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Structures of filaments from Pick's disease reveal a novel tau protein fold
Structures of filaments from Pick's disease reveal a novel tau protein fold
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Structures of filaments from Pick's disease reveal a novel tau protein fold

Falcon, Benjamin ; Zhang, Wenjuan ; Murzin, Alexey G ; Murshudov, Garib ; Garringer, Holly J ; Vidal, Ruben ; Crowther, R Anthony ; Ghetti, Bernardino ; Scheres, Sjors H W ; Goedert, Michel

Nature (London), 2018-09, Vol.561 (7721), p.137-140 [Periódico revisado por pares]

England: Nature Publishing Group

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12
A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein
A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein
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A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein

Mortelecque, Justine ; Zejneli, Orgeta ; Bégard, Séverine ; Simões, Margarida C. ; ElHajjar, Lea ; Nguyen, Marine ; Cantrelle, François-Xavier ; Hanoulle, Xavier ; Rain, Jean-Christophe ; Colin, Morvane ; Gomes, Cláudio M. ; Buée, Luc ; Landrieu, Isabelle ; Danis, Clément ; Dupré, Elian

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107163-107163, Article 107163 [Periódico revisado por pares]

United States: Elsevier Inc

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13
Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture
Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture
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Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture

Zempel, Hans ; Dennissen, Frank J.A. ; Kumar, Yatender ; Luedtke, Julia ; Biernat, Jacek ; Mandelkow, Eva-Maria ; Mandelkow, Eckhard

The Journal of biological chemistry, 2017-07, Vol.292 (29), p.12192-12207 [Periódico revisado por pares]

United States: Elsevier Inc

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14
Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn‐mediated local protein translation
Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn‐mediated local protein translation
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Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn‐mediated local protein translation

Li, Chuanzhou ; Götz, Jürgen

The EMBO journal, 2017-11, Vol.36 (21), p.3120-3138 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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15
Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies
Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies
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Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies

Strang, Kevin H. ; Croft, Cara L. ; Sorrentino, Zachary A. ; Chakrabarty, Paramita ; Golde, Todd E. ; Giasson, Benoit I.

The Journal of biological chemistry, 2018-02, Vol.293 (7), p.2408-2421 [Periódico revisado por pares]

United States: Elsevier Inc

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16
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice
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In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice

Yamada, Kaoru ; Cirrito, John R ; Stewart, Floy R ; Jiang, Hong ; Finn, Mary Beth ; Holmes, Brandon B ; Binder, Lester I ; Mandelkow, Eva-Maria ; Diamond, Marc I ; Lee, Virginia M-Y ; Holtzman, David M

The Journal of neuroscience, 2011-09, Vol.31 (37), p.13110-13117 [Periódico revisado por pares]

United States: Society for Neuroscience

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17
Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
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Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons

Wu, Jessica W. ; Herman, Mathieu ; Liu, Li ; Simoes, Sabrina ; Acker, Christopher M. ; Figueroa, Helen ; Steinberg, Joshua I. ; Margittai, Martin ; Kayed, Rakez ; Zurzolo, Chiara ; Di Paolo, Gilbert ; Duff, Karen E.

The Journal of biological chemistry, 2013-01, Vol.288 (3), p.1856-1870 [Periódico revisado por pares]

United States: Elsevier Inc

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18
Galectin-8–mediated selective autophagy protects against seeded tau aggregation
Galectin-8–mediated selective autophagy protects against seeded tau aggregation
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Galectin-8–mediated selective autophagy protects against seeded tau aggregation

Falcon, Benjamin ; Noad, Jessica ; McMahon, Harvey ; Randow, Felix ; Goedert, Michel

The Journal of biological chemistry, 2018-02, Vol.293 (7), p.2438-2451 [Periódico revisado por pares]

United States: Elsevier Inc

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19
Structure-based classification of tauopathies
Structure-based classification of tauopathies
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Structure-based classification of tauopathies

Shi, Yang ; Zhang, Wenjuan ; Yang, Yang ; Murzin, Alexey G ; Falcon, Benjamin ; Kotecha, Abhay ; van Beers, Mike ; Tarutani, Airi ; Kametani, Fuyuki ; Garringer, Holly J ; Vidal, Ruben ; Hallinan, Grace I ; Lashley, Tammaryn ; Saito, Yuko ; Murayama, Shigeo ; Yoshida, Mari ; Tanaka, Hidetomo ; Kakita, Akiyoshi ; Ikeuchi, Takeshi ; Robinson, Andrew C ; Mann, David M A ; Kovacs, Gabor G ; Revesz, Tamas ; Ghetti, Bernardino ; Hasegawa, Masato ; Goedert, Michel ; Scheres, Sjors H W

Nature (London), 2021-10, Vol.598 (7880), p.359-363 [Periódico revisado por pares]

England: Nature Publishing Group

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20
Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies
Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies
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Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies

Chang, Che-Wei ; Shao, Eric ; Mucke, Lennart

Science (American Association for the Advancement of Science), 2021-02, Vol.371 (6532) [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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