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A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
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A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

Rosenfeld, Myrna R ; Ye, Xiaobu ; Supko, Jeffrey G ; Desideri, Serena ; Grossman, Stuart A ; Brem, Steven ; Mikkelson, Tom ; Wang, Daniel ; Chang, Yunyoung C ; Hu, Janice ; McAfee, Quentin ; Fisher, Joy ; Troxel, Andrea B ; Piao, Shengfu ; Heitjan, Daniel F ; Tan, Kay-See ; Pontiggia, Laura ; O'Dwyer, Peter J ; Davis, Lisa E ; Amaravadi, Ravi K

Autophagy, 2014-08, Vol.10 (8), p.1359-1368 [Periódico revisado por pares]

United States: Taylor & Francis

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2
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors
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Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors

Wainwright, Derek A ; Chang, Alan L ; Dey, Mahua ; Balyasnikova, Irina V ; Kim, Chung Kwon ; Tobias, Alex ; Cheng, Yu ; Kim, Julius W ; Qiao, Jian ; Zhang, Lingjiao ; Han, Yu ; Lesniak, Maciej S

Clinical cancer research, 2014-10, Vol.20 (20), p.5290-5301 [Periódico revisado por pares]

United States

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3
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
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Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

Shao, Huilin ; Chung, Jaehoon ; Lee, Kyungheon ; Balaj, Leonora ; Min, Changwook ; Carter, Bob S ; Hochberg, Fred H ; Breakefield, Xandra O ; Lee, Hakho ; Weissleder, Ralph

Nature communications, 2015-05, Vol.6 (1), p.6999-6999, Article 6999 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Rationale for poly(ADP-ribose) polymerase (PARP) inhibitors in combination therapy with camptothecins or temozolomide based on PARP trapping versus catalytic inhibition
Rationale for poly(ADP-ribose) polymerase (PARP) inhibitors in combination therapy with camptothecins or temozolomide based on PARP trapping versus catalytic inhibition
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Rationale for poly(ADP-ribose) polymerase (PARP) inhibitors in combination therapy with camptothecins or temozolomide based on PARP trapping versus catalytic inhibition

Murai, Junko ; Zhang, Yiping ; Morris, Joel ; Ji, Jiuping ; Takeda, Shunichi ; Doroshow, James H ; Pommier, Yves

The Journal of pharmacology and experimental therapeutics, 2014-06, Vol.349 (3), p.408-416 [Periódico revisado por pares]

United States: The American Society for Pharmacology and Experimental Therapeutics

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5
Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib
Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib
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Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib

Murai, Junko ; Huang, Shar-Yin N ; Renaud, Amèlie ; Zhang, Yiping ; Ji, Jiuping ; Takeda, Shunichi ; Morris, Joel ; Teicher, Beverly ; Doroshow, James H ; Pommier, Yves

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.433-443 [Periódico revisado por pares]

United States

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6
Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide
Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide
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Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide

Murphy, Susan F ; Varghese, Robin T ; Lamouille, Samy ; Guo, Sujuan ; Pridham, Kevin J ; Kanabur, Pratik ; Osimani, Alyssa M ; Sharma, Shaan ; Jourdan, Jane ; Rodgers, Cara M ; Simonds, Gary R ; Gourdie, Robert G ; Sheng, Zhi

Cancer research (Chicago, Ill.), 2016-01, Vol.76 (1), p.139-149 [Periódico revisado por pares]

United States

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7
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy
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Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy

Auffinger, B ; Tobias, A L ; Han, Y ; Lee, G ; Guo, D ; Dey, M ; Lesniak, M S ; Ahmed, A U

Cell death and differentiation, 2014-07, Vol.21 (7), p.1119-1131 [Periódico revisado por pares]

England: Nature Publishing Group

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8
OTX015 (MK‐8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models
OTX015 (MK‐8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models
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OTX015 (MK‐8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models

Berenguer‐Daizé, Caroline ; Astorgues‐Xerri, Lucile ; Odore, Elodie ; Cayol, Mylène ; Cvitkovic, Esteban ; Noel, Kay ; Bekradda, Mohamed ; MacKenzie, Sarah ; Rezai, Keyvan ; Lokiec, François ; Riveiro, Maria E. ; Ouafik, L'Houcine

International journal of cancer, 2016-11, Vol.139 (9), p.2047-2055 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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9
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
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Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance

Wickström, Malin ; Dyberg, Cecilia ; Milosevic, Jelena ; Einvik, Christer ; Calero, Raul ; Sveinbjörnsson, Baldur ; Sandén, Emma ; Darabi, Anna ; Siesjö, Peter ; Kool, Marcel ; Kogner, Per ; Baryawno, Ninib ; Johnsen, John Inge

Nature communications, 2015-11, Vol.6 (1), p.8904, Article 8904 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis
Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis
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Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis

Zhu, Zhongling ; Du, Shuangshuang ; Du, Yibo ; Ren, Jing ; Ying, Guoguang ; Yan, Zhao

Journal of neurochemistry, 2018-01, Vol.144 (1), p.93-104 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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