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11
Structure and Gating Behavior of the Human Integral Membrane Protein VDAC1 in a Lipid Bilayer
Structure and Gating Behavior of the Human Integral Membrane Protein VDAC1 in a Lipid Bilayer
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Structure and Gating Behavior of the Human Integral Membrane Protein VDAC1 in a Lipid Bilayer

Najbauer, Eszter E ; Tekwani Movellan, Kumar ; Giller, Karin ; Benz, Roland ; Becker, Stefan ; Griesinger, Christian ; Andreas, Loren B

Journal of the American Chemical Society, 2022-02, Vol.144 (7), p.2953-2967 [Periódico revisado por pares]

United States: American Chemical Society

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12
Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial
Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial
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Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial

Beer, Tomasz M ; Hotte, Sebastien J ; Saad, Fred ; Alekseev, Boris ; Matveev, Vsevolod ; Fléchon, Aude ; Gravis, Gwenaelle ; Joly, Florence ; Chi, Kim N ; Malik, Zafar ; Blumenstein, Brent ; Stewart, Patricia S ; Jacobs, Cindy A ; Fizazi, Karim

The lancet oncology, 2017-11, Vol.18 (11), p.1532-1542 [Periódico revisado por pares]

England: Elsevier Ltd

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13
ANTISENSE OLIGONUCLEOTIDES: FROM DESIGN TO THERAPEUTIC APPLICATION
ANTISENSE OLIGONUCLEOTIDES: FROM DESIGN TO THERAPEUTIC APPLICATION
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ANTISENSE OLIGONUCLEOTIDES: FROM DESIGN TO THERAPEUTIC APPLICATION

Chan, Jasmine HP ; Lim, Shuhui ; Wong, WS Fred

Clinical and experimental pharmacology & physiology, 2006-05, Vol.33 (5-6), p.533-540 [Periódico revisado por pares]

Melbourne, Australia: Blackwell Publishing Asia

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14
Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats
Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats
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Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats

Geary, R S ; Watanabe, T A ; Truong, L ; Freier, S ; Lesnik, E A ; Sioufi, N B ; Sasmor, H ; Manoharan, M ; Levin, A A

The Journal of pharmacology and experimental therapeutics, 2001-03, Vol.296 (3), p.890-897 [Periódico revisado por pares]

United States

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15
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
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N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells

Richartz, Nina ; Pietka, Wojciech ; Yadav, Ajay ; Bostad, Monica ; Bhagwat, Sampada ; Naderi, Soheil ; Naderi, Elin Hallan ; Stokke, Trond ; Ruud, Ellen ; Blomhoff, Heidi Kiil

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105509-105509, Article 105509 [Periódico revisado por pares]

United States: American Society for Biochemistry and Molecular Biology

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16
In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides
In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides
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In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Southwell, Amber L ; Skotte, Niels H ; Kordasiewicz, Holly B ; Østergaard, Michael E ; Watt, Andrew T ; Carroll, Jeffrey B ; Doty, Crystal N ; Villanueva, Erika B ; Petoukhov, Eugenia ; Vaid, Kuljeet ; Xie, Yuanyun ; Freier, Susan M ; Swayze, Eric E ; Seth, Punit P ; Bennett, Clarence Frank ; Hayden, Michael R

Molecular therapy, 2014-12, Vol.22 (12), p.2093-2106 [Periódico revisado por pares]

United States: Elsevier Inc

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17
Perinuclear positioning of endosomes can affect PS-ASO activities
Perinuclear positioning of endosomes can affect PS-ASO activities
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Perinuclear positioning of endosomes can affect PS-ASO activities

Liang, Xue-hai ; Nichols, Joshua G ; Tejera, Dario ; Crooke, Stanley T

Nucleic acids research, 2021-12, Vol.49 (22), p.12970-12985 [Periódico revisado por pares]

England: Oxford University Press

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18
Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival
Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival
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Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival

Zhang, Fan ; Kumano, Masafumi ; Beraldi, Eliana ; Fazli, Ladan ; Du, Caigan ; Moore, Susan ; Sorensen, Poul ; Zoubeidi, Amina ; Gleave, Martin E

Nature communications, 2014-12, Vol.5 (1), p.5775-5775, Article 5775 [Periódico revisado por pares]

England: Nature Publishing Group

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19
A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects
A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects
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A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects

Edwards, Alena Y. ; Elgart, Anna ; Farrell, Colm ; Barnett‐Griness, Ofra ; Rabinovich‐Guilatt, Laura ; Spiegelstein, Ofer

British journal of clinical pharmacology, 2017-09, Vol.83 (9), p.1932-1943 [Periódico revisado por pares]

England: John Wiley and Sons Inc

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20
Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies
Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies
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Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies

Wang, Yulian ; Pang, Jiayun ; Wang, Qingyun ; Yan, Luocheng ; Wang, Lintao ; Xing, Zhen ; Wang, Chunming ; Zhang, Junfeng ; Dong, Lei

Advanced science, 2021-07, Vol.8 (13), p.2004929-n/a [Periódico revisado por pares]

Germany: John Wiley & Sons, Inc

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