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Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling
Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling
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Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling

Bender, Andrew T ; Gardberg, Anna ; Pereira, Albertina ; Johnson, Theresa ; Wu, Yin ; Grenningloh, Roland ; Head, Jared ; Morandi, Federica ; Haselmayer, Philipp ; Liu-Bujalski, Lesley

Molecular pharmacology, 2017-03, Vol.91 (3), p.208-219 [Periódico revisado por pares]

United States

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2
Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models
Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models
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Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models

Haselmayer, Philipp ; Camps, Montserrat ; Liu-Bujalski, Lesley ; Nguyen, Ngan ; Morandi, Federica ; Head, Jared ; O'Mahony, Alison ; Zimmerli, Simone C ; Bruns, Lisa ; Bender, Andrew T ; Schroeder, Patricia ; Grenningloh, Roland

The Journal of immunology (1950), 2019-05, Vol.202 (10), p.2888-2906 [Periódico revisado por pares]

United States: AAI

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3
The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo
The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo
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The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo

Martin, Lesley-Ann ; Head, Julia E ; Pancholi, Sunil ; Salter, Janine ; Quinn, Emma ; Detre, Simone ; Kaye, Stan ; Howes, Angela ; Dowsett, Mitch ; Johnston, Stephen R D

Molecular cancer therapeutics, 2007-09, Vol.6 (9), p.2458-2467 [Periódico revisado por pares]

United States: American Association for Cancer Research

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4
Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer
Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer
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Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer

Johnston, Stephen R D ; Head, Julia ; Pancholi, Sunil ; Detre, Simone ; Martin, Lesley-Ann ; Smith, Ian E ; Dowsett, Mitch

Clinical cancer research, 2003-01, Vol.9 (1 Pt 2), p.524S-32S [Periódico revisado por pares]

United States

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