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1
Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation
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Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation

Matthews, Erin E. ; Thévenin, Damien ; Rogers, Julia M. ; Gotow, Lisa ; Lira, Paul D. ; Reiter, Lawrence A. ; Brissette, William H. ; Engelman, Donald M.

The FASEB journal, 2011-07, Vol.25 (7), p.2234-2244 [Periódico revisado por pares]

United States: Federation of American Societies for Experimental Biology

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2
Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity
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Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity

Fisher, Timothy S. ; Kamperschroer, Cris ; Oliphant, Theodore ; Love, Victoria A. ; Lira, Paul D. ; Doyonnas, Regis ; Bergqvist, Simon ; Baxi, Sangita M. ; Rohner, Allison ; Shen, Amy C. ; Huang, Chunli ; Sokolowski, Sharon A. ; Sharp, Leslie L.

Cancer Immunology, Immunotherapy, 2012-10, Vol.61 (10), p.1721-1733 [Periódico revisado por pares]

Berlin/Heidelberg: Springer-Verlag

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3
CP-481,715, a Potent and Selective CCR1 Antagonist with Potential Therapeutic Implications for Inflammatory Diseases
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CP-481,715, a Potent and Selective CCR1 Antagonist with Potential Therapeutic Implications for Inflammatory Diseases

Gladue, Ronald P. ; Tylaska, Laurie A. ; Brissette, William H. ; Lira, Paul D. ; Kath, John C. ; Poss, Christopher S. ; Brown, Matthew F. ; Paradis, Timothy J. ; Conklyn, Maryrose J. ; Ogborne, Kevin T. ; McGlynn, Molly A. ; Lillie, Brett M. ; DiRico, Amy P. ; Mairs, Erin N. ; McElroy, Eric B. ; Martin, William H. ; Stock, Ingrid A. ; Shepard, Richard M. ; Showell, Henry J. ; Neote, Kuldeep

The Journal of biological chemistry, 2003-10, Vol.278 (42), p.40473-40480 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Impaired Invariant Chain Degradation and Antigen Presentation and Diminished Collagen-Induced Arthritis in Cathepsin S Null Mice
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Impaired Invariant Chain Degradation and Antigen Presentation and Diminished Collagen-Induced Arthritis in Cathepsin S Null Mice

Nakagawa, Terry Y ; Brissette, William H ; Lira, Paul D ; Griffiths, Richard J ; Petrushova, Nina ; Stock, Jeffrey ; McNeish, John D ; Eastman, Susan E ; Howard, Edward D ; Clarke, Sally R.M ; Rosloniec, Edward F ; Elliott, Eileen A ; Rudensky, Alexander Y

Immunity (Cambridge, Mass.), 1999-02, Vol.10 (2), p.207-217 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Piperazinyl CCR1 antagonists—optimization of human liver microsome stability
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Piperazinyl CCR1 antagonists—optimization of human liver microsome stability

Brown, Matthew F. ; Bahnck, Kevin B. ; Blumberg, Laura C. ; Brissette, William H. ; Burrell, Sara A. ; Driscoll, James P. ; Fedeles, Flavia ; Fisher, Michael B. ; Foti, Robert S. ; Gladue, Ronald P. ; Guzman-Martinez, Aikomari ; Hayward, Matthew M. ; Lira, Paul D. ; Lillie, Brett M. ; Lu, Yi ; Lundquist, Greg D. ; McElroy, Eric B. ; McGlynn, Molly A. ; Paradis, Timothy J. ; Poss, Christopher S. ; Roache, James H. ; Shavnya, Andrei ; Shepard, Richard M. ; Trevena, Kristen A. ; Tylaska, Laurie A.

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3109-3112 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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6
Analysis of the role of the HIF hydroxylase family members in erythropoiesis
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Analysis of the role of the HIF hydroxylase family members in erythropoiesis

Fisher, Timothy S. ; Lira, Paul D. ; Stock, Jeffrey L. ; Perregaux, David G. ; Brissette, William H. ; Ozolinš, Terence R.S. ; Li, Baiyong

Biochemical and biophysical research communications, 2009-10, Vol.388 (4), p.683-688 [Periódico revisado por pares]

United States: Elsevier Inc

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7
The identification of orally bioavailable thrombopoietin agonists
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The identification of orally bioavailable thrombopoietin agonists

Munchhof, Michael J. ; Antipas, Amy S. ; Blumberg, Laura C. ; Brissette, William H. ; Brown, Matthew F. ; Casavant, Jeffrey M. ; Doty, Jonathan L. ; Driscoll, James ; Harris, Thomas M. ; Wolf-Gouveia, Lilli A. ; Jones, Christopher S. ; Li, Qifang ; Linde, Robert G. ; Lira, Paul D. ; Marfat, Anthony ; McElroy, Eric ; Mitton-Fry, Mark ; McCurdy, Sandra P. ; Reiter, Lawrence A. ; Ripp, Sharon L. ; Shavnya, Andrei ; Thomasco, Lisa M. ; Trevena, Kristen A.

Bioorganic & medicinal chemistry letters, 2009-03, Vol.19 (5), p.1428-1430 [Periódico revisado por pares]

England: Elsevier Ltd

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8
Pyrimidine benzamide-based thrombopoietin receptor agonists
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Pyrimidine benzamide-based thrombopoietin receptor agonists

Reiter, Lawrence A. ; Subramanyam, Chakrapani ; Mangual, Emilio J. ; Jones, Christopher S. ; Smeets, Marc I. ; Brissette, William H. ; McCurdy, Sandra P. ; Lira, Paul D. ; Linde, Robert G. ; Li, Qifang ; Zhang, Fangning ; Antipas, Amy S. ; Blumberg, Laura C. ; Doty, Jonathan L. ; Driscoll, James P. ; Munchhof, Michael J. ; Ripp, Sharon L. ; Shavnya, Andrei ; Shepard, Richard M. ; Sperger, Diana ; Thomasco, Lisa M. ; Trevena, Kristen A. ; Wolf-Gouveia, Lilli A. ; Zhang, Liling

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (19), p.5447-5454 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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9
Novel CCR1 antagonists with improved metabolic stability
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Novel CCR1 antagonists with improved metabolic stability

BROWN, Matthew F ; AVERY, Mike ; LIRA, Paul D ; LILLIE, Brett M ; LUNDQUIST, Greg D ; MAIRS, Erin N ; MCELROY, Eric B ; MCGLYNN, Molly A ; PARADIS, Timothy J ; POSS, Christopher S ; ROSSULEK, Michelle I ; SHEPARD, Richard M ; BRISSETTE, William H ; SIMS, Jeff ; STRELEVITZ, Timothy J ; TRUESDELL, Susan ; TYLASKA, Laurie A ; YOON, Kwansik ; DEYE ZHENG ; CHANG, J. H ; COLIZZA, Kevin ; CONKLYN, Maryrose ; DIRICO, Amy P ; GLADUE, Ronald P ; KATH, John C ; KRUEGER, Suzanne S

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2175-2179 [Periódico revisado por pares]

Oxford: Elsevier

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10
Potent small molecule CCR1 antagonists
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Potent small molecule CCR1 antagonists

KATH, John C ; BRISSETTE, William H ; MARTIN, William H ; MCELROY, Eric B ; MCGLYNN, Molly A ; PARADIS, Timothy J ; POSS, Christopher S ; STOCK, Ingrid A ; TYLASKA, Laurie A ; DEYE ZHENG ; BROWN, Matthew F ; CONKLYN, Maryrose ; DIRICO, Amy P ; DORFF, Peter ; GLADUE, Ronald P ; LILLIE, Brett M ; LIRA, Paul D ; MAIRS, Erin N

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2169-2173 [Periódico revisado por pares]

Oxford: Elsevier

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