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Material Type: Artigo
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SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4Deysi Viviana T. Wong Helder Veras Ribeiro Filho; Carlos Wagner Souza Wanderley; Caio Abner Vitorino Gonçalves Leite; Jonilson Berlink Lima; Alexia Nathália Brígido Assef; Aurilene Gomes Cajado; Gabriela Loiola Ponte Batista; Rafael Holanda González; Karla Oliveira Silva; Luis Philipi Carvalho Borges; Nylane Maria Nunes de Alencar; Diego Veras Wilke; Thiago Mattar Cunha; Ana Carolina Migliorini Figueira; Fernando de Queiroz Cunha; Roberto César P Lima JúniorCancer Chemotherapy and Pharmacology Heidelberg v. 84, n. 2, p. 287-298, 2019Heidelberg 2019Localização: FMRP - Fac. Medicina de Ribeirão Preto (pcd 3011835 Acervo Digital )(Acessar) |
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Material Type: Artigo
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Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal DeliveryXing, R. ; Mustapha, O. ; Ali, T. ; Rehman, M. ; Zaidi, S. S. ; Baseer, A. ; Batool, S. ; Mukhtiar, M. ; Shafique, S. ; Malik, M. ; Sohail, S. ; Ali, Z. ; Zahid, F. ; Zeb, A. ; Shah, F. ; Yousaf, A. ; Din, F. Di Stefano, Luisa ; Luisa Di StefanoBioMed research international, 2021, Vol.2021, p.9968602-14 [Periódico revisado por pares]United States: HindawiTexto completo disponível |
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Material Type: Artigo
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Targeting Topoisomerase I in the Era of Precision MedicineThomas, Anish ; Pommier, YvesClinical cancer research, 2019-11, Vol.25 (22), p.6581-6589 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Bevacizumab Combined With Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer: The AURELIA Open-Label Randomized Phase III TrialPUJADE-LAURAINE, Eric ; HILPERT, Felix ; PEREIRA, Deolinda ; WIMBERGER, Pauline ; OAKNIN, Ana ; MIRZA, Mansoor Raza ; FOLLANA, Philippe ; BOLLAG, David ; RAY-COQUARD, Isabelle ; WEBER, Béatrice ; REUSS, Alexander ; POVEDA, Andres ; KRISTENSEN, Gunnar ; SORIO, Roberto ; VERGOTE, Ignace ; WITTEVEEN, Petronella ; BAMIAS, AristotelisJournal of clinical oncology, 2014-05, Vol.32 (13), p.1302-1308 [Periódico revisado por pares]Alexandria, VA: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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Development of topotecan loaded lipid nanoparticles for chemical stabilization and prolonged releaseSouza, L.G. ; Silva, E.J. ; Martins, A.L.L. ; Mota, M.F. ; Braga, R.C. ; Lima, E.M. ; Valadares, M.C. ; Taveira, S.F. ; Marreto, R.N.European journal of pharmaceutics and biopharmaceutics, 2011-09, Vol.79 (1), p.189-196 [Periódico revisado por pares]Netherlands: Elsevier B.VTexto completo disponível |
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Material Type: Artigo
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Image-guided thermosensitive liposomes for focused ultrasound drug delivery: Using NIRF-labelled lipids and topotecan to visualise the effects of hyperthermia in tumoursCentelles, Miguel N. ; Wright, Michael ; So, Po-Wah ; Amrahli, Maral ; Xu, Xiao Yun ; Stebbing, Justin ; Miller, Andrew D. ; Gedroyc, Wladyslaw ; Thanou, MayaJournal of controlled release, 2018-06, Vol.280, p.87-98 [Periódico revisado por pares]Netherlands: Elsevier B.VTexto completo disponível |
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Material Type: Artigo
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ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forksBalmus, Gabriel ; Pilger, Domenic ; Coates, Julia ; Demir, Mukerrem ; Sczaniecka-Clift, Matylda ; Barros, Ana C ; Woods, Michael ; Fu, Beiyuan ; Yang, Fengtang ; Chen, Elisabeth ; Ostermaier, Matthias ; Stankovic, Tatjana ; Ponstingl, Hannes ; Herzog, Mareike ; Yusa, Kosuke ; Martinez, Francisco Munoz ; Durant, Stephen T ; Galanty, Yaron ; Beli, Petra ; Adams, David J ; Bradley, Allan ; Metzakopian, Emmanouil ; Forment, Josep V ; Jackson, Stephen PNature communications, 2019-01, Vol.10 (1), p.87-18, Article 87 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Carboplatin plus etoposide versus topotecan as second-line treatment for patients with sensitive relapsed small-cell lung cancer: an open-label, multicentre, randomised, phase 3 trialBaize, Nathalie ; Monnet, Isabelle ; Greillier, Laurent ; Geier, Margaux ; Lena, Hervé ; Janicot, Henri ; Vergnenegre, Alain ; Crequit, Jacky ; Lamy, Regine ; Auliac, Jean-Bernard ; Letreut, Jacques ; Le Caer, Hervé ; Gervais, Radj ; Dansin, Eric ; Madroszyk, Anne ; Renault, Patrick-Aldo ; Le Garff, Gwenaëlle ; Falchero, Lionel ; Berard, Henri ; Schott, Roland ; Saulnier, Patrick ; Chouaid, ChristosThe lancet oncology, 2020-09, Vol.21 (9), p.1224-1233 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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A Phase I Clinical Trial of the Poly(ADP-ribose) Polymerase Inhibitor Veliparib and Weekly Topotecan in Patients with Solid TumorsWahner Hendrickson, Andrea E ; Menefee, Michael E ; Hartmann, Lynn C ; Long, Harry J ; Northfelt, Donald W ; Reid, Joel M ; Boakye-Agyeman, Felix ; Kayode, Olumide ; Flatten, Karen S ; Harrell, Maria I ; Swisher, Elizabeth M ; Poirier, Guy G ; Satele, Daniel ; Allred, Jake ; Lensing, Janet L ; Chen, Alice ; Ji, Jiuping ; Zang, Yiping ; Erlichman, Charles ; Haluska, Paul ; Kaufmann, Scott HClinical cancer research, 2018-02, Vol.24 (4), p.744-752 [Periódico revisado por pares]United States: American Association for Cancer Research IncTexto completo disponível |
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10 |
Material Type: Artigo
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Safety and tolerability of the poly(ADP-ribose) polymerase (PARP) inhibitor, olaparib (AZD2281) in combination with topotecan for the treatment of patients with advanced solid tumors: a phase I studySamol, Jens ; Ranson, Malcolm ; Scott, Edwina ; Macpherson, Euan ; Carmichael, James ; Thomas, Anne ; Cassidy, JamesInvestigational new drugs, 2012-08, Vol.30 (4), p.1493-1500 [Periódico revisado por pares]Boston: Springer USTexto completo disponível |