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1
Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases
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Artigo
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Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases

Ota, Mineto ; Nagafuchi, Yasuo ; Hatano, Hiroaki ; Ishigaki, Kazuyoshi ; Terao, Chikashi ; Takeshima, Yusuke ; Yanaoka, Haruyuki ; Kobayashi, Satomi ; Okubo, Mai ; Shirai, Harumi ; Sugimori, Yusuke ; Maeda, Junko ; Nakano, Masahiro ; Yamada, Saeko ; Yoshida, Ryochi ; Tsuchiya, Haruka ; Tsuchida, Yumi ; Akizuki, Shuji ; Yoshifuji, Hajime ; Ohmura, Koichiro ; Mimori, Tsuneyo ; Yoshida, Ken ; Kurosaka, Daitaro ; Okada, Masato ; Setoguchi, Keigo ; Kaneko, Hiroshi ; Ban, Nobuhiro ; Yabuki, Nami ; Matsuki, Kosuke ; Mutoh, Hironori ; Oyama, Sohei ; Okazaki, Makoto ; Tsunoda, Hiroyuki ; Iwasaki, Yukiko ; Sumitomo, Shuji ; Shoda, Hirofumi ; Kochi, Yuta ; Okada, Yukinori ; Yamamoto, Kazuhiko ; Okamura, Tomohisa ; Fujio, Keishi

Cell, 2021-05, Vol.184 (11), p.3006-3021.e17 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
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Artigo
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Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes

Cristescu, Razvan ; Lee, Jeeyun ; Nebozhyn, Michael ; Kim, Kyoung-Mee ; Ting, Jason C ; Wong, Swee Seong ; Liu, Jiangang ; Yue, Yong Gang ; Wang, Jian ; Yu, Kun ; Ye, Xiang S ; Do, In-Gu ; Liu, Shawn ; Gong, Lara ; Fu, Jake ; Jin, Jason Gang ; Choi, Min Gew ; Sohn, Tae Sung ; Lee, Joon Ho ; Bae, Jae Moon ; Kim, Seung Tae ; Park, Se Hoon ; Sohn, Insuk ; Jung, Sin-Ho ; Tan, Patrick ; Chen, Ronghua ; Hardwick, James ; Kang, Won Ki ; Ayers, Mark ; Hongyue, Dai ; Reinhard, Christoph ; Loboda, Andrey ; Kim, Sung ; Aggarwal, Amit

Nature medicine, 2015-05, Vol.21 (5), p.449-456 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
Integrated analysis of co‐expression and ceRNA network identifies five lncRNAs as prognostic markers for breast cancer
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Artigo
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Integrated analysis of co‐expression and ceRNA network identifies five lncRNAs as prognostic markers for breast cancer

Yao, Yan ; Zhang, Tingting ; Qi, Lingyu ; Zhou, Chao ; Wei, Junyu ; Feng, Fubin ; Liu, Ruijuan ; Sun, Changgang

Journal of cellular and molecular medicine, 2019-12, Vol.23 (12), p.8410-8419 [Periódico revisado por pares]

England: John Wiley & Sons, Inc

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4
Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma
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Artigo
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Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma

McDermott, David F ; Huseni, Mahrukh A ; Atkins, Michael B ; Motzer, Robert J ; Rini, Brian I ; Escudier, Bernard ; Fong, Lawrence ; Joseph, Richard W ; Pal, Sumanta K ; Reeves, James A ; Sznol, Mario ; Hainsworth, John ; Rathmell, W Kimryn ; Stadler, Walter M ; Hutson, Thomas ; Gore, Martin E ; Ravaud, Alain ; Bracarda, Sergio ; Suárez, Cristina ; Danielli, Riccardo ; Gruenwald, Viktor ; Choueiri, Toni K ; Nickles, Dorothee ; Jhunjhunwala, Suchit ; Piault-Louis, Elisabeth ; Thobhani, Alpa ; Qiu, Jiaheng ; Chen, Daniel S ; Hegde, Priti S ; Schiff, Christina ; Fine, Gregg D ; Powles, Thomas

Nature medicine, 2018-06, Vol.24 (6), p.749-757 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
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Artigo
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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Gay, Carl M. ; Stewart, C. Allison ; Park, Elizabeth M. ; Diao, Lixia ; Groves, Sarah M. ; Heeke, Simon ; Nabet, Barzin Y. ; Fujimoto, Junya ; Solis, Luisa M. ; Lu, Wei ; Xi, Yuanxin ; Cardnell, Robert J. ; Wang, Qi ; Fabbri, Giulia ; Cargill, Kasey R. ; Vokes, Natalie I. ; Ramkumar, Kavya ; Zhang, Bingnan ; Della Corte, Carminia M. ; Robson, Paul ; Swisher, Stephen G. ; Roth, Jack A. ; Glisson, Bonnie S. ; Shames, David S. ; Wistuba, Ignacio I. ; Wang, Jing ; Quaranta, Vito ; Minna, John ; Heymach, John V. ; Byers, Lauren Averett

Cancer cell, 2021-03, Vol.39 (3), p.346-360.e7 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
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Artigo
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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

Herman, Sarah E.M. ; Gordon, Amber L. ; Hertlein, Erin ; Ramanunni, Asha ; Zhang, Xiaoli ; Jaglowski, Samantha ; Flynn, Joseph ; Jones, Jeffrey ; Blum, Kristie A. ; Buggy, Joseph J. ; Hamdy, Ahmed ; Johnson, Amy J. ; Byrd, John C.

Blood, 2011-06, Vol.117 (23), p.6287-6296 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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7
HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer
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Artigo
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HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer

Kim, K ; Jutooru, I ; Chadalapaka, G ; Johnson, G ; Frank, J ; Burghardt, R ; Kim, S ; Safe, S

Oncogene, 2013-03, Vol.32 (13), p.1616-1625 [Periódico revisado por pares]

England: Nature Publishing Group

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8
The Somatic Genomic Landscape of Glioblastoma
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Artigo
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The Somatic Genomic Landscape of Glioblastoma

Brennan, Cameron W. ; Noushmehr, Houtan ; Salama, Sofie R. ; Berman, Samuel H. ; Beroukhim, Rameen ; Wu, Chang-Jiun ; Yung, W.K. ; Sougnez, Carrie ; Finocchiaro, Gaetano ; O’Neill, Brian P. ; Myers, Jerome ; Weisenberger, Daniel J. ; Penny, Robert ; Marra, Marco ; Meyerson, Matthew ; Chin, Lynda ; Ostrom, Quinn ; Wolinsky, Yingli ; Black, Keith L. ; Boulos, Madgy ; Brown, Jenn ; Czerinski, Christine ; Koyfman, Yakov ; Rabeno, Brenda ; Auman, J.Todd ; Lee, Semin ; Kalkanis, Steven ; Mikkelsen, Tom ; Scarpace, Lisa ; Reynolds, Sheila ; Curley, Erin ; Morris, Scott ; Yena, Peggy ; Cuppini, Lucia ; Maderna, Emanuela ; Pollo, Bianca ; Hoadley, Katherine A. ; Shi, Yan ; Topal, Michael D. ; Aksoy, B. Arman ; Antipin, Yevgeniy ; Borsu, Laetitia ; Brennan, Cameron W. ; Gao, Jianjiong ; Jacobsen, Anders ; Ladanyi, Marc ; Lash, Alex ; Liang, Yupu ; Chen, Qing-Rong ; Shaw, Kenna R. Mills ; Eckman, John ; Eley, Greg ; Jensen, Mark A. ; Kahn, Ari ; Pot, David A. ; Wan, Yunhu ; Hansen, Nathan ; Hothi, Parvi ; Lau, Ching ; Cherniack, Andrew D. ; Noble, Mike ; Cibulskis, Kristian ; Frazer, Scott ; Gabriel, Stacey B. ; Gehlenborg, Nils ; Gentry, Jeff ; Heiman, David ; Lander, Eric S. ; Mallard, Will ; Meyerson, Matthew ; Getz, Gad ; Dees, Nathan N. ; Fulton, Robert S. ; Kanchi, Krishna-Latha ; Devine, Karen ; Carlin, Daniel ; Ellrott, Kyle ; Haussler, David ; Ng, Sam ; Salama, Sofie R. ; Waltman, Peter ; Zhu, Jing ; Frentzen, Barbara ; Friedman, William ; McTiernan, Raquel ; Perou, Charles M. ; Akbani, Rehan ; Aldape, Kenneth ; Bogler, Oliver ; Fuller, Gregory N. ; Mills, Gordon ; Protopopov, Alexei ; Wu, Chang-Jiun ; Weinstein, John N. ; Verhaak, Roel G.W. ; Noushmehr, Houtan ; Triche, Timothy J. ; Laird, Peter W. ; VanMeir, Erwin G. ; Brat, Daniel

Cell, 2013-10, Vol.155 (2), p.462-477 [Periódico revisado por pares]

United States: Elsevier Inc

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9
A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast
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Artigo
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A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast

Pal, Bhupinder ; Chen, Yunshun ; Vaillant, François ; Capaldo, Bianca D ; Joyce, Rachel ; Song, Xiaoyu ; Bryant, Vanessa L ; Penington, Jocelyn S ; Di Stefano, Leon ; Tubau Ribera, Nina ; Wilcox, Stephen ; Mann, Gregory B ; Papenfuss, Anthony T ; Lindeman, Geoffrey J ; Smyth, Gordon K ; Visvader, Jane E

The EMBO journal, 2021-06, Vol.40 (11), p.e107333-n/a [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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10
Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies
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Artigo
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Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies

Jiang, Yi-Zhou ; Ma, Ding ; Suo, Chen ; Shi, Jinxiu ; Xue, Mengzhu ; Hu, Xin ; Xiao, Yi ; Yu, Ke-Da ; Liu, Yi-Rong ; Yu, Ying ; Zheng, Yuanting ; Li, Xiangnan ; Zhang, Chenhui ; Hu, Pengchen ; Zhang, Jing ; Hua, Qi ; Zhang, Jiyang ; Hou, Wanwan ; Ren, Luyao ; Bao, Ding ; Li, Bingying ; Yang, Jingcheng ; Yao, Ling ; Zuo, Wen-Jia ; Zhao, Shen ; Gong, Yue ; Ren, Yi-Xing ; Zhao, Ya-Xin ; Yang, Yun-Song ; Niu, Zhenmin ; Cao, Zhi-Gang ; Stover, Daniel G. ; Verschraegen, Claire ; Kaklamani, Virginia ; Daemen, Anneleen ; Benson, John R. ; Takabe, Kazuaki ; Bai, Fan ; Li, Da-Qiang ; Wang, Peng ; Shi, Leming ; Huang, Wei ; Shao, Zhi-Ming

Cancer cell, 2019-03, Vol.35 (3), p.428-440.e5 [Periódico revisado por pares]

United States: Elsevier Inc

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