Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
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1 |
Material Type: Livro
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Mutagenesis of the Mouse GenomeMonica J. Justice Mary Ann Bedell; Monica Justice; Mary BedellSpringer Netherlands 2004Acesso online. A biblioteca também possui exemplares impressos. |
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2 |
Material Type: Artigo
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Tissue-specific mutation accumulation in human adult stem cells during lifeBlokzijl, Francis ; de Ligt, Joep ; Jager, Myrthe ; Sasselli, Valentina ; Roerink, Sophie ; Sasaki, Nobuo ; Huch, Meritxell ; Boymans, Sander ; Kuijk, Ewart ; Prins, Pjotr ; Nijman, Isaac J ; Martincorena, Inigo ; Mokry, Michal ; Wiegerinck, Caroline L ; Middendorp, Sabine ; Sato, Toshiro ; Schwank, Gerald ; Nieuwenhuis, Edward E S ; Verstegen, Monique M A ; van der Laan, Luc J W ; de Jonge, Jeroen ; IJzermans, Jan N M ; Vries, Robert G ; van de Wetering, Marc ; Stratton, Michael R ; Clevers, Hans ; Cuppen, Edwin ; van Boxtel, RubenNature (London), 2016-10, Vol.538 (7624), p.260-264 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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3 |
Material Type: Artigo
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Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophyRyu, Seuk-Min ; Koo, Taeyoung ; Kim, Kyoungmi ; Lim, Kayeong ; Baek, Gayoung ; Kim, Sang-Tae ; Kim, Heon Seok ; Kim, Da-Eun ; Lee, Hyunji ; Chung, Eugene ; Kim, Jin-SooNature biotechnology, 2018-07, Vol.36 (6), p.536-539 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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4 |
Material Type: Artigo
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ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in miceMathur, Radhika ; Alver, Burak H ; San Roman, Adrianna K ; Wilson, Boris G ; Wang, Xiaofeng ; Agoston, Agoston T ; Park, Peter J ; Shivdasani, Ramesh A ; Roberts, Charles W MNature genetics, 2017-02, Vol.49 (2), p.296-302 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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5 |
Material Type: Artigo
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Neurodevelopmental disease genes implicated by de novo mutation and copy number variation morbidityCoe, Bradley P ; Stessman, Holly A F ; Sulovari, Arvis ; Geisheker, Madeleine R ; Bakken, Trygve E ; Lake, Allison M ; Dougherty, Joseph D ; Lein, Ed S ; Hormozdiari, Fereydoun ; Bernier, Raphael A ; Eichler, Evan ENature genetics, 2019-01, Vol.51 (1), p.106-116 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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6 |
Material Type: Artigo
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A Mouse Model of Mitochondrial Disease Reveals Germline Selection against Severe mtDNA MutationsFan, Weiwei ; Waymire, Katrina G. ; Narula, Navneet ; Li, Peng ; Rocher, Christophe ; Coskun, Pinar E. ; Vannan, Mani A. ; Narula, Jagat ; MacGregor, Grant R. ; Wallace, Douglas C.Science (American Association for the Advancement of Science), 2008-02, Vol.319 (5865), p.958-962 [Periódico revisado por pares]Washington, DC: American Association for the Advancement of ScienceTexto completo disponível |
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7 |
Material Type: Artigo
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A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignanciesBoettcher, Steffen ; Miller, Peter G ; Sharma, Rohan ; McConkey, Marie ; Leventhal, Matthew ; Krivtsov, Andrei V ; Giacomelli, Andrew O ; Wong, Waihay ; Kim, Jesi ; Chao, Sherry ; Kurppa, Kari J ; Yang, Xiaoping ; Milenkowic, Kirsten ; Piccioni, Federica ; Root, David E ; Rücker, Frank G ; Flamand, Yael ; Neuberg, Donna ; Lindsley, R Coleman ; Jänne, Pasi A ; Hahn, William C ; Jacks, Tyler ; Döhner, Hartmut ; Armstrong, Scott A ; Ebert, Benjamin LScience (American Association for the Advancement of Science), 2019-08, Vol.365 (6453), p.599-604 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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8 |
Material Type: Artigo
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Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndromeSantiago-Fernández, Olaya ; Osorio, Fernando G ; Quesada, Víctor ; Rodríguez, Francisco ; Basso, Sammy ; Maeso, Daniel ; Rolas, Loïc ; Barkaway, Anna ; Nourshargh, Sussan ; Folgueras, Alicia R ; Freije, José M P ; López-Otín, CarlosNature medicine, 2019-03, Vol.25 (3), p.423-426 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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9 |
Material Type: Artigo
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Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancersHodges, H Courtney ; Stanton, Benjamin Z ; Cermakova, Katerina ; Chang, Chiung-Ying ; Miller, Erik L ; Kirkland, Jacob G ; Ku, Wai Lim ; Veverka, Vaclav ; Zhao, Keji ; Crabtree, Gerald RNature structural & molecular biology, 2018-01, Vol.25 (1), p.61-72 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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10 |
Material Type: Artigo
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A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronismFernandes-Rosa, Fabio L ; Daniil, Georgios ; Orozco, Ian J ; Göppner, Corinna ; El Zein, Rami ; Jain, Vandana ; Boulkroun, Sheerazed ; Jeunemaitre, Xavier ; Amar, Laurence ; Lefebvre, Hervé ; Schwarzmayr, Thomas ; Strom, Tim M ; Jentsch, Thomas J ; Zennaro, Maria-ChristinaNature genetics, 2018-03, Vol.50 (3), p.355-361 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |