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A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
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A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

Okazaki, Taku ; Chikuma, Shunsuke ; Iwai, Yoshiko ; Fagarasan, Sidonia ; Honjo, Tasuku

Nature immunology, 2013-12, Vol.14 (12), p.1212-1218 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
High proportion of PD‐1‐expressing CD4+ T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence
High proportion of PD‐1‐expressing CD4+ T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence
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High proportion of PD‐1‐expressing CD4+ T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence

Damouche, Abderaouf ; Pourcher, Guillaume ; Pourcher, Valérie ; Benoist, Stéphane ; Busson, Elodie ; Lataillade, Jean‐Jacques ; Van, Mélanie ; Lazure, Thierry ; Adam, Julien ; Favier, Benoit ; Vaslin, Bruno ; Müller‐Trutwin, Michaela ; Lambotte, Olivier ; Bourgeois, Christine

European journal of immunology, 2017-12, Vol.47 (12), p.2113-2123 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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3
Pembrolizumab versus Ipilimumab in Advanced Melanoma
Pembrolizumab versus Ipilimumab in Advanced Melanoma
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Pembrolizumab versus Ipilimumab in Advanced Melanoma

Robert, Caroline ; Schachter, Jacob ; Long, Georgina V ; Arance, Ana ; Grob, Jean Jacques ; Mortier, Laurent ; Daud, Adil ; Carlino, Matteo S ; McNeil, Catriona ; Lotem, Michal ; Larkin, James ; Lorigan, Paul ; Neyns, Bart ; Blank, Christian U ; Hamid, Omid ; Mateus, Christine ; Shapira-Frommer, Ronnie ; Kosh, Michele ; Zhou, Honghong ; Ibrahim, Nageatte ; Ebbinghaus, Scot ; Ribas, Antoni

The New England journal of medicine, 2015-06, Vol.372 (26), p.2521-2532 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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4
Structure and Interactions of the Human Programmed Cell Death 1 Receptor
Structure and Interactions of the Human Programmed Cell Death 1 Receptor
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Structure and Interactions of the Human Programmed Cell Death 1 Receptor

Cheng, Xiaoxiao ; Veverka, Vaclav ; Radhakrishnan, Anand ; Waters, Lorna C. ; Muskett, Frederick W. ; Morgan, Sara H. ; Huo, Jiandong ; Yu, Chao ; Evans, Edward J. ; Leslie, Alasdair J. ; Griffiths, Meryn ; Stubberfield, Colin ; Griffin, Robert ; Henry, Alistair J. ; Jansson, Andreas ; Ladbury, John E. ; Ikemizu, Shinji ; Carr, Mark D. ; Davis, Simon J.

The Journal of biological chemistry, 2013-04, Vol.288 (17), p.11771-11785 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation
Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation
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Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation

Chen, Nan ; Fang, Wenfeng ; Zhan, Jianhua ; Hong, Shaodong ; Tang, Yanna ; Kang, Shiyang ; Zhang, Yaxiong ; He, Xiaobo ; Zhou, Ting ; Qin, Tao ; Huang, Yan ; Yi, Xianping ; Zhang, Li

Journal of thoracic oncology, 2015-06, Vol.10 (6), p.910-923 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer
Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer
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Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer

Anagnostou, Valsamo ; Smith, Kellie N ; Forde, Patrick M ; Niknafs, Noushin ; Bhattacharya, Rohit ; White, James ; Zhang, Theresa ; Adleff, Vilmos ; Phallen, Jillian ; Wali, Neha ; Hruban, Carolyn ; Guthrie, Violeta B ; Rodgers, Kristen ; Naidoo, Jarushka ; Kang, Hyunseok ; Sharfman, William ; Georgiades, Christos ; Verde, Franco ; Illei, Peter ; Li, Qing Kay ; Gabrielson, Edward ; Brock, Malcolm V ; Zahnow, Cynthia A ; Baylin, Stephen B ; Scharpf, Robert B ; Brahmer, Julie R ; Karchin, Rachel ; Pardoll, Drew M ; Velculescu, Victor E

Cancer discovery, 2017-03, Vol.7 (3), p.264-276

United States

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7
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors
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Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

Lesko, Marta H. ; Miranda Rota, Enrique ; Dahan, Rony ; Georgiou, Andrew ; Sledzinska, Anna ; Werner Sunderland, Mariana ; Nicol, David ; Beers, Stephen A. ; Wotherspoon, Andrew ; Hayes, Andrew ; Stares, Mark ; Pickering, Lisa ; Rudman, Sarah ; Veeriah, Selvaraju ; Shafi, Seema ; Laycock, Joanne ; Bosshard-Carter, Leticia ; Goh, Gerald ; Rosenthal, Rachel ; Hynds, Robert E. ; Birkbak, Nicolai J. ; McGranahan, Nicholas ; Mitter, Richard ; Stewart, Aengus ; Rowan, Andrew ; Turajlic, Samra ; Abbosh, Christopher ; Goldman, Jacki ; Denner, Tamara ; Ward, Sophia ; Costa, Marta ; Lowe, Helen L. ; Lawrence, David ; Kolvekar, Shyam ; Falzon, Mary ; Simeon, Celia ; Hector, Gemma ; Novelli, Marco ; Forster, Martin ; Papadatos-Pastos, Dionysis ; Carnell, Dawn ; Navani, Neal ; Ahmed, Asia ; Taylor, Magali ; Choudhary, Junaid ; Taylor, Paul ; Rammohan, Kendadai ; Fontaine, Eustace ; Booton, Richard ; Moss, Stuart ; Idries, Faiza ; Joseph, Leena ; Moore, Katrina ; Waddington, Rachael ; Novasio, Juliette ; Blackhall, Fiona ; Rogan, Jane ; Tugwood, Jonathan ; Rothwell, Dominic G. ; Pierce, Jackie ; Gulati, Sakshi ; Kerr, Amy ; Webb, Joanne ; Moore, David ; Monteiro, William ; Marshall, Hilary ; Nelson, Louise ; Amadi, Anita ; Remmen, Hardy ; Miller, Joy ; Morgan, Fiona ; Kornaszewska, Malgorzata ; Bell, Harriet ; Smith, Sean ; Johnson, Benjamin ; Lim, Eric ; Barbosa, Monica Tavares ; Bowman, Alex ; Ronquillo, John Carlo ; Bhayani, Harshil ; Hamilton, Morag ; Bakar, Yusura ; Mensah, Natalie ; Buderi, Silviu ; Finch, Jonathan ; Green, Sophie ; Nicholson, Andrew G. ; Lau, Kelvin ; Schmid, Peter ; Conibear, John ; Ezhil, Veni ; Ismail, Babikir ; Prakash, Vineet ; Horey, Tracey ; Swanton, Charles ; Chester, Kerry A. ; Ravetch, Jeffrey V. ; Marafioti, Teresa ; Peggs, Karl S. ; Quezada, Sergio A.

Immunity (Cambridge, Mass.), 2017-04, Vol.46 (4), p.577-586 [Periódico revisado por pares]

United States: Elsevier Inc

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8
A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
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A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

Łuksza, Marta ; Riaz, Nadeem ; Makarov, Vladimir ; Balachandran, Vinod P ; Hellmann, Matthew D ; Solovyov, Alexander ; Rizvi, Naiyer A ; Merghoub, Taha ; Levine, Arnold J ; Chan, Timothy A ; Wolchok, Jedd D ; Greenbaum, Benjamin D

Nature (London), 2017-11, Vol.551 (7681), p.517-520 [Periódico revisado por pares]

England: Nature Publishing Group

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9
PD-L2 Expression in Human Tumors: Relevance to Anti-PD-1 Therapy in Cancer
PD-L2 Expression in Human Tumors: Relevance to Anti-PD-1 Therapy in Cancer
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PD-L2 Expression in Human Tumors: Relevance to Anti-PD-1 Therapy in Cancer

Yearley, Jennifer H ; Gibson, Christopher ; Yu, Ni ; Moon, Christina ; Murphy, Erin ; Juco, Jonathan ; Lunceford, Jared ; Cheng, Jonathan ; Chow, Laura Q M ; Seiwert, Tanguy Y ; Handa, Masahisa ; Tomassini, Joanne E ; McClanahan, Terrill

Clinical cancer research, 2017-06, Vol.23 (12), p.3158-3167 [Periódico revisado por pares]

United States: American Association for Cancer Research Inc

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10
Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization
Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization
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Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization

Pesce, Silvia, PhD ; Greppi, Marco ; Tabellini, Giovanna, PhD ; Rampinelli, Fabio, MD ; Parolini, Silvia, PhD ; Olive, Daniel, MD ; Moretta, Lorenzo, MD ; Moretta, Alessandro, MD ; Marcenaro, Emanuela, PhD

Journal of allergy and clinical immunology, 2017-01, Vol.139 (1), p.335-346.e3 [Periódico revisado por pares]

United States: Elsevier Inc

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