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1
Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers
Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers
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Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers

Crooke, Stanley T ; Baker, Brenda F ; Kwoh, T Jesse ; Cheng, Wei ; Schulz, Dan J ; Xia, Shuting ; Salgado, Nelson ; Bui, Huynh-Hoa ; Hart, Christopher E ; Burel, Sebastien A ; Younis, Husam S ; Geary, Richard S ; Henry, Scott P ; Bhanot, Sanjay

Molecular therapy, 2016-10, Vol.24 (10), p.1771-1782 [Periódico revisado por pares]

United States: Elsevier Inc

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2
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
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N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells

Richartz, Nina ; Pietka, Wojciech ; Yadav, Ajay ; Bostad, Monica ; Bhagwat, Sampada ; Naderi, Soheil ; Naderi, Elin Hallan ; Stokke, Trond ; Ruud, Ellen ; Blomhoff, Heidi Kiil

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105509-105509, Article 105509 [Periódico revisado por pares]

United States: American Society for Biochemistry and Molecular Biology

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3
In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides
In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides
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In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Southwell, Amber L ; Skotte, Niels H ; Kordasiewicz, Holly B ; Østergaard, Michael E ; Watt, Andrew T ; Carroll, Jeffrey B ; Doty, Crystal N ; Villanueva, Erika B ; Petoukhov, Eugenia ; Vaid, Kuljeet ; Xie, Yuanyun ; Freier, Susan M ; Swayze, Eric E ; Seth, Punit P ; Bennett, Clarence Frank ; Hayden, Michael R

Molecular therapy, 2014-12, Vol.22 (12), p.2093-2106 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Perinuclear positioning of endosomes can affect PS-ASO activities
Perinuclear positioning of endosomes can affect PS-ASO activities
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Perinuclear positioning of endosomes can affect PS-ASO activities

Liang, Xue-hai ; Nichols, Joshua G ; Tejera, Dario ; Crooke, Stanley T

Nucleic acids research, 2021-12, Vol.49 (22), p.12970-12985 [Periódico revisado por pares]

England: Oxford University Press

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5
Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival
Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival
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Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival

Zhang, Fan ; Kumano, Masafumi ; Beraldi, Eliana ; Fazli, Ladan ; Du, Caigan ; Moore, Susan ; Sorensen, Poul ; Zoubeidi, Amina ; Gleave, Martin E

Nature communications, 2014-12, Vol.5 (1), p.5775-5775, Article 5775 [Periódico revisado por pares]

England: Nature Publishing Group

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6
A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects
A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects
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A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects

Edwards, Alena Y. ; Elgart, Anna ; Farrell, Colm ; Barnett‐Griness, Ofra ; Rabinovich‐Guilatt, Laura ; Spiegelstein, Ofer

British journal of clinical pharmacology, 2017-09, Vol.83 (9), p.1932-1943 [Periódico revisado por pares]

England: John Wiley and Sons Inc

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7
Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies
Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies
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Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies

Wang, Yulian ; Pang, Jiayun ; Wang, Qingyun ; Yan, Luocheng ; Wang, Lintao ; Xing, Zhen ; Wang, Chunming ; Zhang, Junfeng ; Dong, Lei

Advanced science, 2021-07, Vol.8 (13), p.2004929-n/a [Periódico revisado por pares]

Germany: John Wiley & Sons, Inc

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8
FDA-Approved Oligonucleotide Therapies in 2017
FDA-Approved Oligonucleotide Therapies in 2017
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FDA-Approved Oligonucleotide Therapies in 2017

Stein, Cy A. ; Castanotto, Daniela

Molecular therapy, 2017-05, Vol.25 (5), p.1069-1075 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2′‐O‐methyl RNA, phosphorothioates and small interfering RNA
Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2′‐O‐methyl RNA, phosphorothioates and small interfering RNA
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Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2′‐O‐methyl RNA, phosphorothioates and small interfering RNA

Grünweller, Arnold ; Wyszko, Eliza ; Bieber, Birgit ; Jahnel, Ricarda ; Erdmann, Volker A. ; Kurreck, Jens

Nucleic acids research, 2003-06, Vol.31 (12), p.3185-3193 [Periódico revisado por pares]

England: Oxford University Press

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10
Phosphorothioate DNA as an antioxidant in bacteria
Phosphorothioate DNA as an antioxidant in bacteria
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Phosphorothioate DNA as an antioxidant in bacteria

Xie, Xinqiang ; Liang, Jingdan ; Pu, Tianning ; Xu, Fei ; Yao, Fen ; Yang, Yan ; Zhao, Yi-Lei ; You, Delin ; Zhou, Xiufen ; Deng, Zixin ; Wang, Zhijun

Nucleic acids research, 2012-10, Vol.40 (18), p.9115-9124 [Periódico revisado por pares]

England: Oxford University Press

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