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Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets
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Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

Zhao, Jing Hua ; Stacey, David ; Eriksson, Niclas ; Macdonald-Dunlop, Erin ; Hedman, Åsa K ; Kalnapenkis, Anette ; Enroth, Stefan ; Cozzetto, Domenico ; Digby-Bell, Jonathan ; Marten, Jonathan ; Folkersen, Lasse ; Herder, Christian ; Jonsson, Lina ; Bergen, Sarah E ; Gieger, Christian ; Needham, Elise J ; Surendran, Praveen ; Paul, Dirk S ; Polasek, Ozren ; Thorand, Barbara ; Grallert, Harald ; Roden, Michael ; Võsa, Urmo ; Esko, Tonu ; Hayward, Caroline ; Johansson, Åsa ; Gyllensten, Ulf ; Powell, Nick ; Hansson, Oskar ; Mattsson-Carlgren, Niklas ; Joshi, Peter K ; Danesh, John ; Padyukov, Leonid ; Klareskog, Lars ; Landén, Mikael ; Wilson, James F ; Siegbahn, Agneta ; Wallentin, Lars ; Mälarstig, Anders ; Butterworth, Adam S ; Peters, James E

Nature immunology, 2023-09, Vol.24 (9), p.1540-1551 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
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Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

Suri, Pradeep ; Palmer, Melody R ; Tsepilov, Yakov A ; Freidin, Maxim B ; Boer, Cindy G ; Yau, Michelle S ; Evans, Daniel S ; Gelemanovic, Andrea ; Bartz, Traci M ; Nethander, Maria ; Arbeeva, Liubov ; Karssen, Lennart ; Neogi, Tuhina ; Campbell, Archie ; Mellstrom, Dan ; Ohlsson, Claes ; Marshall, Lynn M ; Orwoll, Eric ; Uitterlinden, Andre ; Rotter, Jerome I ; Lauc, Gordan ; Psaty, Bruce M ; Karlsson, Magnus K ; Lane, Nancy E ; Jarvik, Gail P ; Polasek, Ozren ; Hochberg, Marc ; Jordan, Joanne M ; Van Meurs, Joyce B J ; Jackson, Rebecca ; Nielson, Carrie M ; Mitchell, Braxton D ; Smith, Blair H ; Hayward, Caroline ; Smith, Nicholas L ; Aulchenko, Yurii S ; Williams, Frances M K Loos, Ruth J. F.

PLoS genetics, 2018-09, Vol.14 (9), p.e1007601-e1007601 [Periódico revisado por pares]

United States: Public Library of Science

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3
Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension
Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension
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Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension

Ji, Yingjie ; Yiorkas, Andrianos M ; Frau, Francesca ; Mook-Kanamori, Dennis ; Staiger, Harald ; Thomas, E Louise ; Atabaki-Pasdar, Naeimeh ; Campbell, Archie ; Tyrrell, Jessica ; Jones, Samuel E ; Beaumont, Robin N ; Wood, Andrew R ; Tuke, Marcus A ; Ruth, Katherine S ; Mahajan, Anubha ; Murray, Anna ; Freathy, Rachel M ; Weedon, Michael N ; Hattersley, Andrew T ; Hayward, Caroline ; Machann, Jürgen ; Häring, Hans-Ulrich ; Franks, Paul ; de Mutsert, Renée ; Pearson, Ewan ; Stefan, Norbert ; Frayling, Timothy M ; Allebrandt, Karla V ; Bell, Jimmy D ; Blakemore, Alexandra I ; Yaghootkar, Hanieh

Diabetes (New York, N.Y.), 2019-01, Vol.68 (1), p.207-219 [Periódico revisado por pares]

United States: American Diabetes Association

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4
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation
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Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

Shen, Xia ; Klarić, Lucija ; Sharapov, Sodbo ; Mangino, Massimo ; Ning, Zheng ; Wu, Di ; Trbojević-Akmačić, Irena ; Pučić-Baković, Maja ; Rudan, Igor ; Polašek, Ozren ; Hayward, Caroline ; Spector, Timothy D ; Wilson, James F ; Lauc, Gordan ; Aulchenko, Yurii S

Nature communications, 2017-09, Vol.8 (1), p.447-10, Article 447 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Genetic Landscape of the ACE2 Coronavirus Receptor
Genetic Landscape of the ACE2 Coronavirus Receptor
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Genetic Landscape of the ACE2 Coronavirus Receptor

Yang, Zhijian ; Macdonald-Dunlop, Erin ; Chen, Jiantao ; Zhai, Ranran ; Li, Ting ; Richmond, Anne ; Klarić, Lucija ; Pirastu, Nicola ; Ning, Zheng ; Zheng, Chenqing ; Wang, Yipeng ; Huang, Tingting ; He, Yazhou ; Guo, Huiming ; Ying, Kejun ; Gustafsson, Stefan ; Prins, Bram ; Ramisch, Anna ; Dermitzakis, Emmanouil T ; Png, Grace ; Eriksson, Niclas ; Haessler, Jeffrey ; Hu, Xiaowei ; Zanetti, Daniela ; Boutin, Thibaud ; Hwang, Shih-Jen ; Wheeler, Eleanor ; Pietzner, Maik ; Raffield, Laura M ; Kalnapenkis, Anette ; Peters, James E ; Viñuela, Ana ; Gilly, Arthur ; Elmståhl, Sölve ; Dedoussis, George ; Petrie, John R ; Polašek, Ozren ; Folkersen, Lasse ; Chen, Yan ; Yao, Chen ; Võsa, Urmo ; Pairo-Castineira, Erola ; Clohisey, Sara ; Bretherick, Andrew D ; Rawlik, Konrad ; Esko, Tõnu ; Enroth, Stefan ; Johansson, Åsa ; Gyllensten, Ulf ; Langenberg, Claudia ; Levy, Daniel ; Hayward, Caroline ; Assimes, Themistocles L ; Kooperberg, Charles ; Manichaikul, Ani W ; Siegbahn, Agneta ; Wallentin, Lars ; Lind, Lars ; Zeggini, Eleftheria ; Schwenk, Jochen M ; Butterworth, Adam S ; Michaëlsson, Karl ; Pawitan, Yudi ; Joshi, Peter K ; Baillie, J Kenneth ; Mälarstig, Anders ; Reiner, Alexander P ; Wilson, James F ; Shen, Xia

Circulation (New York, N.Y.), 2022-05, Vol.145 (18), p.1398-1411 [Periódico revisado por pares]

United States: Lippincott Williams & Wilkins

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6
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease
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Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

Jakobsdottir, Johanna ; van der Lee, Sven J ; Bis, Joshua C ; Chouraki, Vincent ; Li-Kroeger, David ; Yamamoto, Shinya ; Grove, Megan L ; Naj, Adam ; Vronskaya, Maria ; Salazar, Jose L ; DeStefano, Anita L ; Brody, Jennifer A ; Smith, Albert V ; Amin, Najaf ; Sims, Rebecca ; Ibrahim-Verbaas, Carla A ; Choi, Seung-Hoan ; Satizabal, Claudia L ; Lopez, Oscar L ; Beiser, Alexa ; Ikram, M Arfan ; Garcia, Melissa E ; Hayward, Caroline ; Varga, Tibor V ; Ripatti, Samuli ; Franks, Paul W ; Hallmans, Göran ; Rolandsson, Olov ; Jansson, Jan-Håkon ; Porteous, David J ; Salomaa, Veikko ; Eiriksdottir, Gudny ; Rice, Kenneth M ; Bellen, Hugo J ; Levy, Daniel ; Uitterlinden, Andre G ; Emilsson, Valur ; Rotter, Jerome I ; Aspelund, Thor ; O'Donnell, Christopher J ; Fitzpatrick, Annette L ; Launer, Lenore J ; Hofman, Albert ; Wang, Li-San ; Williams, Julie ; Schellenberg, Gerard D ; Boerwinkle, Eric ; Psaty, Bruce M ; Seshadri, Sudha ; Shulman, Joshua M ; Gudnason, Vilmundur ; van Duijn, Cornelia M Haines, Jonathan L.

PLoS genetics, 2016-10, Vol.12 (10), p.e1006327 [Periódico revisado por pares]

United States: Public Library of Science

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7
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
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Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

Okbay, Aysu ; Wu, Yeda ; Wang, Nancy ; Jayashankar, Hariharan ; Bennett, Michael ; Nehzati, Seyed Moeen ; Sidorenko, Julia ; Kweon, Hyeokmoon ; Goldman, Grant ; Gjorgjieva, Tamara ; Jiang, Yunxuan ; Hicks, Barry ; Tian, Chao ; Hinds, David A ; Ahlskog, Rafael ; Magnusson, Patrik K. E ; Oskarsson, Sven ; Hayward, Caroline ; Campbell, Archie ; Porteous, David J ; Freese, Jeremy ; Herd, Pamela ; Watson, Chelsea ; Jala, Jonathan ; Conley, Dalton ; Koellinger, Philipp D ; Johannesson, Magnus ; Laibson, David ; Meyer, Michelle N ; Lee, James J ; Kong, Augustine ; Yengo, Loic ; Cesarini, David ; Turley, Patrick ; Visscher, Peter M ; Beauchamp, Jonathan P ; Benjamin, Daniel J ; Young, Alexander, I

Univ Edinburgh, Western Gen Hosp, Inst Genet & Canc, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland 2022

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8
Global Biobank Meta-analysis Initiative : Powering genetic discovery across human disease
Global Biobank Meta-analysis Initiative : Powering genetic discovery across human disease
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Global Biobank Meta-analysis Initiative : Powering genetic discovery across human disease

Zhou, Wei ; Kanai, Masahiro ; Rasheed, Humaira ; Wang, Ying ; Bhattacharya, Arjun ; Zhao, Huiling ; Namba, Shinichi ; Wolford, Brooke N ; Lo Faro, Valeria ; Lopera-Maya, Esteban A ; Lall, Kristi ; Fave, Marie-Julie ; Karjalainen, Juha ; Brumpton, Ben M ; Chavan, Sameer ; Chen, Tzu-Ting ; Daya, Michelle ; Ding, Yi ; Graham, Sarah E ; Hornsby, Whitney E ; Ismail, Said I ; Johnson, Ruth ; Laisk, Triin ; Lin, Kuang ; Lv, Jun ; Palta, Priit ; Pandit, Anita ; Preuss, Michael H ; Saad, Chadi ; Thorsteinsdottir, Unnur ; Verma, Anurag ; Zhong, Xue ; Al-Dabhani, Kawthar M ; Campbell, Archie ; Crooks, Kristy ; de Bock, Geertruida H ; Damrauer, Scott M ; Fritsche, Lars G ; Griffiths, Christopher J ; Hunt, Karen A ; Jansonius, Nomdo M ; Lopez-Pineda, Arturo ; Matsuda, Yuta ; Moatamed, Babak ; Nava-Aguilar, Marco A ; Numakura, Kensuke ; Patil, Snehal ; Richmond, Anne ; Rojas-Munoz, Agustin ; Shortt, Jonathan A ; Tao, Ran ; Vanderwerff, Brett ; Vernekar, Manvi ; Barnes, Kathleen C ; Boezen, Marike ; Chen, Zhengming ; Cho, Judy ; Smith, George Davey ; Finucane, Hilary K ; Franke, Lude ; Gamazon, Eric R ; Ganna, Andrea ; Gaunt, Tom R ; Ge, Tian ; Huang, Hailiang ; Huffman, Jennifer ; Koskela, Jukka T ; Lajonchere, Clara ; Law, Matthew H ; Li, Liming ; MacGregor, Stuart ; Olsen, Catherine M ; Trembath, Richard C ; Whiteman, David C ; Wicks, Stephen J ; Wijmenga, Cisca ; Zheng, Jie ; Zhou, Xiang ; Awadalla, Philip ; Boehnke, Michael ; Bustamante, Carlos D ; Cox, Nancy J ; Fatumo, Segun ; Geschwind, Daniel H ; Hayward, Caroline ; Kenny, Eimear E ; Lee, Seunggeun ; Lin, Yen-Feng ; Mbarek, Hamdi ; Magi, Reedik ; Martin, Hilary C ; Okada, Yukinori ; Pasaniuc, Bogdan ; Rader, Daniel J ; Ritchie, Marylyn D ; Sanna, Serena ; Walters, Robin G ; Zollner, Sebastian ; Willer, Cristen J ; Daly, Mark J

Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands 2022

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9
Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
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Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects

Howe, Laurence J ; Nivard, Michel G ; Morris, Tim T ; Hansen, Ailin F ; Rasheed, Humaira ; Cho, Yoonsu ; Chittoor, Geetha ; Ahlskog, Rafael ; Lind, Penelope A ; Palviainen, Teemu ; van der Zee, Matthijs D ; Cheesman, Rosa ; Mangino, Massimo ; Wang, Yunzhang ; Li, Shuai ; Klaric, Lucija ; Ratliff, Scott M ; Bielak, Lawrence F ; Nygaard, Marianne ; Giannelis, Alexandros ; Willoughby, Emily A ; Reynolds, Chandra A ; Balbona, Jared V ; Andreassen, Ole A ; Ask, Helga ; Baras, Aris ; Bauer, Christopher R ; Boomsma, Dorret I ; Campbell, Archie ; Campbell, Harry ; Chen, Zhengming ; Christofidou, Paraskevi ; Corfield, Elizabeth ; Dahm, Christina C ; Dokuru, Deepika R ; Evans, Luke M ; de Geus, Eco J. C ; Giddaluru, Sudheer ; Gordon, Scott D ; Harden, K. Paige ; Hill, W. David ; Hughes, Amanda ; Kerr, Shona M ; Kim, Yongkang ; Kweon, Hyeokmoon ; Latvala, Antti ; Lawlor, Deborah A ; Li, Liming ; Lin, Kuang ; Magnus, Per ; Magnusson, Patrik K. E ; Mallard, Travis T ; Martikainen, Pekka ; Mills, Melinda C ; Njolstad, Pal Rasmus ; Overton, John D ; Pedersen, Nancy L ; Porteous, David J ; Reid, Jeffrey ; Silventoinen, Karri ; Southey, Melissa C ; Stoltenberg, Camilla ; Tucker-Drob, Elliot M ; Wright, Margaret J ; Hewitt, John K ; Keller, Matthew C ; Stallings, Michael C ; Lee, James J ; Christensen, Kaare ; Kardia, Sharon L. R ; Peyser, Patricia A ; Smith, Jennifer A ; Wilson, James F ; Hopper, John L ; Hagg, Sara ; Spector, Tim D ; Pingault, Jean-Baptiste ; Plomin, Robert ; Havdahl, Alexandra ; Bartels, Meike ; Martin, Nicholas G ; Oskarsson, Sven ; Justice, Anne E ; Millwood, Iona Y ; Hveem, Kristian ; Naess, Oyvind ; Willer, Cristen J ; Asvold, Bjorn Olav ; Koellinger, Philipp D ; Kaprio, Jaakko ; Medland, Sarah E ; Walters, Robin G ; Benjamin, Daniel J ; Turley, Patrick ; Evans, David M ; Smith, George Davey ; Hayward, Caroline ; Brumpton, Ben ; Hemani, Gibran ; Davies, Neil M

Univ Edinburgh, Western Gen Hosp, Inst Genet & Canc, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland 2022

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10
Genetic insights into resting heart rate and its role in cardiovascular disease
Genetic insights into resting heart rate and its role in cardiovascular disease
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Genetic insights into resting heart rate and its role in cardiovascular disease

Eppinga, Ruben P ; Salfati, Elias Y ; Appel, Emil A ; Brody, Jennifer ; Polasek, Ozren ; Sveinbjornsson, Gardar ; Lecoeur, Cecile ; Ladenvall, Claes ; Isaacs, Aaron ; Luan, Jian'an ; Auro, Kirsi F ; Jackson, Anne ; Nethander, Maria ; Rankinen, Tuomo ; Zhao, Wei ; Robino, Antonietta ; Cocca, Massimiliano ; Lange, Leslie ; Mueller-Nurasyid, Martina ; Roselli, Carolina E ; Zhang, Weihua ; Guo, Xiuqing ; Lin, Henry E ; Galesloot, Tessel ; Noordam, Raymond E ; Milaneschi, Yuri ; Schraut, Katharina ; Degenhardt, Frauke E ; Trompet, Stella ; Pistis, Giorgio ; van der Most, Peter ; Lyytikaeinen, Leo-Pekka R ; Said, M. Abdullah ; Witte, Daniel ; Iribarren, Carlos M ; Launer, Lenore S ; Ring, Susan ; de Vries, Paul ; Sever, Peter P ; Sotoodehnia, Nona ; Kolcic, Ivana ; Roshandel, Delnaz D ; Paterson, Andrew O ; Salo, Perttu L ; Mohlke, Karen A ; Peyser, Patricia ; Schunkert, Heribert ; Lorentzon, Mattias ; Lahti, Jari C ; Rao, Dabeeru C ; Faul, Jessica A ; Stolarz-Skrzypek, Katarzyna ; Concas, Maria Pina ; Sinagra, Gianfranco ; Meitinger, Thomas ; Sinner, Moritz ; Strauch, Konstantin E ; Delgado, Graciela D ; Taylor, Kent ; Melander, Olle ; de Geus, Eco J. C ; Lind, Lars ; Franke, Andre W ; Tan, Nicholas B ; Felix, Stephan ; Tai, E-Shyong Q ; Snieder, Harold ; Ingelsson, Martin ; Raitakari, Olli ; Assimes, Themistocles ; Gudnason, Vilmundur J ; Timpson, Nicholas C ; Loos, Ruth J. F. R ; Vollenweider, Peter ; Groop, Leif J ; Wareham, Nicholas M ; Perola, Markus ; Kardia, Sharon L. R ; Erdmann, Jeanette ; Palmer, Colin N. A ; Eriksson, Johan ; Moebus, Susanne ; Weir, David ; Cusi, Daniele ; Girotto, Giorgia ; Correa, Adolfo ; Rotter, Jerome A ; Hicks, Andrew ; Smith, J. Gustav ; Penninx, Brenda W. J. H ; Wilson, James ; Sundström, Johan ; Lieb, Wolfgang ; Jukema, J. Wouter ; Eijgelsheim, Mark ; Lakatta, Edward L. M ; Cheng, Ching-Yu ; Doerr, Marcus ; Wong, Tien-Yin ; Verweij, Niek

Univ Edinburgh, Inst Genet & Mol Med, Ctr Genom & Expt Med, Edinburgh EH4 2XU, Midlothian, Scotland 2023

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