Cemiplimab monotherapy for first-line treatment of advanced non-small-cell lung cancer with PD-L1 of at least 50%: a multicentre, open-label, global, phase 3, randomised, controlled trial

Sezer, Ahmet ; Kilickap, Saadettin ; Gümüş, Mahmut ; Bondarenko, Igor ; Özgüroğlu, Mustafa ; Gogishvili, Miranda ; Turk, Haci M ; Cicin, Irfan ; Bentsion, Dmitry ; Gladkov, Oleg ; Clingan, Philip ; Sriuranpong, Virote ; Rizvi, Naiyer ; Gao, Bo ; Li, Siyu ; Lee, Sue ; McGuire, Kristina ; Chen, Chieh-I ; Makharadze, Tamta ; Paydas, Semra ; Nechaeva, Marina ; Seebach, Frank ; Weinreich, David M ; Yancopoulos, George D ; Gullo, Giuseppe ; Lowy, Israel ; Rietschel, Petra

England: Elsevier Ltd

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Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial

Gogishvili, Miranda ; Melkadze, Tamar ; Makharadze, Tamta ; Giorgadze, Davit ; Dvorkin, Mikhail ; Penkov, Konstantin ; Laktionov, Konstantin ; Nemsadze, Gia ; Nechaeva, Marina ; Rozhkova, Irina ; Kalinka, Ewa ; Gessner, Christian ; Moreno-Jaime, Brizio ; Passalacqua, Rodolfo ; Li, Siyu ; McGuire, Kristina ; Kaul, Manika ; Paccaly, Anne ; Quek, Ruben G W ; Gao, Bo ; Seebach, Frank ; Weinreich, David M ; Yancopoulos, George D ; Lowy, Israel ; Gullo, Giuseppe ; Rietschel, Petra

United States: Nature Publishing Group

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A phase 1/2 study of REGN4336, a PSMAxCD3 bispecific antibody, alone and in combination with cemiplimab in patients with metastatic castration-resistant prostate cancer

Kelly, William Kevin ; Thanigaimani, Pradeep ; Sun, Furong ; Seebach, Frank A. ; Lowy, Israel ; Sandigursky, Sabina ; Miller, Elizabeth

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PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma

Migden, Michael R ; Rischin, Danny ; Schmults, Chrysalyne D ; Guminski, Alexander ; Hauschild, Axel ; Lewis, Karl D ; Chung, Christine H ; Hernandez-Aya, Leonel ; Lim, Annette M ; Chang, Anne Lynn S ; Rabinowits, Guilherme ; Thai, Alesha A ; Dunn, Lara A ; Hughes, Brett G.M ; Khushalani, Nikhil I ; Modi, Badri ; Schadendorf, Dirk ; Gao, Bo ; Seebach, Frank ; Li, Siyu ; Li, Jingjin ; Mathias, Melissa ; Booth, Jocelyn ; Mohan, Kosalai ; Stankevich, Elizabeth ; Babiker, Hani M ; Brana, Irene ; Gil-Martin, Marta ; Homsi, Jade ; Johnson, Melissa L ; Moreno, Victor ; Niu, Jiaxin ; Owonikoko, Taofeek K ; Papadopoulos, Kyriakos P ; Yancopoulos, George D ; Lowy, Israel ; Fury, Matthew G

United States: Massachusetts Medical Society

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Survival with Cemiplimab in Recurrent Cervical Cancer

Tewari, Krishnansu S ; Monk, Bradley J ; Vergote, Ignace ; Miller, Austin ; de Melo, Andreia C ; Kim, Hee-Seung ; Kim, Yong Man ; Lisyanskaya, Alla ; Samouëlian, Vanessa ; Lorusso, Domenica ; Damian, Fernanda ; Chang, Chih-Long ; Gotovkin, Evgeniy A ; Takahashi, Shunji ; Ramone, Daniella ; Pikiel, Joanna ; Maćkowiak-Matejczyk, Beata ; Guerra Alía, Eva M ; Colombo, Nicoletta ; Makarova, Yulia ; Rischin, Danny ; Lheureux, Stephanie ; Hasegawa, Kosei ; Fujiwara, Keiichi ; Li, Jingjin ; Jamil, Shaheda ; Jankovic, Vladimir ; Chen, Chieh-I ; Seebach, Frank ; Weinreich, David M ; Yancopoulos, George D ; Lowy, Israel ; Mathias, Melissa ; Fury, Matthew G ; Oaknin, Ana

United States: Massachusetts Medical Society

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A phase 1/2 study of REGN4336, a PSMAxCD3 bispecific antibody, alone and in combination with cemiplimab in patients with metastatic castration-resistant prostate cancer

Kelly, William Kevin ; Hussain, Arif ; Saraiya, Biren ; Thanigaimani, Pradeep ; Sun, Furong ; Seebach, Frank A. ; Lowy, Israel ; Sandigursky, Sabina ; Miller, Elizabeth

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Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma

Gross, Neil D. ; Miller, David M. ; Khushalani, Nikhil I. ; Divi, Vasu ; Ruiz, Emily S. ; Lipson, Evan J. ; Meier, Friedegund ; Su, Yungpo B. ; Swiecicki, Paul L. ; Atlas, Jennifer ; Geiger, Jessica L. ; Hauschild, Axel ; Choe, Jennifer H. ; Hughes, Brett G.M. ; Schadendorf, Dirk ; Patel, Vishal A. ; Homsi, Jade ; Taube, Janis M. ; Lim, Annette M. ; Ferrarotto, Renata ; Kaufman, Howard L. ; Seebach, Frank ; Lowy, Israel ; Yoo, Suk-Young ; Mathias, Melissa ; Fenech, Keilah ; Han, Hyunsil ; Fury, Matthew G. ; Rischin, Danny

United States: Massachusetts Medical Society

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A phase I/II study of REGN5093, a MET x MET bispecific antibody, in patients with MET-altered advanced non-small cell lung cancer (NSCLC)

Rowlands, Tracey ; Boyapati, Anita ; Li, Siyu ; Daly, Christopher ; Seebach, Frank A. ; Lowy, Israel ; Rietschel, Petra

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A phase 1/2 study of REGN7075 (EGFRxCD28 costimulatory bispecific antibody) in combination with cemiplimab (anti–PD-1) in patients with advanced solid tumors, including colorectal cancer: Trial in progress update

Segal, Neil Howard ; Girda, Eugenia ; Sohal, Davendra ; Lakhani, Nehal J. ; Olszanski, Anthony J. ; Fong, Lawrence ; Han, Hyunsil ; Casey, Kerry A. ; Li, Siyu ; Ganguly, Samit ; Seebach, Frank A. ; Mathias, Melissa Divya ; Pelster, Meredith

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Preliminary results from a phase 1/2 study of co-stimulatory bispecific PSMAxCD28 antibody REGN5678 in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)

Stein, Mark N. ; Zhang, Jingsong ; Kelly, William Kevin ; Wise, David R ; Tsao, Kai ; Carneiro, Benedito A. ; Falchook, Gerald Steven ; Sun, Furong ; Govindraj, Shilpa ; Sims, Jennifer S ; Zhu, Min ; Seebach, Frank A. ; Lowy, Israel ; Thanigaimani, Pradeep ; Sandigursky, Sabina ; Miller, Elizabeth

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