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Refinado por: Nome da Publicação: Journal Of Medicinal Chemistry remover assunto: Molecular Structure remover Life Sciences & Biomedicine remover
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What is in Our Kit? An Analysis of Building Blocks Used in Medicinal Chemistry Parallel Libraries
What is in Our Kit? An Analysis of Building Blocks Used in Medicinal Chemistry Parallel Libraries
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What is in Our Kit? An Analysis of Building Blocks Used in Medicinal Chemistry Parallel Libraries

Wang, Ying ; Haight, Isabella ; Gupta, Rishi ; Vasudevan, Anil

Journal of medicinal chemistry, 2021-12, Vol.64 (23), p.17115-17122 [Periódico revisado por pares]

United States: American Chemical Society

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2
Chemical Space of DNA-Encoded Libraries
Chemical Space of DNA-Encoded Libraries
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Chemical Space of DNA-Encoded Libraries

Franzini, Raphael M ; Randolph, Cassie

Journal of medicinal chemistry, 2016-07, Vol.59 (14), p.6629-6644 [Periódico revisado por pares]

United States

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3
Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?
Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?
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Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?

Newman, David J

Journal of medicinal chemistry, 2008-05, Vol.51 (9), p.2589-2599 [Periódico revisado por pares]

United States: American Chemical Society

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4
Discovery of Multitarget Inhibitors by Combining Molecular Docking with Common Pharmacophore Matching
Discovery of Multitarget Inhibitors by Combining Molecular Docking with Common Pharmacophore Matching
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Discovery of Multitarget Inhibitors by Combining Molecular Docking with Common Pharmacophore Matching

Wei, Dengguo ; Jiang, Xiaolu ; Zhou, Lu ; Chen, Jing ; Chen, Zheng ; He, Chong ; Yang, Kun ; Liu, Ying ; Pei, Jianfeng ; Lai, Luhua

Journal of medicinal chemistry, 2008-12, Vol.51 (24), p.7882-7888 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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5
Synthesis and Evaluation of Novel Inhibitors of Pim-1 and Pim-2 Protein Kinases
Synthesis and Evaluation of Novel Inhibitors of Pim-1 and Pim-2 Protein Kinases
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Synthesis and Evaluation of Novel Inhibitors of Pim-1 and Pim-2 Protein Kinases

Xia, Zuping ; Knaak, Christian ; Ma, Jian ; Beharry, Zanna M ; McInnes, Campbell ; Wang, Wenxue ; Kraft, Andrew S ; Smith, Charles D

Journal of medicinal chemistry, 2009-01, Vol.52 (1), p.74-86 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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6
Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
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Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells

Grasberger, Bruce L ; Lu, Tianbao ; Schubert, Carsten ; Parks, Daniel J ; Carver, Theodore E ; Koblish, Holly K ; Cummings, Maxwell D ; LaFrance, Louis V ; Milkiewicz, Karen L ; Calvo, Raul R ; Maguire, Diane ; Lattanze, Jennifer ; Franks, Carol F ; Zhao, Shuyuan ; Ramachandren, Kannan ; Bylebyl, Gwendolyn R ; Zhang, Marie ; Manthey, Carl L ; Petrella, Eugene C ; Pantoliano, Michael W ; Deckman, Ingrid C ; Spurlino, John C ; Maroney, Anna C ; Tomczuk, Bruce E ; Molloy, Christopher J ; Bone, Roger F

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.909-912 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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7
Do Structurally Similar Molecules Have Similar Biological Activity?
Do Structurally Similar Molecules Have Similar Biological Activity?
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Do Structurally Similar Molecules Have Similar Biological Activity?

Martin, Yvonne C ; Kofron, James L ; Traphagen, Linda M

Journal of medicinal chemistry, 2002-09, Vol.45 (19), p.4350-4358 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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8
Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization
Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization
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Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization

Whiting, Matthew ; Tripp, Jonathan C ; Lin, Ying-Chuan ; Lindstrom, William ; Olson, Arthur J ; Elder, John H ; Sharpless, K. Barry ; Fokin, Valery V

Journal of medicinal chemistry, 2006-12, Vol.49 (26), p.7697-7710 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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9
Discovery of Potent Inhibitors of Soluble Epoxide Hydrolase by Combinatorial Library Design and Structure-Based Virtual Screening
Discovery of Potent Inhibitors of Soluble Epoxide Hydrolase by Combinatorial Library Design and Structure-Based Virtual Screening
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Discovery of Potent Inhibitors of Soluble Epoxide Hydrolase by Combinatorial Library Design and Structure-Based Virtual Screening

Xing, Li ; McDonald, Joseph J ; Kolodziej, Steve A ; Kurumbail, Ravi G ; Williams, Jennifer M ; Warren, Chad J ; O’Neal, Janet M ; Skepner, Jill E ; Roberds, Steven L

Journal of medicinal chemistry, 2011-03, Vol.54 (5), p.1211-1222 [Periódico revisado por pares]

United States: American Chemical Society

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10
Blocking Estrogen Signaling After the Hormone: Pyrimidine-Core Inhibitors of Estrogen Receptor-Coactivator Binding
Blocking Estrogen Signaling After the Hormone: Pyrimidine-Core Inhibitors of Estrogen Receptor-Coactivator Binding
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Blocking Estrogen Signaling After the Hormone: Pyrimidine-Core Inhibitors of Estrogen Receptor-Coactivator Binding

Parent, Alexander A ; Gunther, Jillian R ; Katzenellenbogen, John A

Journal of medicinal chemistry, 2008-10, Vol.51 (20), p.6512-6530 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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