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Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1‑f][triazin-4-amino] Adenine C‑Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1‑f][triazin-4-amino] Adenine C‑Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses
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Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1‑f][triazin-4-amino] Adenine C‑Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

Siegel, Dustin ; Hui, Hon C ; Doerffler, Edward ; Clarke, Michael O ; Chun, Kwon ; Zhang, Lijun ; Neville, Sean ; Carra, Ernest ; Lew, Willard ; Ross, Bruce ; Wang, Queenie ; Wolfe, Lydia ; Jordan, Robert ; Soloveva, Veronica ; Knox, John ; Perry, Jason ; Perron, Michel ; Stray, Kirsten M ; Barauskas, Ona ; Feng, Joy Y ; Xu, Yili ; Lee, Gary ; Rheingold, Arnold L ; Ray, Adrian S ; Bannister, Roy ; Strickley, Robert ; Swaminathan, Swami ; Lee, William A ; Bavari, Sina ; Cihlar, Tomas ; Lo, Michael K ; Warren, Travis K ; Mackman, Richard L

Journal of medicinal chemistry, 2017-03, Vol.60 (5), p.1648-1661 [Periódico revisado por pares]

United States: American Chemical Society

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2
BCX4430 – A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease
BCX4430 – A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease
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BCX4430 – A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease

Taylor, Raymond ; Kotian, Pravin ; Warren, Travis ; Panchal, Rekha ; Bavari, Sina ; Julander, Justin ; Dobo, Sylvia ; Rose, Angela ; El-Kattan, Yahya ; Taubenheim, Brian ; Babu, Yarlagadda ; Sheridan, William P

Journal of infection and public health, 2016-05, Vol.9 (3), p.220-226 [Periódico revisado por pares]

England: Elsevier Ltd

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3
The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines
The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines
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The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines

Luban, Jeremy ; Sattler, Rachel A. ; Mühlberger, Elke ; Graci, Jason D. ; Cao, Liangxian ; Weetall, Marla ; Trotta, Christopher ; Colacino, Joseph M. ; Bavari, Sina ; Strambio-De-Castillia, Caterina ; Suder, Ellen L. ; Wang, Yetao ; Soloveva, Veronica ; Cintron-Lue, Katherine ; Naryshkin, Nikolai A. ; Pykett, Mark ; Welch, Ellen M. ; O’Keefe, Kylie ; Kong, Ronald ; Goodwin, Elizabeth ; Jacobson, Allan ; Paessler, Slobodan ; Peltz, Stuart W.

Virus research, 2021-01, Vol.292, p.198246-198246, Article 198246 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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4
ICTV Virus Taxonomy Profile: Filoviridae
ICTV Virus Taxonomy Profile: Filoviridae
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ICTV Virus Taxonomy Profile: Filoviridae

Kuhn, Jens H ; Amarasinghe, Gaya K ; Basler, Christopher F ; Bavari, Sina ; Bukreyev, Alexander ; Chandran, Kartik ; Crozier, Ian ; Dolnik, Olga ; Dye, John M ; Formenty, Pierre B H ; Griffiths, Anthony ; Hewson, Roger ; Kobinger, Gary P ; Leroy, Eric M ; Mühlberger, Elke ; Netesov Нетёсов Сергей Викторович, Sergey V ; Palacios, Gustavo ; Pályi, Bernadett ; Pawęska, Janusz T ; Smither, Sophie J ; Takada 高田礼人, Ayato ; Towner, Jonathan S ; Wahl, Victoria ; Ictv Report Consortium

Journal of general virology, 2019-06, Vol.100 (6), p.911-912 [Periódico revisado por pares]

England: Microbiology Society

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5
Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus
Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus
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Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus

Huang, I-Chueh ; Bailey, Charles C ; Weyer, Jessica L ; Radoshitzky, Sheli R ; Becker, Michelle M ; Chiang, Jessica J ; Brass, Abraham L ; Ahmed, Asim A ; Chi, Xiaoli ; Dong, Lian ; Longobardi, Lindsay E ; Boltz, Dutch ; Kuhn, Jens H ; Elledge, Stephen J ; Bavari, Sina ; Denison, Mark R ; Choe, Hyeryun ; Farzan, Michael Baric, Ralph S.

PLoS pathogens, 2011-01, Vol.7 (1), p.e1001258-e1001258 [Periódico revisado por pares]

United States: Public Library of Science

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6
A systematic screen of FDA-approved drugs for inhibitors of biological threat agents
A systematic screen of FDA-approved drugs for inhibitors of biological threat agents
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A systematic screen of FDA-approved drugs for inhibitors of biological threat agents

Madrid, Peter B ; Chopra, Sidharth ; Manger, Ian D ; Gilfillan, Lynne ; Keepers, Tiffany R ; Shurtleff, Amy C ; Green, Carol E ; Iyer, Lalitha V ; Dilks, Holli Hutcheson ; Davey, Robert A ; Kolokoltsov, Andrey A ; Carrion, Jr, Ricardo ; Patterson, Jean L ; Bavari, Sina ; Panchal, Rekha G ; Warren, Travis K ; Wells, Jay B ; Moos, Walter H ; Burke, Raelyn L ; Tanga, Mary J Yu, Xue-jie

PloS one, 2013-04, Vol.8 (4), p.e60579-e60579 [Periódico revisado por pares]

United States: Public Library of Science

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7
Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon
Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon
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Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon

Smith, Darci R ; Hollidge, Bradley ; Daye, Sharon ; Zeng, Xiankun ; Blancett, Candace ; Kuszpit, Kyle ; Bocan, Thomas ; Koehler, Jeff W ; Coyne, Susan ; Minogue, Tim ; Kenny, Tara ; Chi, Xiaoli ; Yim, Soojin ; Miller, Lynn ; Schmaljohn, Connie ; Bavari, Sina ; Golden, Joseph W Harris, Eva

PLoS neglected tropical diseases, 2017-01, Vol.11 (1), p.e0005296-e0005296 [Periódico revisado por pares]

United States: Public Library of Science

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8
Sorafenib Impedes Rift Valley Fever Virus Egress by Inhibiting Valosin-Containing Protein Function in the Cellular Secretory Pathway
Sorafenib Impedes Rift Valley Fever Virus Egress by Inhibiting Valosin-Containing Protein Function in the Cellular Secretory Pathway
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Sorafenib Impedes Rift Valley Fever Virus Egress by Inhibiting Valosin-Containing Protein Function in the Cellular Secretory Pathway

Brahms, Ashwini ; Mudhasani, Rajini ; Pinkham, Chelsea ; Kota, Krishna ; Nasar, Farooq ; Zamani, Rouzbeh ; Bavari, Sina ; Kehn-Hall, Kylene Schultz-Cherry, Stacey

Journal of virology, 2017-11, Vol.91 (21) [Periódico revisado por pares]

United States: American Society for Microbiology

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9
Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication
Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication
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Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication

Tsai, Yien Che ; Kotiya, Archana ; Kiris, Erkan ; Yang, Mei ; Bavari, Sina ; Tessarollo, Lino ; Oyler, George A. ; Weissman, Allan M.

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (26), p.E5158-E5166 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus
The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus
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The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus

Jasenosky, Luke D. ; Cadena, Cristhian ; Mire, Chad E. ; Borisevich, Viktoriya ; Haridas, Viraga ; Ranjbar, Shahin ; Nambu, Aya ; Bavari, Sina ; Soloveva, Veronica ; Sadukhan, Supriya ; Cassell, Gail H. ; Geisbert, Thomas W. ; Hur, Sun ; Goldfeld, Anne E.

iScience, 2019-09, Vol.19, p.1279-1290 [Periódico revisado por pares]

United States: Elsevier Inc

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