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Material Type: Artigo
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Revealing the role of the human blood plasma proteome in obesity using genetic driversZaghlool, Shaza B ; Sharma, Sapna ; Molnar, Megan ; Matías-García, Pamela R ; Elhadad, Mohamed A ; Waldenberger, Melanie ; Peters, Annette ; Rathmann, Wolfgang ; Graumann, Johannes ; Gieger, Christian ; Grallert, Harald ; Suhre, KarstenNature communications, 2021-02, Vol.12 (1), p.1279-13, Article 1279 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Connecting genetic risk to disease end points through the human blood plasma proteomeSuhre, Karsten ; Arnold, Matthias ; Bhagwat, Aditya Mukund ; Cotton, Richard J ; Engelke, Rudolf ; Raffler, Johannes ; Sarwath, Hina ; Thareja, Gaurav ; Wahl, Annika ; DeLisle, Robert Kirk ; Gold, Larry ; Pezer, Marija ; Lauc, Gordan ; El-Din Selim, Mohammed A ; Mook-Kanamori, Dennis O ; Al-Dous, Eman K ; Mohamoud, Yasmin A ; Malek, Joel ; Strauch, Konstantin ; Grallert, Harald ; Peters, Annette ; Kastenmüller, Gabi ; Gieger, Christian ; Graumann, JohannesNature communications, 2017-02, Vol.8 (1), p.14357-14357, Article 14357 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 DiabetesReitmeier, Sandra ; Kiessling, Silke ; Clavel, Thomas ; List, Markus ; Almeida, Eduardo L. ; Ghosh, Tarini S. ; Neuhaus, Klaus ; Grallert, Harald ; Linseisen, Jakob ; Skurk, Thomas ; Brandl, Beate ; Breuninger, Taylor A. ; Troll, Martina ; Rathmann, Wolfgang ; Linkohr, Birgit ; Hauner, Hans ; Laudes, Matthias ; Franke, Andre ; Le Roy, Caroline I. ; Bell, Jordana T. ; Spector, Tim ; Baumbach, Jan ; O’Toole, Paul W. ; Peters, Annette ; Haller, DirkCell host & microbe, 2020-08, Vol.28 (2), p.258-272.e6 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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DNA methylation and body-mass index: a genome-wide analysisDick, Katherine J, PhD ; Nelson, Christopher P, PhD ; Tsaprouni, Loukia, PhD ; Sandling, Johanna K, PhD ; Aïssi, Dylan, MSc ; Wahl, Simone, MSc ; Meduri, Eshwar, PhD ; Morange, Pierre-Emmanuel, Prof ; Gagnon, France, PhD ; Grallert, Harald, PhD ; Waldenberger, Melanie, PhD ; Peters, Annette, Prof ; Erdmann, Jeanette, Prof ; Hengstenberg, Christian, Prof ; Cambien, Francois, Prof ; Goodall, Alison H, Prof ; Ouwehand, Willem H, Prof ; Schunkert, Heribert, Prof ; Thompson, John R, Prof ; Spector, Tim D, FRCP ; Gieger, Christian, PhD ; Trégouët, David-Alexandre, PhD ; Deloukas, Panos, Prof ; Samani, Nilesh J, ProfThe Lancet (British edition), 2014-06, Vol.383 (9933), p.1990-1998 [Periódico revisado por pares]Kidlington: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samplesBreier, Michaela ; Wahl, Simone ; Prehn, Cornelia ; Fugmann, Marina ; Ferrari, Uta ; Weise, Michaela ; Banning, Friederike ; Seissler, Jochen ; Grallert, Harald ; Adamski, Jerzy ; Lechner, Andreas Khan, Rizwan H.PloS one, 2014-02, Vol.9 (2), p.e89728 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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A randomization-based causal inference framework for uncovering environmental exposure effects on human gut microbiotaSommer, Alice J ; Peters, Annette ; Rommel, Martina ; Cyrys, Josef ; Grallert, Harald ; Haller, Dirk ; Müller, Christian L ; Bind, Marie-Abèle C Anders, SimonPLoS computational biology, 2022-05, Vol.18 (5), p.e1010044-e1010044 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategiesDo, Kieu Trinh ; Wahl, Simone ; Raffler, Johannes ; Molnos, Sophie ; Laimighofer, Michael ; Adamski, Jerzy ; Suhre, Karsten ; Strauch, Konstantin ; Peters, Annette ; Gieger, Christian ; Langenberg, Claudia ; Stewart, Isobel D. ; Theis, Fabian J. ; Grallert, Harald ; Kastenmüller, Gabi ; Krumsiek, JanMetabolomics, 2018-10, Vol.14 (10), p.128-18, Article 128 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Material Type: Artigo
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Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing studyRauch, Anita, Prof ; Wieczorek, Dagmar, MD ; Graf, Elisabeth, MSc ; Wieland, Thomas, MSc ; Endele, Sabine, PhD ; Schwarzmayr, Thomas, MSc ; Albrecht, Beate, MD ; Bartholdi, Deborah, MD ; Beygo, Jasmin, MSc ; Di Donato, Nataliya, MD ; Dufke, Andreas, MD ; Cremer, Kirsten, MD ; Hempel, Maja, MD ; Horn, Denise, MD ; Hoyer, Juliane, MD ; Joset, Pascal, PhD ; Röpke, Albrecht, PhD ; Moog, Ute, MD ; Riess, Angelika, MD ; Thiel, Christian T, MD ; Tzschach, Andreas, MD ; Wiesener, Antje, MD ; Wohlleber, Eva, MD ; Zweier, Christiane, MD ; Ekici, Arif B, PhD ; Zink, Alexander M, MSc ; Rump, Andreas, PhD ; Meisinger, Christa, MD ; Grallert, Harald, PhD ; Sticht, Heinrich, PhD ; Schenck, Annette, PhD ; Engels, Hartmut, PhD ; Rappold, Gudrun, Prof ; Schröck, Evelin, Prof ; Wieacker, Peter, Prof ; Riess, Olaf, Prof ; Meitinger, Thomas, Prof ; Reis, André, Prof ; Strom, Tim M, DrThe Lancet (British edition), 2012-11, Vol.380 (9854), p.1674-1682 [Periódico revisado por pares]Kidlington: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Novel biomarkers for pre‐diabetes identified by metabolomicsWang‐Sattler, Rui ; Yu, Zhonghao ; Herder, Christian ; Messias, Ana C ; Floegel, Anna ; He, Ying ; Heim, Katharina ; Campillos, Monica ; Holzapfel, Christina ; Thorand, Barbara ; Grallert, Harald ; Xu, Tao ; Bader, Erik ; Huth, Cornelia ; Mittelstrass, Kirstin ; Döring, Angela ; Meisinger, Christa ; Gieger, Christian ; Prehn, Cornelia ; Roemisch‐Margl, Werner ; Carstensen, Maren ; Xie, Lu ; Yamanaka‐Okumura, Hisami ; Xing, Guihong ; Ceglarek, Uta ; Thiery, Joachim ; Giani, Guido ; Lickert, Heiko ; Lin, Xu ; Li, Yixue ; Boeing, Heiner ; Joost, Hans‐Georg ; de Angelis, Martin Hrabé ; Rathmann, Wolfgang ; Suhre, Karsten ; Prokisch, Holger ; Peters, Annette ; Meitinger, Thomas ; Roden, Michael ; Wichmann, H‐Erich ; Pischon, Tobias ; Adamski, Jerzy ; Illig, ThomasMolecular systems biology, 2012, Vol.8 (1), p.615-615 [Periódico revisado por pares]Texto completo disponível |
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Material Type: Artigo
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Human genome diversity data reveal that L564P is the predominant TPC2 variant and a prerequisite for the blond hair associated M484L gain-of-function effectBöck, Julia ; Krogsaeter, Einar ; Passon, Marcel ; Chao, Yu-Kai ; Sharma, Sapna ; Grallert, Harald ; Peters, Annette ; Grimm, Christian Oancea, ElenaPLoS genetics, 2021-01, Vol.17 (1), p.e1009236 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |