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Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent
Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent
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Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent

Merchant, Mark ; Ma, Xiaolei ; Maun, Henry R ; Zheng, Zhong ; Peng, Jing ; Romero, Mally ; Huang, Arthur ; Yang, Nai-ying ; Nishimura, Merry ; Greve, Joan ; Santell, Lydia ; Zhang, Yu-Wen ; Su, Yanli ; Kaufman, Dafna W ; Billeci, Karen L ; Mai, Elaine ; Moffat, Barbara ; Lim, Amy ; Duenas, Eileen T ; Phillips, Heidi S ; Xiang, Hong ; Young, Judy C ; Vande Woude, George F ; Dennis, Mark S ; Reilly, Dorothea E ; Schwall, Ralph H ; Starovasnik, Melissa A ; Lazarus, Robert A ; Yansura, Daniel G

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (32), p.E2987-E2996 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal–fetal interface
Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal–fetal interface
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Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal–fetal interface

Fu, Binqing ; Li, Xianchang ; Sun, Rui ; Tong, Xianhong ; Ling, Bin ; Tian, Zhigang ; Wei, Haiming

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (3), p.E231-E240 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
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Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells

Tekguc, Murat ; Wing, James Badger ; Osaki, Motonao ; Long, Jia ; Sakaguchi, Shimon

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (30) [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Mechanistic basis of infertility of mouse intersubspecific hybrids
Mechanistic basis of infertility of mouse intersubspecific hybrids
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Mechanistic basis of infertility of mouse intersubspecific hybrids

Bhattacharyya, Tanmoy ; Gregorova, Sona ; Mihola, Ondrej ; Anger, Martin ; Sebestova, Jaroslava ; Denny, Paul ; Simecek, Petr ; Forejt, Jiri

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (6), p.E468-E477 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes
Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes
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Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Kowanetz, Marcin ; Wu, Xiumin ; Lee, John ; Tan, Martha ; Hagenbeek, Thijs ; Qu, Xueping ; Yu, Lanlan ; Ross, Jed ; Korsisaari, Nina ; Cao, Tim ; Bou-Reslan, Hani ; Kallop, Dara ; Weimer, Robby ; Ludlam, Mary J. C. ; Kaminker, Joshua S. ; Modrusan, Zora ; van Bruggen, Nicholas ; Peale, Franklin V. ; Carano, Richard ; Meng, Y. Gloria ; Ferrara, Napoleone

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21248-21255 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis
Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis
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Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis

Raverdeau, Mathilde ; Gely-Pernot, Aurore ; Féret, Betty ; Dennefeld, Christine ; Benoit, Gérard ; Davidson, Irwin ; Chambon, Pierre ; Mark, Manuel ; Ghyselinck, Norbert B

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.16582-16587 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
Two physically, functionally, and developmentally distinct peritoneal macrophage subsets
Two physically, functionally, and developmentally distinct peritoneal macrophage subsets
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Two physically, functionally, and developmentally distinct peritoneal macrophage subsets

Ghosn, Eliver Eid Bou ; Cassado, Alexandra A ; Govoni, Gregory R ; Fukuhara, Takeshi ; Yang, Yang ; Monack, Denise M ; Bortoluci, Karina R ; Almeida, Sandro R ; Herzenberg, Leonard A ; Herzenberg, Leonore A

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2568-2573 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Eosinophils secrete IL-4 to facilitate liver regeneration
Eosinophils secrete IL-4 to facilitate liver regeneration
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Eosinophils secrete IL-4 to facilitate liver regeneration

Goh, Y. P. Sharon ; Henderson, Neil C. ; Heredia, Jose E. ; Eagle, Alex Red ; Odegaard, Justin I. ; Lehwald, Nadja ; Nguyen, Khoa D. ; Sheppard, Dean ; Mukundan, Lata ; Locksley, Richard M. ; Chawla, Ajay

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9914-9919 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Immune-mediated antitumor effect by type 2 diabetes drug, metformin
Immune-mediated antitumor effect by type 2 diabetes drug, metformin
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Immune-mediated antitumor effect by type 2 diabetes drug, metformin

Eikawa, Shingo ; Nishida, Mikako ; Mizukami, Shusaku ; Yamazaki, Chihiro ; Nakayama, Eiichi ; Udono, Heiichiro

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (6), p.1809-1814 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells
Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells
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Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

Jinushi, Masahisa ; Chiba, Shigeki ; Yoshiyama, Hironori ; Masutomi, Kenkichi ; Kinoshita, Ichiro ; Dosaka-Akita, Hirotoshi ; Yagita, Hideo ; Takaoka, Akinori ; Tahara, Hideaki

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (30), p.12425-12430 [Periódico revisado por pares]

United States: National Academy of Sciences

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