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Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor
Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor
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Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

Perera, Timothy P S ; Jovcheva, Eleonora ; Mevellec, Laurence ; Vialard, Jorge ; De Lange, Desiree ; Verhulst, Tinne ; Paulussen, Caroline ; Van De Ven, Kelly ; King, Peter ; Freyne, Eddy ; Rees, David C ; Squires, Matthew ; Saxty, Gordon ; Page, Martin ; Murray, Christopher W ; Gilissen, Ron ; Ward, George ; Thompson, Neil T ; Newell, David R ; Cheng, Na ; Xie, Liang ; Yang, Jennifer ; Platero, Suso J ; Karkera, Jayaprakash D ; Moy, Christopher ; Angibaud, Patrick ; Laquerre, Sylvie ; Lorenzi, Matthew V

Molecular cancer therapeutics, 2017-06, Vol.16 (6), p.1010-1020 [Periódico revisado por pares]

United States: American Association for Cancer Research Inc

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2
Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy
Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy
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Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy

Shamsi, Anas ; Mohammad, Taj ; Anwar, Saleha ; AlAjmi, Mohamed F ; Hussain, Afzal ; Rehman, Md Tabish ; Islam, Asimul ; Hassan, Md Imtaiyaz

Bioscience reports, 2020-06, Vol.40 (6), p.1 [Periódico revisado por pares]

England: Springer Nature B.V

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3
Design and Synthesis of Potent and Multifunctional Aldose Reductase Inhibitors Based on Quinoxalinones
Design and Synthesis of Potent and Multifunctional Aldose Reductase Inhibitors Based on Quinoxalinones
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Design and Synthesis of Potent and Multifunctional Aldose Reductase Inhibitors Based on Quinoxalinones

Qin, Xiangyu ; Hao, Xin ; Han, Hui ; Zhu, Shaojuan ; Yang, Yanchun ; Wu, Bobin ; Hussain, Saghir ; Parveen, Shagufta ; Jing, Chaojun ; Ma, Bing ; Zhu, Changjin

Journal of medicinal chemistry, 2015-02, Vol.58 (3), p.1254-1267 [Periódico revisado por pares]

United States: American Chemical Society

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4
Quinoxaline, its derivatives and applications: A State of the Art review
Quinoxaline, its derivatives and applications: A State of the Art review
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Quinoxaline, its derivatives and applications: A State of the Art review

Pereira, Joana A. ; Pessoa, Ana M. ; Cordeiro, M. Natália D.S. ; Fernandes, Rúben ; Prudêncio, Cristina ; Noronha, João Paulo ; Vieira, Mónica

European journal of medicinal chemistry, 2015-06, Vol.97, p.664-672 [Periódico revisado por pares]

France: Elsevier Masson SAS

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5
Quinoxalinone as a Privileged Platform in Drug Development
Quinoxalinone as a Privileged Platform in Drug Development
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Quinoxalinone as a Privileged Platform in Drug Development

Shi, Leilei ; Hu, Wei ; Wu, Jifeng ; Zhou, Huaiyu ; Zhou, Hua ; Li, Xun

Mini reviews in medicinal chemistry, 2018-02, Vol.18 (5), p.392-413 [Periódico revisado por pares]

Netherlands: Bentham Science Publishers Ltd

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6
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Friedmann Angeli, Jose Pedro ; Schneider, Manuela ; Proneth, Bettina ; Tyurina, Yulia Y ; Tyurin, Vladimir A ; Hammond, Victoria J ; Herbach, Nadja ; Aichler, Michaela ; Walch, Axel ; Eggenhofer, Elke ; Basavarajappa, Devaraj ; Rådmark, Olof ; Kobayashi, Sho ; Seibt, Tobias ; Beck, Heike ; Neff, Frauke ; Esposito, Irene ; Wanke, Rüdiger ; Förster, Heidi ; Yefremova, Olena ; Heinrichmeyer, Marc ; Bornkamm, Georg W ; Geissler, Edward K ; Thomas, Stephen B ; Stockwell, Brent R ; O'Donnell, Valerie B ; Kagan, Valerian E ; Schick, Joel A ; Conrad, Marcus

Nature cell biology, 2014-12, Vol.16 (12), p.1180-1191 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Synthesis and Pesticidal Activities of New Quinoxalines
Synthesis and Pesticidal Activities of New Quinoxalines
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Synthesis and Pesticidal Activities of New Quinoxalines

Liu, Xing-Hai ; Yu, Wei ; Min, Li-Jing ; Wedge, David E ; Tan, Cheng-Xia ; Weng, Jian-Quan ; Wu, Hong-Ke ; Cantrell, Charles L ; Bajsa-Hirschel, Joanna ; Hua, Xue-Wen ; Duke, Stephen O

Journal of agricultural and food chemistry, 2020-07, Vol.68 (28), p.7324-7332 [Periódico revisado por pares]

United States: American Chemical Society

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8
MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants
MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants
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MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants

SUMMA, Vincenzo ; LUDMERER, Steven W ; GATES, Adam T ; GRAHAM, Donald J ; HARPER, Steven ; HAZUDA, Daria J ; MCHALE, Carolyn ; MONTEAGUDO, Edith ; PUCCI, Vincenzo ; ROWLEY, Michael ; RUDD, Michael T ; SORIANO, Aileen ; MCCAULEY, John A ; STAHLHUT, Mark W ; VACCA, Joseph P ; OLSEN, David B ; LIVERTON, Nigel J ; CARROLL, Steven S ; FANDOZZI, Christine ; BURLEIN, Christine ; CLAUDIO, Giuliano ; COLEMAN, Paul J ; DIMUZIO, Jillian M ; FERRARA, Marco ; DI FILIPPO, Marcello

Antimicrobial Agents and Chemotherapy, 2012-08, Vol.56 (8), p.4161-4167 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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9
An Ester‐Substituted Semiconducting Polymer with Efficient Nonradiative Decay Enhances NIR‐II Photoacoustic Performance for Monitoring of Tumor Growth
An Ester‐Substituted Semiconducting Polymer with Efficient Nonradiative Decay Enhances NIR‐II Photoacoustic Performance for Monitoring of Tumor Growth
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An Ester‐Substituted Semiconducting Polymer with Efficient Nonradiative Decay Enhances NIR‐II Photoacoustic Performance for Monitoring of Tumor Growth

Zha, Menglei ; Lin, Xiangwei ; Ni, Jen‐Shyang ; Li, Yaxi ; Zhang, Yachao ; Zhang, Xun ; Wang, Lidai ; Li, Kai

Angewandte Chemie (International ed.), 2020-12, Vol.59 (51), p.23268-23276 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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10
Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion
Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion
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Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

Li, Yang ; Feng, Dongcheng ; Wang, Zhanyu ; Zhao, Yan ; Sun, Ruimin ; Tian, Donghai ; Liu, Deshun ; Zhang, Feng ; Ning, Shili ; Yao, Jihong ; Tian, Xiaofeng

Cell death and differentiation, 2019-11, Vol.26 (11), p.2284-2299 [Periódico revisado por pares]

England: Nature Publishing Group

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