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Beyond the One Gene–One Disease Paradigm: Complex Genetics and Pleiotropy in Inheritable Cardiac DisordersCerrone, Marina ; Remme, Carol Ann ; Tadros, Rafik ; Bezzina, Connie R ; Delmar, MarioCirculation (New York, N.Y.), 2019-08, Vol.140 (7), p.595-610 [Periódico revisado por pares]United States: by the American College of Cardiology Foundation and the American Heart Association, IncTexto completo disponível |
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The many faces of pleiotropyPaaby, Annalise B ; Rockman, Matthew VTrends in genetics, 2013-02, Vol.29 (2), p.66-73 [Periódico revisado por pares]Amsterdam: Elsevier LtdTexto completo disponível |
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Antagonistic Pleiotropy in Human DiseaseByars, Sean G. ; Voskarides, KonstantinosJournal of molecular evolution, 2020, Vol.88 (1), p.12-25 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Evolutionary dynamics of bacteria in a human host environmentYang, Lei ; Jelsbak, Lars ; Marvig, Rasmus Lykke ; Damkiær, Søren ; Workman, Christopher T ; Rau, Martin Holm ; Hansen, Susse Kirkelund ; Folkesson, Anders ; Johansen, Helle Krogh ; Ciofu, Oana ; Høiby, Niels ; Sommer, Morten O.A ; Molin, SørenProceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (18), p.7481-7486 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian HemoglobinKumar, Amit ; Natarajan, Chandrasekhar ; Moriyama, Hideaki ; Witt, Christopher C ; Weber, Roy E ; Fago, Angela ; Storz, Jay FMolecular biology and evolution, 2017-05, Vol.34 (5), p.1240-1251 [Periódico revisado por pares]United States: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Pleiotropy facilitates local adaptation to distant optima in common ragweed (Ambrosia artemisiifolia)Hämälä, Tuomas ; Gorton, Amanda J ; Moeller, David A ; Tiffin, Peter de Meaux, JuliettePLoS genetics, 2020-03, Vol.16 (3), p.e1008707-e1008707 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Pleiotropic effects of the wheat domestication gene Q on yield and grain morphologyXie, Quan ; Li, Na ; Yang, Yang ; Lv, Yulong ; Yao, Hongni ; Wei, Rong ; Sparkes, Debbie L. ; Ma, ZhengqiangPlanta, 2018-05, Vol.247 (5), p.1089-1098 [Periódico revisado por pares]Berlin/Heidelberg: Springer Science + Business MediaTexto completo disponível |
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Material Type: Artigo
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Environment-dependent pleiotropic effects of mutations on the maximum growth rate r and carrying capacity K of population growthWei, Xinzhu ; Zhang, Jianzhi Pál, CsabaPLoS biology, 2019-01, Vol.17 (1), p.e3000121-e3000121 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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A SNP Mutation of SiCRC Regulates Seed Number Per Capsule and Capsule Length of cs1 Mutant in SesameWei, Libin ; Li, Chun ; Duan, Yinghui ; Qu, Wenwen ; Wang, Huili ; Miao, Hongmei ; Zhang, HaiyangInternational journal of molecular sciences, 2019-08, Vol.20 (16), p.4056 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Material Type: Artigo
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Unraveling the complex genetic model for cystic fibrosis: pleiotropic effects of modifier genes on early cystic fibrosis-related morbiditiesLi, Weili ; Soave, David ; Miller, Melissa R. ; Keenan, Katherine ; Lin, Fan ; Gong, Jiafen ; Chiang, Theodore ; Stephenson, Anne L. ; Durie, Peter ; Rommens, Johanna ; Sun, Lei ; Strug, Lisa J.Human genetics, 2014-02, Vol.133 (2), p.151-161 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |