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41
Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model
Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model
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Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

Clayton, Kevin ; Delpech, Jean Christophe ; Herron, Shawn ; Iwahara, Naotoshi ; Ericsson, Maria ; Saito, Takashi ; Saido, Takaomi C ; Ikezu, Seiko ; Ikezu, Tsuneya

Molecular neurodegeneration, 2021-03, Vol.16 (1), p.18-18, Article 18 [Periódico revisado por pares]

England: BioMed Central

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42
RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease
RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease
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RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease

Bishof, Isaac ; Dammer, Eric B. ; Duong, Duc M. ; Kundinger, Sean R. ; Gearing, Marla ; Lah, James J. ; Levey, Allan I. ; Seyfried, Nicholas T.

The Journal of biological chemistry, 2018-07, Vol.293 (28), p.11047-11066 [Periódico revisado por pares]

United States: Elsevier Inc

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43
A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications
A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications
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A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications

Drepper, Friedel ; Biernat, Jacek ; Kaniyappan, Senthilvelrajan ; Meyer, Helmut E. ; Mandelkow, Eva Maria ; Warscheid, Bettina ; Mandelkow, Eckhard

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.18213-18225 [Periódico revisado por pares]

United States: Elsevier Inc

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44
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
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Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

Arakhamia, Tamta ; Lee, Christina E. ; Carlomagno, Yari ; Kumar, Mukesh ; Duong, Duc M. ; Wesseling, Hendrik ; Kundinger, Sean R. ; Wang, Kevin ; Williams, Dewight ; DeTure, Michael ; Dickson, Dennis W. ; Cook, Casey N. ; Seyfried, Nicholas T. ; Petrucelli, Leonard ; Steen, Judith A. ; Fitzpatrick, Anthony W.P.

Cell, 2020-02, Vol.180 (4), p.633-644.e12 [Periódico revisado por pares]

United States: Elsevier Inc

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45
Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions
Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions
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Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions

Petry, Franck R ; Pelletier, Jérôme ; Bretteville, Alexis ; Morin, Françoise ; Calon, Frédéric ; Hébert, Sébastien S ; Whittington, Robert A ; Planel, Emmanuel Avila, Jesus

PloS one, 2014-05, Vol.9 (5), p.e94251-e94251 [Periódico revisado por pares]

United States: Public Library of Science

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46
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases
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Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases

Zhang, Wenjuan ; Falcon, Benjamin ; Murzin, Alexey G ; Fan, Juan ; Crowther, R Anthony ; Goedert, Michel ; Scheres, Sjors Hw

eLife, 2019-02, Vol.8 [Periódico revisado por pares]

England: eLife Sciences Publications Ltd

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47
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation
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Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation

McEwan, William A. ; Falcon, Benjamin ; Vaysburd, Marina ; Clift, Dean ; Oblak, Adrian L. ; Ghetti, Bernardino ; Goedert, Michel ; James, Leo C.

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (3), p.574-579 [Periódico revisado por pares]

United States: National Academy of Sciences

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48
Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells
Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells
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Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells

Woerman, Amanda L. ; Aoyagi, Atsushi ; Patel, Smita ; Kazmi, Sabeen A. ; Lobach, Iryna ; Grinberg, Lea T. ; McKee, Ann C. ; Seeley, William W. ; Olson, Steven H. ; Prusiner, Stanley B.

Proceedings of the National Academy of Sciences - PNAS, 2016-12, Vol.113 (50), p.E8187-E8196 [Periódico revisado por pares]

United States: National Academy of Sciences

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49
Microtubule affinity–regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration
Microtubule affinity–regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration
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Microtubule affinity–regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration

Oba, Toshiya ; Saito, Taro ; Asada, Akiko ; Shimizu, Sawako ; Iijima, Koichi M. ; Ando, Kanae

The Journal of biological chemistry, 2020-12, Vol.295 (50), p.17138-17147 [Periódico revisado por pares]

United States: Elsevier Inc

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50
Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation
Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation
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Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

Chen, John J. ; Nathaniel, Diane L. ; Raghavan, Preethi ; Nelson, Maxine ; Tian, Ruilin ; Tse, Eric ; Hong, Jason Y. ; See, Stephanie K. ; Mok, Sue-Ann ; Hein, Marco Y. ; Southworth, Daniel R. ; Grinberg, Lea T. ; Gestwicki, Jason E. ; Leonetti, Manuel D. ; Kampmann, Martin

The Journal of biological chemistry, 2019-12, Vol.294 (50), p.18952-18966 [Periódico revisado por pares]

United States: Elsevier Inc

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