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An Aggregation Advisor for Ligand Discovery
An Aggregation Advisor for Ligand Discovery
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An Aggregation Advisor for Ligand Discovery

Irwin, John J. ; Duan, Da ; Torosyan, Hayarpi ; Doak, Allison K. ; Ziebart, Kristin T. ; Sterling, Teague ; Tumanian, Gurgen ; Shoichet, Brian K.

Journal of medicinal chemistry, 2015-09, Vol.58 (17), p.7076-7087 [Periódico revisado por pares]

United States: American Chemical Society

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2
Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability
Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability
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Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability

Schönauer, Ria ; Els-Heindl, Sylvia ; Fischer, Jan-Patrick ; Köbberling, Johannes ; Riedl, Bernd ; Beck-Sickinger, Annette G

Journal of medicinal chemistry, 2016-06, Vol.59 (12), p.5695-5705 [Periódico revisado por pares]

United States: American Chemical Society

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3
Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds
Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds
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Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds

Drapier, Thomas ; Geubelle, Pierre ; Bouckaert, Charlotte ; Nielsen, Lise ; Laulumaa, Saara ; Goffin, Eric ; Dilly, Sébastien ; Francotte, Pierre ; Hanson, Julien ; Pochet, Lionel ; Kastrup, Jette Sandholm ; Pirotte, Bernard

Journal of medicinal chemistry, 2018-06, Vol.61 (12), p.5279-5291 [Periódico revisado por pares]

United States: American Chemical Society

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4
7‑Phenoxy-Substituted 3,4-Dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α‑Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency
7‑Phenoxy-Substituted 3,4-Dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α‑Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency
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7‑Phenoxy-Substituted 3,4-Dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α‑Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency

Goffin, Eric ; Drapier, Thomas ; Larsen, Anja Probst ; Geubelle, Pierre ; Ptak, Christopher P ; Laulumaa, Saara ; Rovinskaja, Karoline ; Gilissen, Julie ; Tullio, Pascal de ; Olsen, Lars ; Frydenvang, Karla ; Pirotte, Bernard ; Hanson, Julien ; Oswald, Robert E ; Kastrup, Jette Sandholm ; Francotte, Pierre

Journal of medicinal chemistry, 2018-01, Vol.61 (1), p.251-264 [Periódico revisado por pares]

United States: American Chemical Society

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5
Beware the Receptor Variants
Beware the Receptor Variants
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Beware the Receptor Variants

Hanson, Julien

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.15671-15673 [Periódico revisado por pares]

United States: American Chemical Society

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6
Metabolomics as a Challenging Approach for Medicinal Chemistry and Personalized Medicine
Metabolomics as a Challenging Approach for Medicinal Chemistry and Personalized Medicine
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Metabolomics as a Challenging Approach for Medicinal Chemistry and Personalized Medicine

Frédérich, Michel ; Pirotte, Bernard ; Fillet, Marianne ; de Tullio, Pascal

Journal of medicinal chemistry, 2016-10, Vol.59 (19), p.8649-8666 [Periódico revisado por pares]

United States: American Chemical Society

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7
Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency
Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency
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Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency

Pillaiyar, Thanigaimalai ; Wozniak, Monika ; Abboud, Dayana ; Rasch, Alexander ; Liebing, Aenne-Dorothea ; Poso, Antti ; Kronenberger, Thales ; Stäubert, Claudia ; Laufer, Stefan A. ; Hanson, Julien

Journal of medicinal chemistry, 2023-12, Vol.66 (24), p.17118-17137 [Periódico revisado por pares]

United States: American Chemical Society

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8
Toward the First Class of Suicide Inhibitors of Kallikreins Involved in Skin Diseases
Toward the First Class of Suicide Inhibitors of Kallikreins Involved in Skin Diseases
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Toward the First Class of Suicide Inhibitors of Kallikreins Involved in Skin Diseases

Tan, Xiao ; Soualmia, Feryel ; Furio, Laetitia ; Renard, Jean-François ; Kempen, Isabelle ; Qin, Lixian ; Pagano, Maurice ; Pirotte, Bernard ; El Amri, Chahrazade ; Hovnanian, Alain ; Reboud-Ravaux, Michèle

Journal of medicinal chemistry, 2015-01, Vol.58 (2), p.598-612 [Periódico revisado por pares]

United States: American Chemical Society

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9
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
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Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

Meanwell, Nicholas A

Journal of medicinal chemistry, 2018-07, Vol.61 (14), p.5822-5880 [Periódico revisado por pares]

United States: American Chemical Society

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10
U.S. FDA Approved Drugs from 2015–June 2020: A Perspective
U.S. FDA Approved Drugs from 2015–June 2020: A Perspective
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U.S. FDA Approved Drugs from 2015–June 2020: A Perspective

Bhutani, Priyadeep ; Joshi, Gaurav ; Raja, Nivethitha ; Bachhav, Namrata ; Rajanna, Prabhakar K ; Bhutani, Hemant ; Paul, Atish T ; Kumar, Raj

Journal of medicinal chemistry, 2021-03, Vol.64 (5), p.2339-2381 [Periódico revisado por pares]

United States: American Chemical Society

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