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Material Type: Artigo
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Leukemic cell xenograft in zebrafish embryo for investigating drug efficacyPRUVOT, Benoist ; JACQUEL, Arnaud ; DROIN, Nathalie ; AUBERGER, Patrick ; BOUSCARY, Didier ; TAMBURINI, Jerome ; MULLER, Marc ; FONTENAY, Michaela ; CHLUBA, Johanna ; SOLARY, EricHaematologica (Roma), 2011-04, Vol.96 (4), p.612-616 [Periódico revisado por pares]Pavia: Ferrata Storti FoundationTexto completo disponível |
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Material Type: Artigo
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Mutation in the Sip1 transcription factor leads to a disturbance of the preconditioning of AMPA receptors by episodes of hypoxia in neurons of the cerebral cortex due to changes in their activity and subunit composition. The protective effects of interleukin-10Turovskaya, Maria V. ; Zinchenko, Valery P. ; Babaev, Alexei A. ; Epifanova, Ekaterina A. ; Tarabykin, Victor S. ; Turovsky, Egor A.Archives of biochemistry and biophysics, 2018-09, Vol.654, p.126-135 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Differential Fungicidal Activities of Amphotericin B and Voriconazole against Aspergillus Species Determined by Microbroth MethodologyMELETIADIS, Joseph ; ANTACHOPOULOS, Charalampos ; STERGIOPOULOU, Theodouli ; POURNARAS, Spyros ; ROILIDES, Emmanuel ; WALSH, Thomas JAntimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3329-3337 [Periódico revisado por pares]Washington, DC: American Society for MicrobiologyTexto completo disponível |
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Material Type: Artigo
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Application of sulfoximines in medicinal chemistry from 2013 to 2020Han, Yu ; Xing, Kun ; Zhang, Jian ; Tong, Tong ; Shi, Yuntao ; Cao, Hongxue ; Yu, Huan ; Zhang, Yu ; Liu, Dan ; Zhao, LinxiangEuropean journal of medicinal chemistry, 2021-01, Vol.209, p.112885, Article 112885 [Periódico revisado por pares]France: Elsevier Masson SASTexto completo disponível |
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Material Type: Artigo
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The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunityCanon, Jude ; Rex, Karen ; Saiki, Anne Y ; Mohr, Christopher ; Cooke, Keegan ; Bagal, Dhanashri ; Gaida, Kevin ; Holt, Tyler ; Knutson, Charles G ; Koppada, Neelima ; Lanman, Brian A ; Werner, Jonathan ; Rapaport, Aaron S ; San Miguel, Tisha ; Ortiz, Roberto ; Osgood, Tao ; Sun, Ji-Rong ; Zhu, Xiaochun ; McCarter, John D ; Volak, Laurie P ; Houk, Brett E ; Fakih, Marwan G ; O'Neil, Bert H ; Price, Timothy J ; Falchook, Gerald S ; Desai, Jayesh ; Kuo, James ; Govindan, Ramaswamy ; Hong, David S ; Ouyang, Wenjun ; Henary, Haby ; Arvedson, Tara ; Cee, Victor J ; Lipford, J RussellNature (London), 2019-11, Vol.575 (7781), p.217-223 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Properties of FDA-approved small molecule protein kinase inhibitors: A 2021 updateRoskoski, RobertPharmacological research, 2021-03, Vol.165, p.105463-105463, Article 105463 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosisSJÖBLOM, Tobias ; SHIMIZU, Akira ; O'BRIEN, Kevin P ; PIETRAS, Kristian ; DAL CIN, Paola ; BUCHDUNGER, Elisabeth ; DUMANSKI, Jan P ; ÖSTMAN, Arne ; HELDIN, Carl-HenrikCancer research (Chicago, Ill.), 2001-08, Vol.61 (15), p.5778-5783 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Sotorasib: First ApprovalBlair, Hannah A.Drugs (New York, N.Y.), 2021-09, Vol.81 (13), p.1573-1579 [Periódico revisado por pares]Cham: Springer International PublishingTexto completo disponível |
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Material Type: Artigo
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Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor RegressionZhou, Bing ; Hu, Jiantao ; Xu, Fuming ; Chen, Zhuo ; Bai, Longchuan ; Fernandez-Salas, Ester ; Lin, Mei ; Liu, Liu ; Yang, Chao-Yie ; Zhao, Yujun ; McEachern, Donna ; Przybranowski, Sally ; Wen, Bo ; Sun, Duxin ; Wang, ShaomengJournal of medicinal chemistry, 2018-01, Vol.61 (2), p.462-481 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic LeukemiaByrd, John C ; Furman, Richard R ; Coutre, Steven E ; Flinn, Ian W ; Burger, Jan A ; Blum, Kristie A ; Grant, Barbara ; Sharman, Jeff P ; Coleman, Morton ; Wierda, William G ; Jones, Jeffrey A ; Zhao, Weiqiang ; Heerema, Nyla A ; Johnson, Amy J ; Sukbuntherng, Juthamas ; Chang, Betty Y ; Clow, Fong ; Hedrick, Eric ; Buggy, Joseph J ; James, Danelle F ; O'Brien, SusanThe New England journal of medicine, 2013-07, Vol.369 (1), p.32-42 [Periódico revisado por pares]Waltham, MA: Massachusetts Medical SocietyTexto completo disponível |