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1
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
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Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

Jain, Mohit ; Nilsson, Roland ; Sharma, Sonia ; Madhusudhan, Nikhil ; Kitami, Toshimori ; Souza, Amanda L. ; Kafri, Ran ; Kirschner, Marc W. ; Clish, Clary B. ; Mootha, Vamsi K.

Science (American Association for the Advancement of Science), 2012-05, Vol.336 (6084), p.1040-1044 [Periódico revisado por pares]

Washington, DC: American Association for the Advancement of Science

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2
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
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Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

Iliopoulos, Dimitrios ; Hirsch, Heather A. ; Wang, Guannan ; Struhl, Kevin

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (4), p.1397-1402 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand
GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand
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GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand

Yang, Linda ; Chang, Chih-Chuan ; Sun, Zhe ; Madsen, Dennis ; Zhu, Haisun ; Padkjær, Søren B ; Wu, Xiaoai ; Huang, Tao ; Hultman, Karin ; Paulsen, Sarah J ; Wang, Jishu ; Bugge, Anne ; Frantzen, Jane Boesen ; Nørgaard, Per ; Jeppesen, Jacob Fuglsbjerg ; Yang, Zhiru ; Secher, Anna ; Chen, Haibin ; Li, Xun ; John, Linu Mary ; Shan, Bing ; He, Zhenhua ; Gao, Xiang ; Su, Jing ; Hansen, Kristian T ; Yang, Wei ; Jørgensen, Sebastian Beck

Nature medicine, 2017-10, Vol.23 (10), p.1158-1166 [Periódico revisado por pares]

United States: Nature Publishing Group

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4
Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells
Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells
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Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

Suzuki, Jun ; Denning, Daniel P. ; Imanishi, Eiichi ; Horvitz, H. Robert ; Nagata, Shigekazu

Science (American Association for the Advancement of Science), 2013-07, Vol.341 (6144), p.403-406 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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5
Senescence-associated reprogramming promotes cancer stemness
Senescence-associated reprogramming promotes cancer stemness
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Senescence-associated reprogramming promotes cancer stemness

Milanovic, Maja ; Fan, Dorothy N Y ; Belenki, Dimitri ; Däbritz, J Henry M ; Zhao, Zhen ; Yu, Yong ; Dörr, Jan R ; Dimitrova, Lora ; Lenze, Dido ; Monteiro Barbosa, Ines A ; Mendoza-Parra, Marco A ; Kanashova, Tamara ; Metzner, Marlen ; Pardon, Katharina ; Reimann, Maurice ; Trumpp, Andreas ; Dörken, Bernd ; Zuber, Johannes ; Gronemeyer, Hinrich ; Hummel, Michael ; Dittmar, Gunnar ; Lee, Soyoung ; Schmitt, Clemens A

Nature (London), 2018-01, Vol.553 (7686), p.96-100 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation
Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation
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Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation

Gough, Daniel J ; Corlett, Alicia ; Schlessinger, Karni ; Wegrzyn, Joanna ; Larner, Andrew C ; Levy, David E

Science (American Association for the Advancement of Science), 2009-06, Vol.324 (5935), p.1713-1716 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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7
GDF15 mediates the effects of metformin on body weight and energy balance
GDF15 mediates the effects of metformin on body weight and energy balance
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GDF15 mediates the effects of metformin on body weight and energy balance

Coll, Anthony P ; Chen, Michael ; Taskar, Pranali ; Rimmington, Debra ; Patel, Satish ; Tadross, John A ; Cimino, Irene ; Yang, Ming ; Welsh, Paul ; Virtue, Samuel ; Goldspink, Deborah A ; Miedzybrodzka, Emily L ; Konopka, Adam R ; Esponda, Raul Ruiz ; Huang, Jeffrey T-J ; Tung, Y C Loraine ; Rodriguez-Cuenca, Sergio ; Tomaz, Rute A ; Harding, Heather P ; Melvin, Audrey ; Yeo, Giles S H ; Preiss, David ; Vidal-Puig, Antonio ; Vallier, Ludovic ; Nair, K Sreekumaran ; Wareham, Nicholas J ; Ron, David ; Gribble, Fiona M ; Reimann, Frank ; Sattar, Naveed ; Savage, David B ; Allan, Bernard B ; O'Rahilly, Stephen

Nature (London), 2020-02, Vol.578 (7795), p.444-448 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
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Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

Kinker, Gabriela S ; Greenwald, Alissa C ; Tal, Rotem ; Orlova, Zhanna ; Cuoco, Michael S ; McFarland, James M ; Warren, Allison ; Rodman, Christopher ; Roth, Jennifer A ; Bender, Samantha A ; Kumar, Bhavna ; Rocco, James W ; Fernandes, Pedro A C M ; Mader, Christopher C ; Keren-Shaul, Hadas ; Plotnikov, Alexander ; Barr, Haim ; Tsherniak, Aviad ; Rozenblatt-Rosen, Orit ; Krizhanovsky, Valery ; Puram, Sidharth V ; Regev, Aviv ; Tirosh, Itay

Nature genetics, 2020-11, Vol.52 (11), p.1208-1218 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
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Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

Janzer, Andreas ; German, Natalie J. ; Gonzalez-Herrera, Karina N. ; Asara, John M. ; Haigis, Marcia C. ; Struhl, Kevin

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10574-10579 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice
Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice
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Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice

Suriben, Rowena ; Chen, Michael ; Higbee, Jared ; Oeffinger, Julie ; Ventura, Richard ; Li, Betty ; Mondal, Kalyani ; Gao, Zhengyu ; Ayupova, Dina ; Taskar, Pranali ; Li, Diana ; Starck, Shelley R ; Chen, Hung-I Harry ; McEntee, Michele ; Katewa, Subhash D ; Phung, Van ; Wang, Marilyn ; Kekatpure, Avantika ; Lakshminarasimhan, Damodharan ; White, Andre ; Olland, Andrea ; Haldankar, Raj ; Solloway, Mark J ; Hsu, Jer-Yuan ; Wang, Yan ; Tang, Jie ; Lindhout, Darrin A ; Allan, Bernard B

Nature medicine, 2020-08, Vol.26 (8), p.1264-1270 [Periódico revisado por pares]

United States: Nature Publishing Group

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