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1
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
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Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

Iliopoulos, Dimitrios ; Hirsch, Heather A. ; Wang, Guannan ; Struhl, Kevin

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (4), p.1397-1402 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
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Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

Janzer, Andreas ; German, Natalie J. ; Gonzalez-Herrera, Karina N. ; Asara, John M. ; Haigis, Marcia C. ; Struhl, Kevin

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10574-10579 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

Cheung, Hiu Wing ; Cowley, Glenn S ; Weir, Barbara A ; Boehm, Jesse S ; Rusin, Scott ; Scott, Justine A ; East, Alexandra ; Ali, Levi D ; Lizotte, Patrick H ; Wong, Terence C ; Jiang, Guozhi ; Hsiao, Jessica ; Mermel, Craig H ; Getz, Gad ; Barretina, Jordi ; Gopal, Shuba ; Tamayo, Pablo ; Gould, Joshua ; Tsherniak, Aviad ; Stransky, Nicolas ; Luo, Biao ; Ren, Yin ; Drapkin, Ronny ; Bhatia, Sangeeta N ; Mesirov, Jill P ; Garraway, Levi A ; Meyerson, Matthew ; Lander, Eric S ; Root, David E ; Hahn, William C

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (30), p.12372-12377 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas
Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas
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Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas

Sievert, Angela J. ; Lang, Shih-Shan ; Boucher, Katie L. ; Madsen, Peter J. ; Slaunwhite, Erin ; Choudhari, Namrata ; Kellet, Meghan ; Storm, Phillip B. ; Resnick, Adam C.

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.5957-5962 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Identifying Genes Important for Spermatogonial Stem Cell Self-Renewal and Survival
Identifying Genes Important for Spermatogonial Stem Cell Self-Renewal and Survival
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Identifying Genes Important for Spermatogonial Stem Cell Self-Renewal and Survival

Oatley, Jon M. ; Avarbock, Mary R. ; Telaranta, Aino I. ; Fearon, Douglas T. ; Brinster, Ralph L.

Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (25), p.9524-9529 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Microfluidics separation reveals the stem-cell–like deformability of tumor-initiating cells
Microfluidics separation reveals the stem-cell–like deformability of tumor-initiating cells
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Microfluidics separation reveals the stem-cell–like deformability of tumor-initiating cells

Zhang, Weijia ; Kai, Kazuharu ; Choi, Dong Soon ; Iwamoto, Takayuki ; Nguyen, Yen H ; Wong, Helen ; Landis, Melissa D ; Ueno, Naoto T ; Chang, Jenny ; Qin, Lidong

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (46), p.18707-18712 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
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Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair

Yu, Helen ; Pak, Helen ; Hammond-Martel, Ian ; Ghram, Mehdi ; Rodrigue, Amélie ; Daou, Salima ; Barbour, Haithem ; Corbeil, Luc ; Hébert, Josée ; Drobetsky, Elliot ; Masson, Jean Yves ; Noia, Javier M. Di ; El Bachir Affar

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (1), p.285-290 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
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Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

Hirsch, Heather A. ; Iliopoulos, Dimitrios ; Struhl, Kevin

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (3), p.972-977 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Characterizing deformability and surface friction of cancer cells
Characterizing deformability and surface friction of cancer cells
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Characterizing deformability and surface friction of cancer cells

Byun, Sangwon ; Son, Sungmin ; Amodei, Dario ; Cermak, Nathan ; Shaw, Josephine ; Kang, Joon Ho ; Hecht, Vivian C. ; Winslow, Monte M. ; Jacks, Tyler ; Mallick, Parag ; Manalis, Scott R.

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (19), p.7580-7585 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells
Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells
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Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells

Janssen, Aniek ; Kops, Geert J.P.L ; Medema, René H

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (45), p.19108-19113 [Periódico revisado por pares]

United States: National Academy of Sciences

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