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Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program
Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program
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Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

Klarin, Derek ; Damrauer, Scott M ; Cho, Kelly ; Sun, Yan V ; Teslovich, Tanya M ; Honerlaw, Jacqueline ; Gagnon, David R ; DuVall, Scott L ; Li, Jin ; Peloso, Gina M ; Chaffin, Mark ; Small, Aeron M ; Huang, Jie ; Tang, Hua ; Lynch, Julie A ; Ho, Yuk-Lam ; Liu, Dajiang J ; Emdin, Connor A ; Li, Alexander H ; Huffman, Jennifer E ; Lee, Jennifer S ; Natarajan, Pradeep ; Chowdhury, Rajiv ; Saleheen, Danish ; Vujkovic, Marijana ; Baras, Aris ; Pyarajan, Saiju ; Di Angelantonio, Emanuele ; Neale, Benjamin M ; Naheed, Aliya ; Khera, Amit V ; Danesh, John ; Chang, Kyong-Mi ; Abecasis, Gonçalo ; Willer, Cristen ; Dewey, Frederick E ; Carey, David J ; Concato, John ; Gaziano, J Michael ; O'Donnell, Christopher J ; Tsao, Philip S ; Kathiresan, Sekar ; Rader, Daniel J ; Wilson, Peter W F ; Assimes, Themistocles L

Nature genetics, 2018-11, Vol.50 (11), p.1514-1523 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

Mercader, Josep M ; Udler, Miriam S ; Wessel, Jennifer ; Teslovich, Tanya M ; Caulkins, Lizz ; Barajas-Olmos, Francisco ; Boerwinkle, Eric ; Chen, Ling ; Contreras-Cubas, Cecilia ; Córdova, Emilio ; Correa, Adolfo ; DeFronzo, Ralph A ; Dolan, Lawrence ; Elliott, Amanda ; Floyd, James S ; Garay-Sevilla, Maria Eugenia ; García-Ortiz, Humberto ; Heard-Costa, Nancy L ; Jørgensen, Marit E ; Kang, Hyun Min ; Kelsey, Megan ; Linneberg, Allan ; Liu, Ching-Ti ; Liu, Jianjun ; Lyssenko, Valeriya ; Marcketta, Anthony ; Martínez-Hernández, Angélica ; Mayer-Davis, Elizabeth ; Morrison, Alanna C ; Ndungu, Anne ; Ng, Maggie C Y ; O'Dushlaine, Colm ; Post, Wendy S ; Vasan, Ramachandran S ; Rayner, N William ; Revilla-Monsalve, Cristina ; Santoro, Nicola ; Schurmann, Claudia ; Soberón, Xavier ; Strom, Tim M ; Thameem, Farook ; Torres, Jason M ; Vujkovic, Marijana ; Witte, Daniel R ; Atzmon, Gil ; Blangero, John ; Bonnycastle, Lori L ; Chan, Edmund ; Cheng, Ching-Yu ; Collins, Francis S ; de Vries, Paul S ; Glaser, Benjamin ; Gonzalez, Ma Elena ; Groop, Leif ; Kooner, Jaspal Singh ; Kwak, Soo Heon ; Laakso, Markku ; Nilsson, Peter ; Spector, Timothy D ; Tai, E Shyong ; Tuomilehto, Jaakko ; Wilson, James G ; Burke, Brian ; Carey, David J ; Frossard, Philippe ; Hwang, Mi Yeong ; Kim, Young Jin ; Kirchner, H Lester ; Lee, Jong-Young ; Lee, Juyoung ; Loos, Ruth J F ; Ma, Ronald C W ; Morris, Andrew D ; Palmer, Colin N A ; Pankow, James ; Rasheed, Asif ; Saleheen, Danish ; Sim, Xueling ; Small, Kerrin S ; Teo, Yik Ying ; Haiman, Christopher ; Hanis, Craig L ; Dewey, Frederick E ; Baras, Aris ; Gieger, Christian ; Meitinger, Thomas ; Lange, Leslie ; Pedersen, Oluf ; Zeitler, Philip ; Dabelea, Dana ; Abecasis, Goncalo ; Cox, Nancy J ; Sladek, Rob ; Meigs, James B ; Rotter, Jerome I ; Altshuler, David ; Burtt, Noël P ; Morris, Andrew P ; Florez, Jose C ; Boehnke, Michael

Nature (London), 2019-06, Vol.570 (7759), p.71-76 [Periódico revisado por pares]

England: Nature Publishing Group

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3
The genetic architecture of type 2 diabetes
The genetic architecture of type 2 diabetes
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The genetic architecture of type 2 diabetes

Teslovich, Tanya M ; Mahajan, Anubha ; Fontanillas, Pierre ; Moutsianas, Loukas ; Rivas, Manuel A ; Rayner, N William ; Cingolani, Pablo ; Lindgren, Cecilia M ; Chen, Yuhui ; Huang, Jinyan ; Varga, Tibor V ; Green, Todd ; Fingerlin, Tasha ; Horikoshi, Momoko ; Huh, Iksoo ; Lee, Juyoung ; Lee, Selyeong ; Maxwell, Taylor J ; Yoon, Joon ; Barzilai, Nir ; Han, Bok-Ghee ; Kuulasmaa, Teemu ; Balkau, Beverley ; Giedraitis, Vilmantas ; Purcell, Shaun ; Kwak, Soo-Heon ; Afzal, Uzma ; Aguilar, David ; Cheng, Ching-Yu ; Palli, Domenico ; Fowler, Sharon P ; Freedman, Barry I ; Hicks, Pamela J ; Musani, Solomon K ; Puppala, Sobha ; Wilson, Sr, Gregory ; Surdulescu, Gabriela L ; Herder, Christian ; Doney, Alex S F ; Kinnunen, Leena ; Hakaste, Liisa ; Jørgensen, Marit E ; Justesen, Johanne Marie ; Käräjämäki, Annemari ; Lannfelt, Lars ; Narisu, Narisu ; Melander, Olle ; Milani, Lili ; Neville, Matt ; Qi, Qibin ; Rolandsson, Olov ; Stirrups, Kathleen ; Blancher, Christine ; Maguire, Jared ; Shakir, Khalid ; DePristo, Mark ; de Angelis, Martin Hrabé ; Jun, Goo ; Murphy, Jacquelyn ; Onofrio, Robert ; Thorand, Barbara ; Meisinger, Christa ; Isomaa, Bo ; Rauramaa, Rainer ; Watanabe, Richard M ; Bergman, Richard N ; Bottinger, Erwin P ; Chan, Juliana C N ; Langenberg, Claudia ; Jablonski, Kathleen A ; Lehman, Donna M ; Froguel, Philippe ; Small, Kerrin S ; Grallert, Harald ; Glaser, Benjamin ; Banks, Eric ; Gieger, Christian ; Illig, Thomas ; Buck, Gemma ; Trakalo, Joseph ; Mägi, Reedik ; Farjoun, Yossi ; Owen, Katharine R ; Gloyn, Anna L ; Tuomi, Tiinamaija ; Kooner, Jaspal Singh ; Donnelly, Peter ; Morris, Andrew D ; Hattersley, Andrew T ; Bowden, Donald W ; Laakso, Markku ; Bell, Graeme I ; Duggirala, Ravindranath ; McVean, Gilean ; Meigs, James B ; Cox, Nancy J ; Mohlke, Karen L ; Florez, Jose C ; Morris, Andrew P ; Kang, Hyun Min

Nature (London), 2016-08, Vol.536 (7614), p.41-47 [Periódico revisado por pares]

England: Nature Publishing Group

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4
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
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An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Scott, Laura J ; Marullo, Letizia ; Gaulton, Kyle J ; Kaakinen, Marika ; Johnson, Andrew D ; Eicher, John D ; Lee, Yeji ; Ma, Clement ; Steinthorsdottir, Valgerdur ; Thorleifsson, Gudmar ; Van Zuydam, Natalie R ; Chen, Han ; Voight, Ben F ; Grallert, Harald ; Müller-Nurasyid, Martina ; Karssen, Lennart C ; van Leeuwen, Elisabeth M ; Willems, Sara M ; Fuchsberger, Christian ; Teslovich, Tanya M ; Chanda, Pritam ; Dina, Christian ; Yengo, Loic ; Jiang, Longda ; Sparso, Thomas ; Kestler, Hans A ; Eisele, Lewin ; Strawbridge, Rona J ; Benediktsson, Rafn ; Kong, Augustine ; Sigurðsson, Gunnar ; Kerrison, Nicola D ; Luan, Jian'an ; Roden, Michael ; Thorand, Barbara ; Fox, Caroline ; Liu, Ching-Ti ; Rybin, Denis ; Tuomi, Tiinamaija ; Couper, David J ; Jørgensen, Torben ; Linneberg, Allan ; Cornelis, Marilyn C ; Hunter, David J ; Kraft, Peter ; Sun, Qi ; Perry, John R B ; Wood, Andrew R ; Zeggini, Eleftheria ; Chines, Peter S ; Stringham, Heather M ; Mühleisen, Thomas W ; Nöthen, Markus M ; Pechlivanis, Sonali ; Humphries, Steve E ; Tremoli, Elena ; Klopp, Norman ; Mӓnnistö, Satu ; Charpentier, Guillaume ; Eury, Elodie ; Gigante, Bruna ; Leander, Karin ; Bottinger, Erwin P ; Blüher, Matthias ; Kovacs, Peter ; Scapoli, Chiara ; Erbel, Raimund ; Jöckel, Karl-Heinz ; Moebus, Susanne ; de Faire, Ulf ; Hamsten, Anders ; Stumvoll, Michael ; Donnelly, Peter J ; Frayling, Timothy M ; Hattersley, Andrew T ; Salomaa, Veikko ; Pedersen, Nancy L ; Mohlke, Karen L ; Barroso, Inês ; Lannfelt, Lars ; Ingelsson, Erik ; Lind, Lars ; Lindgren, Cecilia M ; Froguel, Philippe ; Palli, Domenico ; van der Schouw, Yvonne T ; Altshuler, David ; Groop, Leif C ; van Duijn, Cornelia M ; Florez, Jose C ; Meigs, James B ; Boerwinkle, Eric ; Strauch, Konstantin ; Metspalu, Andres ; Morris, Andrew D ; Hu, Frank B ; Thorsteinsdottir, Unnur ; Dupuis, Josée ; Morris, Andrew P ; Prokopenko, Inga

Diabetes (New York, N.Y.), 2017-11, Vol.66 (11), p.2888-2902 [Periódico revisado por pares]

United States: American Diabetes Association

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5
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Mahajan, Anubha ; Go, Min Jin ; Gaulton, Kyle J ; Prokopenko, Inga ; Wang, Xu ; Abecasis, Goncalo R ; Balkau, Beverley ; Barnett, Anthony H ; Beilby, John ; Bell, Graeme I ; Burtt, Noël ; Chang, Li-Ching ; Chen, Han ; Chidambaram, Manickam ; Chines, Peter S ; Cho, Nam H ; Cho, Young Min ; van Dam, Rob M ; Danesh, John ; Dedoussis, George ; Doney, Alex S ; Donnelly, Peter J ; Emilsson, Valur ; Eriksson, Johan G ; Florez, Jose C ; Forsen, Tom ; Fox, Caroline ; Fraser, Ross M ; Gigante, Bruna ; Grant, George B ; Grundberg, Elin ; Hamsten, Anders ; Hara, Kazuo ; Hattersley, Andrew T ; Herder, Christian ; Hveem, Kristian ; Hydrie, Zafar I ; Ingelsson, Erik ; Islam, Muhammed ; Jackson, Anne U ; Jafar, Tazeen ; Kadowaki, Takashi ; Kang, Hyun Min ; Kao, Wen Hong L ; Kato, Norihiro ; Kelly, Ann M ; Kim, Sangsoo ; Kong, Augustine ; Kraft, Peter ; Kravic, Jasmina ; Kumar, Ashish ; Kuusisto, Johanna ; Lagou, Vasiliki ; Langenberg, Claudia ; Lee, Jen-Mai ; Li, Yun ; Lindholm, Eero ; Loos, Ruth J F ; Maeda, Shiro ; Mägi, Reedik ; Männisto, Satu ; Matthews, David R ; Morris, Andrew D ; Navarro, Pau ; Pankow, James S ; Park, Kyong Soo ; Platou, Carl G ; Qi, Lu ; Rauramaa, Rainer ; Raychaudhuri, Soumya ; Rybin, Denis ; Saaristo, Timo E ; Saltevo, Juha ; Segrè, Ayellet V ; Sennblad, Bengt ; Sigurđsson, Gunnar ; Stefansson, Kari ; Steinthorsdottir, Valgerdur ; Stirrups, Kathleen ; Stringham, Heather M ; Suo, Chen ; Thorleifsson, Gudmar ; Tremoli, Elena ; Tsai, Fuu Jen ; Tuomilehto, Jaakko ; Veglia, Fabrizio ; Wareham, Nicholas J ; Wilsgaard, Tom ; Wilson, James F ; Wong, Tien Yin ; Wu, Ying ; Yamamoto, Ken ; Zhang, Fan ; Zheng, Wei ; Bowden, Donald W ; Cox, Nancy J ; Cruz, Miguel ; Seielstad, Mark ; Parra, Esteban J ; Morris, Andrew P

Nature genetics, 2014-03, Vol.46 (3), p.234-244 [Periódico revisado por pares]

United States: Nature Publishing Group

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6
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Zhao, Wei ; Robertson, Neil R ; Kitajima, Hidetoshi ; Taliun, Daniel ; Jensen, Richard A ; Lohman, Kurt K ; Flannick, Jason ; Grarup, Niels ; Trubetskoy, Vassily Vladimirovich ; Müller-Nurasyid, Martina ; Li-Gao, Ruifang ; Smith, Albert Vernon ; Ligthart, Symen ; Malerba, Giovanni ; Demirkan, Ayse ; Tajes, Juan Fernandez ; Preuss, Michael ; Graff, Marielisa ; Highland, Heather M ; Justice, Anne E ; Liu, Dajiang J ; Peloso, Gina Marie ; Afaq, Saima ; Afzal, Shoaib ; Almgren, Peter ; Amin, Najaf ; Bang, Lia B ; Brody, Jennifer A ; Canouil, Mickaël ; Chen, Yii-Der Ida ; Christensen, Cramer ; Eastwood, Sophie V ; Gambaro, Giovanni ; Grove, Megan L ; Hackinger, Sophie ; Tybjærg-Hansen, Anne ; Jäger, Susanne ; Jørgensen, Marit E ; Jørgensen, Torben ; Käräjämäki, Annemari ; Kovacs, Peter ; Kronenberg, Florian ; Lin, Keng-Hung ; Liu, Ching-Ti ; Loh, Marie ; Mamakou, Vasiliki ; McKean-Cowdin, Roberta ; Neville, Matt ; Nielsen, Sune F ; Ntalla, Ioanna ; Rice, Kenneth ; Rode, Line ; Rolandsson, Olov ; Selvin, Elizabeth ; Small, Kerrin S ; Surendran, Praveen ; Thorand, Barbara ; Thorleifsson, Gudmar ; Varbo, Anette ; Yengo, Loïc ; Young, Robin ; Boeing, Heiner ; Boerwinkle, Eric ; Dedoussis, George ; Dehghan, Abbas ; Florez, Jose C ; Frossard, Philippe ; Kuusisto, Johanna ; Launer, Lenore J ; Moitry, Marie ; Perola, Markus ; Rasheed, Asif ; Rosendaal, Frits R ; Rosengren, Anders H ; Sladek, Rob ; Smith, Blair H ; Varma, Rohit ; Willer, Cristen J ; Dupuis, Josée ; Franks, Paul W ; Groop, Leif ; Hansen, Torben ; Hattersley, Andrew T ; Ingelsson, Erik ; Karpe, Fredrik ; Kooner, Jaspal Singh ; Laakso, Markku ; Lind, Lars ; Liu, Yongmei ; Loos, Ruth J F ; Mook-Kanamori, Dennis ; Palmer, Colin N A ; Pankow, James S ; Rauramaa, Rainer ; Sattar, Naveed ; Soranzo, Nicole ; Stumvoll, Michael ; Barroso, Inês ; Saleheen, Danish ; Rotter, Jerome I

Nature genetics, 2018-04, Vol.50 (4), p.559-571 [Periódico revisado por pares]

United States: Nature Publishing Group

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7
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

MORRIS, Andrew P ; VOIGHT, Benjamin F ; PROKOPENKO, Inga ; HYUN MIN KANG ; DINA, Christian ; ESKOE, Tonu ; FRASER, Ross M ; KANONI, Stavroula ; KUMAR, Ashish ; LAGOU, Vasiliki ; LANGENBERG, Claudia ; LUAN, Jian'an ; TESLOVICH, Tanya M ; LINDGREN, Cecilia M ; MÜLLER-NURASYID, Martina ; PECHLIVANIS, Sonali ; RAYNER, N. William ; SCOTT, Laura J ; WILTSHIRE, Steven ; YENGO, Loic ; KINNUNEN, Leena ; ROSSIN, Elizabeth J ; RAYCHAUDHURI, Soumya ; FERREIRA, Teresa ; JOHNSON, Andrew D ; DIMAS, Antigones ; LOOS, Ruthj F ; VEDANTAM, Sailaja ; HAN CHEN ; FLOREZ, Jose C ; FOX, Caroline ; LIU, Ching-Ti ; RYBIN, Denis ; COUPER, David J ; SEGRE, Ayellet V ; KAO, Wen Hong L ; MAN LI ; CORNELIS, Marilyn C ; KRAFT, Peter ; QI SUN ; VAN DAM, Rob M ; STRINGHAM, Heather M ; CHINES, Peter S ; FISCHER, Krista ; FONTANILLAS, Pierre ; STEINTHORSDOTTIR, Valgerdur ; HOLMEN, Oddgeir L ; HUNT, Sarah E ; JACKSON, Anne U ; KONG, Augustine ; LAWRENCE, Robert ; MEYER, Julia ; PERRY, John R. B ; PLATOU, Carl G. P ; POTTER, Simon ; REHNBERG, Emil ; STRAWBRIDGE, Rona J ; KHAN, Hassan ; GRALLERT, Harald ; MAHAJAN, Anubha

Nature genetics, 2012-09, Vol.44 (9), p.981-990 [Periódico revisado por pares]

New York, NY: Nature Publishing Group

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8
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Mägi, Reedik ; Robertson, Neil ; Prokopenko, Inga ; Green, Todd ; Kestler, Hans ; Chheda, Himanshu ; Eisele, Lewin ; Steinthorsdottir, Valgerdur ; Kwan, Phoenix ; Lu, Yingchang ; van de Bunt, Martijn ; Chalisey, Anil ; Abecasis, Gonçalo R ; Charpentier, Guillaume ; Chines, Peter S ; Doney, Alex S F ; Edkins, Sarah ; Esko, Tonu ; Eury, Elodie ; Fontanillas, Pierre ; Franks, Paul W ; Gertow, Karl ; Gieger, Christian ; Hassinen, Maija ; Have, Christian T ; Herder, Christian ; Hreidarsson, Astradur B ; Hunter, David J ; Jørgensen, Marit E ; Jørgensen, Torben ; Kong, Augustine ; Kraft, Peter ; Kravic, Jasmina ; Liang, Liming ; Lindholm, Eero ; Liu, Ching-Ti ; Lobbens, Stéphane ; Luan, Jian'an ; Meyer, Julia ; Müller-Nurasyid, Martina ; Navarro, Carmen ; Oskolkov, Nikolay N ; Palli, Domenico ; Perry, John R B ; Platou, Carl G P ; Rybin, Denis ; van der Schouw, Yvonne T ; Stančáková, Alena ; Steinbach, Gerald ; Strauch, Konstantin ; Stringham, Heather M ; Thorand, Barbara ; Tonjes, Anke ; Wiltshire, Steven ; Zeggini, Eleftheria ; Dunham, Ian ; Pasquali, Lorenzo ; Loos, Ruth J F ; Boerwinkle, Eric ; Thorsteinsdottir, Unnur ; Stefansson, Kari ; Rauramaa, Rainer ; Stumvoll, Michael ; Pedersen, Nancy L ; Keinanen-Kiukaanniemi, Sirkka M ; Korpi-Hyövälti, Eeva ; Kuusisto, Johanna ; Laakso, Markku ; Jöcke, Karl-Heinz ; Ripatti, Samuli ; Boehm, Bernhard O ; Bergman, Richard N ; Collins, Francis S ; Mohlke, Karen L ; Koistinen, Heikki ; Tuomilehto, Jaakko ; Hveem, Kristian ; Njølstad, Inger ; Deloukas, Panagiotis ; Frayling, Timothy M ; Hattersley, Andrew T ; de Faire, Ulf ; Hamsten, Anders ; Illig, Thomas ; Cauchi, Stephane ; Sladek, Rob ; Froguel, Philippe ; Hansen, Torben ; Pedersen, Oluf ; Morris, Andrew D ; Palmer, Collin N A ; Kathiresan, Sekar ; Melander, Olle ; Langenberg, Claudia ; Wareham, Nicholas J ; O'Callaghan, Christopher A ; Gloyn, Anna L ; Altshuler, David ; McCarthy, Mark I ; Morris, Andrew P

Nature genetics, 2015-12, Vol.47 (12), p.1415-1425 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
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Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico

Williams, Amy L ; Jacobs, Suzanne B R ; Moreno-Macías, Hortensia ; Huerta-Chagoya, Alicia ; Churchhouse, Claire ; Márquez-Luna, Carla ; García-Ortíz, Humberto ; Gómez-Vázquez, María José ; Burtt, Noël P ; Aguilar-Salinas, Carlos A ; González-Villalpando, Clicerio ; Florez, Jose C ; Orozco, Lorena ; Haiman, Christopher A ; Tusié-Luna, Teresa ; Altshuler, David

Nature (London), 2014-02, Vol.506 (7486), p.97-101 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
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Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes

Majithia, Amit R. ; Flannick, Jason ; Shahinian, Peter ; Guo, Michael ; Bray, Mark-Anthony ; Fontanillas, Pierre ; Gabriel, Stacey B. ; Rosen, Evan D. ; Altshuler, David

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (36), p.13127-13132 [Periódico revisado por pares]

United States: National Academy of Sciences

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