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1 |
Material Type: Artigo
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Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided designOgden, Pierce J ; Kelsic, Eric D ; Sinai, Sam ; Church, George MScience (American Association for the Advancement of Science), 2019-11, Vol.366 (6469), p.1139-1143 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Deep diversification of an AAV capsid protein by machine learningBryant, Drew H ; Bashir, Ali ; Sinai, Sam ; Jain, Nina K ; Ogden, Pierce J ; Riley, Patrick F ; Church, George M ; Colwell, Lucy J ; Kelsic, Eric DNature biotechnology, 2021-06, Vol.39 (6), p.691-696 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Characterization of two classes of small molecule inhibitors of Arp2/3 complexPollard, T. D ; Nolen, B. J ; Tomasevic, N ; Russell, A ; Pierce, D. W ; Jia, Z ; McCormick, C. D ; Hartman, J ; Sakowicz, RNature (London), 2009-08, Vol.460 (7258), p.1031-1034 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Transfer of ubiquitin protein caught in the actDeshaies, Raymond J ; Pierce, Nathan WNature (London), 2020-02, Vol.578 (7795), p.372-373 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoniMarek, Martin ; Kannan, Srinivasaraghavan ; Hauser, Alexander-Thomas ; Moraes Mourão, Marina ; Caby, Stéphanie ; Cura, Vincent ; Stolfa, Diana A ; Schmidtkunz, Karin ; Lancelot, Julien ; Andrade, Luiza ; Renaud, Jean-Paul ; Oliveira, Guilherme ; Sippl, Wolfgang ; Jung, Manfred ; Cavarelli, Jean ; Pierce, Raymond J ; Romier, Christophe Geary, Timothy G.PLoS pathogens, 2013-09, Vol.9 (9), p.e1003645-e1003645 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Comprehensive mutagenesis maps the effect of all single-codon mutations in the AAV2 rep gene on AAV productionJain, Nina K ; Ogden, Pierce J ; Church, George MeLife, 2024-03, Vol.12 [Periódico revisado por pares]England: eLife Sciences Publications LtdTexto completo disponível |
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Material Type: Artigo
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Transcriptional analysis of South African cassava mosaic virus-infected susceptible and tolerant landraces of cassava highlights differences in resistance, basal defense and cell wall associated genes during infectionAllie, Farhahna ; Pierce, Erica J ; Okoniewski, Michal J ; Rey, ChrissieBMC genomics, 2014-11, Vol.15 (1), p.1006-1006, Article 1006 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
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Material Type: Artigo
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TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombinationChandler, Benjamin C ; Moubadder, Leah ; Ritter, Cassandra L ; Liu, Meilan ; Cameron, Meleah ; Wilder-Romans, Kari ; Zhang, Amanda ; Pesch, Andrea M ; Michmerhuizen, Anna R ; Hirsh, Nicole ; Androsiglio, Marlie ; Ward, Tanner ; Olsen, Eric ; Niknafs, Yashar S ; Merajver, Sofia ; Thomas, Dafydd G ; Brown, Powel H ; Lawrence, Theodore S ; Nyati, Shyam ; Pierce, Lori J ; Chinnaiyan, Arul ; Speers, CoreyThe Journal of clinical investigation, 2020-02, Vol.130 (2), p.958-973 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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Material Type: Artigo
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Histone Deacetylase (HDAC) Inhibitors for the Treatment of SchistosomiasisGhazy, Ehab ; Abdelsalam, Mohamed ; Robaa, Dina ; Pierce, Raymond J ; Sippl, WolfgangPharmaceuticals (Basel, Switzerland), 2022-01, Vol.15 (1), p.80 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Material Type: Artigo
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Translocation machinery for synthesis of integral membrane and secretory proteins in dendritic spinesMcCarthy, J. B ; Pierce, J. P ; van Leyen, KNature neuroscience, 2000-04, Vol.3 (4), p.311-313 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |