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Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers
Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers
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Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers

HATA, Aaron N ; YEO, Alan ; MINO-KENUDSON, Mari ; WONG, Kwok-Kin ; ENGELMAN, Jeffrey A ; FABER, Anthony C ; LIFSHITS, Eugene ; ZHAO CHEN ; CHENG, Katherine A ; WALTON, Zandra ; SAROSIEK, Kristopher A ; LETAI, Anthony ; HEIST, Rebecca S

Cancer research (Chicago, Ill.), 2014-06, Vol.74 (11), p.3146-3156 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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2
Investigating New Mechanisms of Acquired Resistance to Targeted Therapies: If You Hit Them Harder, Do They Get Up Differently?
Investigating New Mechanisms of Acquired Resistance to Targeted Therapies: If You Hit Them Harder, Do They Get Up Differently?
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Investigating New Mechanisms of Acquired Resistance to Targeted Therapies: If You Hit Them Harder, Do They Get Up Differently?

Floros, Konstantinos V ; Hata, Aaron N ; Faber, Anthony C

Cancer research (Chicago, Ill.), 2020-01, Vol.80 (1), p.25-26 [Periódico revisado por pares]

United States

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3
Patient-Specific Tumor Growth Trajectories Determine Persistent and Resistant Cancer Cell Populations during Treatment with Targeted Therapies
Patient-Specific Tumor Growth Trajectories Determine Persistent and Resistant Cancer Cell Populations during Treatment with Targeted Therapies
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Patient-Specific Tumor Growth Trajectories Determine Persistent and Resistant Cancer Cell Populations during Treatment with Targeted Therapies

Grassberger, Clemens ; McClatchy, 3rd, David ; Geng, Changran ; Kamran, Sophia C ; Fintelmann, Florian ; Maruvka, Yosef E ; Piotrowska, Zofia ; Willers, Henning ; Sequist, Lecia V ; Hata, Aaron N ; Paganetti, Harald

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (14), p.3776-3788 [Periódico revisado por pares]

United States

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4
BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
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BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

Gupta, Manav ; Concepcion, Carla P ; Fahey, Caroline G ; Keshishian, Hasmik ; Bhutkar, Arjun ; Brainson, Christine F ; Sanchez-Rivera, Francisco J ; Pessina, Patrizia ; Kim, Jonathan Y ; Simoneau, Antoine ; Paschini, Margherita ; Beytagh, Mary C ; Stanclift, Caroline R ; Schenone, Monica ; Mani, D R ; Li, Chendi ; Oh, Audris ; Li, Fei ; Hu, Hai ; Karatza, Angeliki ; Bronson, Roderick T ; Shaw, Alice T ; Hata, Aaron N ; Wong, Kwok-Kin ; Zou, Lee ; Carr, Steven A ; Jacks, Tyler ; Kim, Carla F

Cancer research (Chicago, Ill.), 2020-09, Vol.80 (18), p.3841-3854 [Periódico revisado por pares]

United States

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5
Abstract 613: Development of FPA154, a novel tetravalent anti-GITR antibody, for the treatment of solid tumors
Abstract 613: Development of FPA154, a novel tetravalent anti-GITR antibody, for the treatment of solid tumors
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Abstract 613: Development of FPA154, a novel tetravalent anti-GITR antibody, for the treatment of solid tumors

Barbee, Susannah D. ; Chen, Amanda ; Johnson, Susan ; Bellovin, David I. ; Timmer, John C. ; Wondyfraw, Nebiyu ; Mkrtichyan, Mikayel ; Razai, Amir S. ; Jones, Kyle S. ; Hata, Chelsie Y. ; Gonzalez, Denise ; Deveraux, Quinn ; Eckelman, Brendan P. ; Borges, Luis

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.613-613 [Periódico revisado por pares]

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6
Abstract 2845: Co-acquisition of T790M and EMT in resistant EGFR mutant non-small cell lung cancer can be overcome by combined irreversible EGFR and BCL-XL inhibition
Abstract 2845: Co-acquisition of T790M and EMT in resistant EGFR mutant non-small cell lung cancer can be overcome by combined irreversible EGFR and BCL-XL inhibition
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Abstract 2845: Co-acquisition of T790M and EMT in resistant EGFR mutant non-small cell lung cancer can be overcome by combined irreversible EGFR and BCL-XL inhibition

Hata, Aaron N. ; Niederst, Matthew J. ; Archibald, Hannah L. ; Mulvey, Hillary ; Ham, Jungoh ; Gomez-Caraballo, Maria ; Kalsy, Anuj ; Faber, Anthony C. ; Engelman, Jeffrey

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2845-2845 [Periódico revisado por pares]

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7
A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis
A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis
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A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis

YAMAMOTO, Masaaki ; TORIGOE, Toshihiko ; OHMURA, Tousei ; YAMAGUCHI, Koji ; KUROTAKI, Takehiro ; HIRATA, Koichi ; SATO, Noriyuki ; KAMIGUCHI, Kenjiro ; HIROHASHI, Yoshihiko ; NAKANISHI, Katsuya ; NABETA, Chika ; ASANUMA, Hiroko ; TSURUMA, Tetsuhiro ; SATO, Takashi ; HATA, Fumitake

Cancer research (Chicago, Ill.), 2005-10, Vol.65 (19), p.8706-8714 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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8
Abstract 4568: Rapid assessment of TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF mutant melanoma
Abstract 4568: Rapid assessment of TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF mutant melanoma
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Abstract 4568: Rapid assessment of TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF mutant melanoma

Corcoran, Ryan B. ; Rothenberg, Stephen M. ; Hata, Aaron N. ; Faber, Anthony C. ; Winokur, Daniel ; Piris, Adriano ; Nazarian, Rosalynn M. ; Brown, Ronald D. ; Godfrey, Jason T. ; Mino-Kenudson, Mari ; Settleman, Jeffrey ; Wargo, Jennifer A. ; Flaherty, Keith T. ; Haber, Daniel A. ; Engelman, Jeffrey A.

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.4568-4568 [Periódico revisado por pares]

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9
Correlation of chromosome abnormalities with histological and clinical features in Wilm's and other childhood renal tumors
Correlation of chromosome abnormalities with histological and clinical features in Wilm's and other childhood renal tumors
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Correlation of chromosome abnormalities with histological and clinical features in Wilm's and other childhood renal tumors

KANEKO, Y ; HOMMA, C ; MASEKI, N ; SAKURAI, M ; HATA, J.-I

Cancer research (Chicago, Ill.), 1991-11, Vol.51 (21), p.5937-5942 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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10
Effects of steroid hormones and antisteroids on alkaline phosphatase activity in human endometrial cancer cells (Ishikawa line)
Effects of steroid hormones and antisteroids on alkaline phosphatase activity in human endometrial cancer cells (Ishikawa line)
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Effects of steroid hormones and antisteroids on alkaline phosphatase activity in human endometrial cancer cells (Ishikawa line)

HOLINKA, C. F ; HATA, H ; KURAMOTO, H ; GURPIDE, E

Cancer research (Chicago, Ill.), 1986-06, Vol.46 (6), p.2771-2774 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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