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KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
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KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Schumann, Gunter ; Liu, Chunyu ; O’Reilly, Paul ; Gao, He ; Song, Parkyong ; Xu, Bing ; Jia, Tianye ; Preis, Sarah ; Lepe, Marcelo Segura ; Akira, Shizuo ; Barbieri, Caterina ; Cauchi, Stephane ; Clarke, Toni-Kim ; Enroth, Stefan ; Fische, Kristar ; Harris, Sarah E. ; Hofer, Edith ; Hottenga, Jouke-Jan ; Joshi, Peter K. ; Kaartinen, Niina ; Lemaitre, Rozenn ; Luan, Jian’an ; Lyytikäinen, Leo-Pekka ; Manichaikul, Ani ; Mbarek, Hamdi ; Milaneschi, Yuri ; Moayyeri, Alireza ; Mukamal, Kenneth ; Nelson, Christopher ; Nettleton, Jennifer ; Partinen, Eemil ; Rawal, Rajesh ; Robino, Antonietta ; Rose, Lynda ; Sala, Cinzia ; Scott, Robert ; Smith, Albert Vernon ; Starr, John M. ; Teumer, Alexander ; Trompet, Stella ; Uitterlinden, André G. ; Venturini, Cristina ; Vergnaud, Anne-Claire ; Verweij, Niek ; Vitart, Veronique ; Vuckovic, Dragana ; Wedenoja, Juho ; Yengo, Loic ; Yu, Bing ; Zhang, Weihua ; Boomsma, Dorret I. ; Chambers, John ; Chasman, Daniel I. ; Daniela, Toniolo ; Deary, Ian ; Eriksson, Johan G. ; Esko, Tõnu ; Eulenburg, Volker ; Froguel, Philippe ; Gieger, Christian ; Grabe, Hans J. ; Gudnason, Vilmundur ; Harris, Tamara B. ; Hartikainen, Anna-Liisa ; Heath, Andrew C. ; Hocking, Lynne ; Hofman, Albert ; Jarvelin, Marjo-Riitta ; Jukema, J. Wouter ; Kaprio, Jaakko ; Kooner, Jaspal S. ; Kutalik, Zoltan ; Liu, Yongmei ; Madden, Pamela A. F. ; Morrison, Alanna ; Pirastu, Nicola ; Psaty, Bruce ; Raitakari, Olli ; Ridker, Paul ; Samani, Nilesh J. ; Schmidt, Helena ; Spector, Tim D. ; Strachan, David ; Tzoulaki, Ioanna ; van Duijn, Cornelia M. ; Marques-Vidal, Pedro ; Vollenweider, Peter ; Wareham, Nicholas J. ; Whitfield, John B. ; Wilson, James ; Wolffenbuttel, Bruce ; Bakalkin, Georgy ; Evangelou, Evangelos ; Liu, Yun ; Rice, Kenneth M. ; Desrivières, Sylvane ; Kliewer, Steven A. ; Mangelsdorf, David J. ; Müller, Christian P. ; Elliott, Paul

Proceedings of the National Academy of Sciences - PNAS, 2016-12, Vol.113 (50), p.14372-14377 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent
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Artigo
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Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent

Merchant, Mark ; Ma, Xiaolei ; Maun, Henry R ; Zheng, Zhong ; Peng, Jing ; Romero, Mally ; Huang, Arthur ; Yang, Nai-ying ; Nishimura, Merry ; Greve, Joan ; Santell, Lydia ; Zhang, Yu-Wen ; Su, Yanli ; Kaufman, Dafna W ; Billeci, Karen L ; Mai, Elaine ; Moffat, Barbara ; Lim, Amy ; Duenas, Eileen T ; Phillips, Heidi S ; Xiang, Hong ; Young, Judy C ; Vande Woude, George F ; Dennis, Mark S ; Reilly, Dorothea E ; Schwall, Ralph H ; Starovasnik, Melissa A ; Lazarus, Robert A ; Yansura, Daniel G

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (32), p.E2987-E2996 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Corrections: Unique insights into maternal mitochondrial inheritance in mice
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Corrections: Unique insights into maternal mitochondrial inheritance in mice

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (49), p.19969-19969 [Periódico revisado por pares]

NATIONAL ACADEMY OF SCIENCES

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4
COX2/mPGES1/PGE₂ pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells
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COX2/mPGES1/PGE₂ pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells

Prima, Victor ; Kaliberova, Lyudmila N. ; Kaliberov, Sergey ; Curiel, David T. ; Kusmartsev, Sergei

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (5), p.1117-1122 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Type 1 diabetes induction in humanized mice
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Type 1 diabetes induction in humanized mice

Tan, Shulian ; Li, Yang ; Xia, Jinxing ; Jin, Chun-Hui ; Hu, Zheng ; Duinkerken, Gaby ; Li, Yuying ; Maharlooei, Mohsen Khosravi ; Chavez, Estefania ; Nauman, Grace ; Danzl, Nichole ; Nakayama, Maki ; Roep, Bart O. ; Sykes, Megan ; Yang, Yong-Guang

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (41), p.10954-10959 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal–fetal interface
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Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal–fetal interface

Fu, Binqing ; Li, Xianchang ; Sun, Rui ; Tong, Xianhong ; Ling, Bin ; Tian, Zhigang ; Wei, Haiming

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (3), p.E231-E240 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
Mechanistic basis of infertility of mouse intersubspecific hybrids
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Mechanistic basis of infertility of mouse intersubspecific hybrids

Bhattacharyya, Tanmoy ; Gregorova, Sona ; Mihola, Ondrej ; Anger, Martin ; Sebestova, Jaroslava ; Denny, Paul ; Simecek, Petr ; Forejt, Jiri

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (6), p.E468-E477 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes
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Artigo
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Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Kowanetz, Marcin ; Wu, Xiumin ; Lee, John ; Tan, Martha ; Hagenbeek, Thijs ; Qu, Xueping ; Yu, Lanlan ; Ross, Jed ; Korsisaari, Nina ; Cao, Tim ; Bou-Reslan, Hani ; Kallop, Dara ; Weimer, Robby ; Ludlam, Mary J. C. ; Kaminker, Joshua S. ; Modrusan, Zora ; van Bruggen, Nicholas ; Peale, Franklin V. ; Carano, Richard ; Meng, Y. Gloria ; Ferrara, Napoleone

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21248-21255 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis
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Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis

Raverdeau, Mathilde ; Gely-Pernot, Aurore ; Féret, Betty ; Dennefeld, Christine ; Benoit, Gérard ; Davidson, Irwin ; Chambon, Pierre ; Mark, Manuel ; Ghyselinck, Norbert B

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.16582-16587 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
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Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells

Tekguc, Murat ; Wing, James Badger ; Osaki, Motonao ; Long, Jia ; Sakaguchi, Shimon

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (30) [Periódico revisado por pares]

United States: National Academy of Sciences

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