunlin ; Liu, Jinbo ; Chen, Chen ; Zhou, Quanbo ; Yang, Shuaixi ; Li, Guiyuan ; Wang, Guixian ; Song, Junmin ; Li, Zhen ; Zhang, Zhiyong ; Yuan, Weitang ; Li, Xiayu

Oncogene, 2019-04, Vol.38 (14), p.2627-2644 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Chromatin architecture reorganization during stem cell differentiation
Chromatin architecture reorganization during stem cell differentiation
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Chromatin architecture reorganization during stem cell differentiation

Dixon, Jesse R ; Jung, Inkyung ; Selvaraj, Siddarth ; Shen, Yin ; Antosiewicz-Bourget, Jessica E ; Lee, Ah Young ; Ye, Zhen ; Kim, Audrey ; Rajagopal, Nisha ; Xie, Wei ; Diao, Yarui ; Liang, Jing ; Zhao, Huimin ; Lobanenkov, Victor V ; Ecker, Joseph R ; Thomson, James A ; Ren, Bing

Nature (London), 2015-02, Vol.518 (7539), p.331-336 [Periódico revisado por pares]

England: Nature Publishing Group

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9
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations
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Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations

Merkle, Florian T ; Ghosh, Sulagna ; Kamitaki, Nolan ; Mitchell, Jana ; Avior, Yishai ; Mello, Curtis ; Kashin, Seva ; Mekhoubad, Shila ; Ilic, Dusko ; Charlton, Maura ; Saphier, Genevieve ; Handsaker, Robert E ; Genovese, Giulio ; Bar, Shiran ; Benvenisty, Nissim ; McCarroll, Steven A ; Eggan, Kevin

Nature (London), 2017-05, Vol.545 (7653), p.229-233 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Biology and evolution of poorly differentiated neuroendocrine tumors
Biology and evolution of poorly differentiated neuroendocrine tumors
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Biology and evolution of poorly differentiated neuroendocrine tumors

Rickman, David S ; Beltran, Himisha ; Demichelis, Francesca ; Rubin, Mark A

Nature medicine, 2017-06, Vol.23 (6), p.1-673 [Periódico revisado por pares]

United States: Nature Publishing Group

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