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1
Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo
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Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo

Ma, Yuan ; Zhao, Wenting ; Li, Yiding ; Pan, Yufei ; Wang, Shuhe ; Zhu, Yuejie ; Kong, Lingxuan ; Guan, Zhu ; Wang, Jiancheng ; Zhang, Lihe ; Yang, Zhenjun

Biomaterials, 2019-03, Vol.197, p.182-193 [Periódico revisado por pares]

Netherlands: Elsevier Ltd

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2
Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers
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Artigo
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Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers

Crooke, Stanley T ; Baker, Brenda F ; Kwoh, T Jesse ; Cheng, Wei ; Schulz, Dan J ; Xia, Shuting ; Salgado, Nelson ; Bui, Huynh-Hoa ; Hart, Christopher E ; Burel, Sebastien A ; Younis, Husam S ; Geary, Richard S ; Henry, Scott P ; Bhanot, Sanjay

Molecular therapy, 2016-10, Vol.24 (10), p.1771-1782 [Periódico revisado por pares]

United States: Elsevier Inc

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3
The Effects of 2′-O-Methoxyethyl Containing Antisense Oligonucleotides on Platelets in Human Clinical Trials
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The Effects of 2′-O-Methoxyethyl Containing Antisense Oligonucleotides on Platelets in Human Clinical Trials

Crooke, Stanley T. ; Baker, Brenda F. ; Witztum, Joseph L. ; Kwoh, T. Jesse ; Pham, Nguyen C. ; Salgado, Nelson ; McEvoy, Bradley W. ; Cheng, Wei ; Hughes, Steven G. ; Bhanot, Sanjay ; Geary, Richard S.

Nucleic acid therapeutics, 2017-06, Vol.27 (3), p.121-129 [Periódico revisado por pares]

United States: Mary Ann Liebert, Inc

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4
Concentrations of 6-Thioguanine Nucleotide Correlate With Trough Levels of Infliximab in Patients With Inflammatory Bowel Disease on Combination Therapy
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Concentrations of 6-Thioguanine Nucleotide Correlate With Trough Levels of Infliximab in Patients With Inflammatory Bowel Disease on Combination Therapy

Yarur, Andres J ; Kubiliun, Maddie J ; Czul, Frank ; Sussman, Daniel A ; Quintero, Maria A ; Jain, Anjali ; Drake, Katherine A ; Hauenstein, Scott I ; Lockton, Steven ; Deshpande, Amar R ; Barkin, Jamie S ; Singh, Sharat ; Abreu, Maria T

Clinical gastroenterology and hepatology, 2015-06, Vol.13 (6), p.1118-1124.e3 [Periódico revisado por pares]

United States: Elsevier Inc

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5
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
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N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells

Richartz, Nina ; Pietka, Wojciech ; Yadav, Ajay ; Bostad, Monica ; Bhagwat, Sampada ; Naderi, Soheil ; Naderi, Elin Hallan ; Stokke, Trond ; Ruud, Ellen ; Blomhoff, Heidi Kiil

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105509-105509, Article 105509 [Periódico revisado por pares]

United States: American Society for Biochemistry and Molecular Biology

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6
A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects
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A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects

Edwards, Alena Y. ; Elgart, Anna ; Farrell, Colm ; Barnett‐Griness, Ofra ; Rabinovich‐Guilatt, Laura ; Spiegelstein, Ofer

British journal of clinical pharmacology, 2017-09, Vol.83 (9), p.1932-1943 [Periódico revisado por pares]

England: John Wiley and Sons Inc

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7
NUDT15 R139C-related thiopurine leukocytopenia is mediated by 6-thioguanine nucleotide-independent mechanism in Japanese patients with inflammatory bowel disease
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NUDT15 R139C-related thiopurine leukocytopenia is mediated by 6-thioguanine nucleotide-independent mechanism in Japanese patients with inflammatory bowel disease

Asada, Ayumi ; Nishida, Atsushi ; Shioya, Makoto ; Imaeda, Hirotsugu ; Inatomi, Osamu ; Bamba, Shigeki ; Kito, Katsuyuki ; Sugimoto, Mitsushige ; Andoh, Akira

Journal of gastroenterology, 2016-01, Vol.51 (1), p.22-29 [Periódico revisado por pares]

Tokyo: Springer Japan

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8
Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo
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Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo

Hartmann, Gunther ; Weeratna, Risini D ; Ballas, Zuhair K ; Payette, Paul ; Blackwell, Sue ; Suparto, Irma ; Rasmussen, Wendy L ; Waldschmidt, Marianella ; Sajuthi, Dondin ; Purcell, Robert H ; Davis, Heather L ; Krieg, Arthur M

The Journal of immunology (1950), 2000-02, Vol.164 (3), p.1617-1624 [Periódico revisado por pares]

United States: Am Assoc Immnol

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9
Amb a 1–immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response
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Amb a 1–immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response

Tulic, Meri K ; Fiset, Pierre-Olivier ; Christodoulopoulos, Pota ; Vaillancourt, Patrice ; Desrosiers, Martin ; Lavigne, François ; Eiden, Joseph ; Hamid, Qutayba

Journal of allergy and clinical immunology, 2004-02, Vol.113 (2), p.235-241 [Periódico revisado por pares]

New York, NY: Mosby, Inc

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10
Highly sensitive and rapid determination of azathioprine metabolites in whole blood lysate by liquid chromatography–tandem mass spectrometry
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Highly sensitive and rapid determination of azathioprine metabolites in whole blood lysate by liquid chromatography–tandem mass spectrometry

Miao, Qiang ; Bai, Yang-Juan ; Zhang, Jun-Long ; Li, Yi ; Su, Zhen-Zhen ; Yan, Lin ; Wang, Lan-Lan ; Zou, Yuan-Gao

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-01, Vol.1136, p.121802, Article 121802 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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