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Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer
Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer
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Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

Bradbury, Robert H. ; Acton, David G. ; Broadbent, Nicola L. ; Brooks, A. Nigel ; Carr, Gregory R. ; Hatter, Glenn ; Hayter, Barry R. ; Hill, Kathryn J. ; Howe, Nicholas J. ; Jones, Rhys D.O. ; Jude, David ; Lamont, Scott G. ; Loddick, Sarah A. ; McFarland, Heather L. ; Parveen, Zaieda ; Rabow, Alfred A. ; Sharma-Singh, Gorkhn ; Stratton, Natalie C. ; Thomason, Andrew G. ; Trueman, Dawn ; Walker, Graeme E. ; Wells, Stuart L. ; Wilson, Joanne ; Wood, J. Matthew

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.1945-1948 [Periódico revisado por pares]

England: Elsevier Ltd

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Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization
Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization
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Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization

Davies, Nicholas G.M. ; Browne, Helen ; Davis, Ben ; Drysdale, Martin J. ; Foloppe, Nicolas ; Geoffrey, Stephanie ; Gibbons, Ben ; Hart, Terance ; Hubbard, Roderick ; Jensen, Michael Rugaard ; Mansell, Howard ; Massey, Andrew ; Matassova, Natalia ; Moore, Jonathan D. ; Murray, James ; Pratt, Robert ; Ray, Stuart ; Robertson, Alan ; Roughley, Stephen D. ; Schoepfer, Joseph ; Scriven, Kirsten ; Simmonite, Heather ; Stokes, Stephen ; Surgenor, Allan ; Webb, Paul ; Wood, Mike ; Wright, Lisa ; Brough, Paul

Bioorganic & medicinal chemistry, 2012-11, Vol.20 (22), p.6770-6789 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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