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Refinado por: Nome da Publicação: Clinical Pharmacology And Therapeutics remover assunto: Humans remover
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Appropriate Phenotyping Procedures for Drug Metabolizing Enzymes and Transporters in Humans and Their Simultaneous Use in the "Cocktail" Approach
Appropriate Phenotyping Procedures for Drug Metabolizing Enzymes and Transporters in Humans and Their Simultaneous Use in the "Cocktail" Approach
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Appropriate Phenotyping Procedures for Drug Metabolizing Enzymes and Transporters in Humans and Their Simultaneous Use in the "Cocktail" Approach

Fuhr, U ; Jetter, A ; Kirchheiner, J

Clinical pharmacology and therapeutics, 2007-02, Vol.81 (2), p.270-283 [Periódico revisado por pares]

New York, NY: Nature Publishing

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2
Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children
Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children
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Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children

Zhou, Wangda ; Johnson, Trevor N. ; Bui, Khanh H. ; Cheung, S.Y. Amy ; Li, Jianguo ; Xu, Hongmei ; Al‐Huniti, Nidal ; Zhou, Diansong

Clinical pharmacology and therapeutics, 2018-07, Vol.104 (1), p.188-200 [Periódico revisado por pares]

United States

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3
Chronological Effects of Rifampicin Discontinuation on Cytochrome P450 Activity in Healthy Japanese Volunteers, Using the Cocktail Method
Chronological Effects of Rifampicin Discontinuation on Cytochrome P450 Activity in Healthy Japanese Volunteers, Using the Cocktail Method
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Chronological Effects of Rifampicin Discontinuation on Cytochrome P450 Activity in Healthy Japanese Volunteers, Using the Cocktail Method

Inui, N ; Akamatsu, T ; Uchida, S ; Tanaka, S ; Namiki, N ; Karayama, M ; Chida, K ; Watanabe, H

Clinical pharmacology and therapeutics, 2013-12, Vol.94 (6), p.702-708 [Periódico revisado por pares]

Basingstoke: Blackwell Publishing Ltd

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4
Liver disease selectively modulates cytochrome P450-mediated metabolism
Liver disease selectively modulates cytochrome P450-mediated metabolism
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Liver disease selectively modulates cytochrome P450-mediated metabolism

Frye, Reginald F. ; Zgheib, Nathalie K. ; Matzke, Gary R. ; Chaves‐Gnecco, Diego ; Rabinovitz, Mordechai ; Shaikh, Obaid S. ; Branch, Robert A.

Clinical pharmacology and therapeutics, 2006-09, Vol.80 (3), p.235-245 [Periódico revisado por pares]

New York, NY: Nature Publishing

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5
Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2
Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2
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Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2

Granfors, Marika T. ; Backman, Janne T. ; Laitila, Jouko ; Neuvonen, Pertti J.

Clinical pharmacology and therapeutics, 2005-10, Vol.78 (4), p.400-411 [Periódico revisado por pares]

New York, NY: Nature Publishing

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6
Learning versus confirming in clinical drug development
Learning versus confirming in clinical drug development
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Learning versus confirming in clinical drug development

Sheiner, Lewis B.

Clinical pharmacology and therapeutics, 1997-03, Vol.61 (3), p.275-291 [Periódico revisado por pares]

New York, NY: Nature Publishing

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7
Multiple Dosing of Ephedra-Free Dietary Supplements: Hemodynamic, Electrocardiographic, and Bacterial Contamination Effects
Multiple Dosing of Ephedra-Free Dietary Supplements: Hemodynamic, Electrocardiographic, and Bacterial Contamination Effects
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Multiple Dosing of Ephedra-Free Dietary Supplements: Hemodynamic, Electrocardiographic, and Bacterial Contamination Effects

Foster, L ; Allan, M C ; Khan, A ; Moore, P ; Williams, D K ; Hubbard, M ; Dixon, L ; Gurley, B J

Clinical pharmacology and therapeutics, 2013-03, Vol.93 (3), p.267-274 [Periódico revisado por pares]

Basingstoke: Blackwell Publishing Ltd

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8
Sympathomimetic effects of paraxanthine and caffeine in humans
Sympathomimetic effects of paraxanthine and caffeine in humans
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Sympathomimetic effects of paraxanthine and caffeine in humans

Benowitz, Neal L. ; Jacob, Peyton ; Mayan, Haim ; Denaro, Charles

Clinical pharmacology and therapeutics, 1995-12, Vol.58 (6), p.684-691 [Periódico revisado por pares]

New York, NY: Nature Publishing

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9
Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use
Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use
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Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use

Haller, Christine A. ; Jacob, Peyton ; Benowitz, Neal L.

Clinical pharmacology and therapeutics, 2002-06, Vol.71 (6), p.421-432 [Periódico revisado por pares]

New York, NY: Nature Publishing

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10
Liver dysfunction markedly decreases the inhibition of cytochrome P450 1A2-mediated theophylline metabolism by fluvoxamine
Liver dysfunction markedly decreases the inhibition of cytochrome P450 1A2-mediated theophylline metabolism by fluvoxamine
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Liver dysfunction markedly decreases the inhibition of cytochrome P450 1A2-mediated theophylline metabolism by fluvoxamine

Orlando, Rocco ; Padrini, Roberto ; Perazzi, Mauro ; De Martin, Sara ; Piccoli, Pierpaolo ; Palatini, Pietro

Clinical pharmacology and therapeutics, 2006-05, Vol.79 (5), p.489-499 [Periódico revisado por pares]

New York, NY: Nature Publishing

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