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Structure−Activity Relationships of Truncated d- and l-4′-Thioadenosine Derivatives as Species-Independent A3 Adenosine Receptor Antagonists
Structure−Activity Relationships of Truncated d- and l-4′-Thioadenosine Derivatives as Species-Independent A3 Adenosine Receptor Antagonists
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Structure−Activity Relationships of Truncated d- and l-4′-Thioadenosine Derivatives as Species-Independent A3 Adenosine Receptor Antagonists

Jeong, Lak Shin ; Pal, Shantanu ; Choe, Seung Ah ; Choi, Won Jun ; Jacobson, Kenneth A ; Gao, Zhan-Guo ; Klutz, Athena M ; Hou, Xiyan ; Kim, Hea Ok ; Lee, Hyuk Woo ; Lee, Sang Kook ; Tosh, Dilip K ; Moon, Hyung Ryong

Journal of medicinal chemistry, 2008-10, Vol.51 (20), p.6609-6613 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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2
N 6‑Substituted 5′‑N‑Methylcarbamoyl-4′-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation
N 6‑Substituted 5′‑N‑Methylcarbamoyl-4′-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation
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N 6‑Substituted 5′‑N‑Methylcarbamoyl-4′-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation

Yu, Jinha ; Zhao, Long Xuan ; Park, Jongmi ; Lee, Hyuk Woo ; Sahu, Pramod K ; Cui, Minghua ; Moss, Steven M ; Hammes, Eva ; Warnick, Eugene ; Gao, Zhan-Guo ; Noh, Minsoo ; Choi, Sun ; Ahn, Hee-Chul ; Choi, Jungwon ; Jacobson, Kenneth A ; Jeong, Lak Shin

Journal of medicinal chemistry, 2017-04, Vol.60 (8), p.3422-3437 [Periódico revisado por pares]

American Chemical Society

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3
Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists
Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists
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Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists

Nayak, Akshata ; Chandra, Girish ; Hwang, Inah ; Kim, Kyunglim ; Hou, Xiyan ; Kim, Hea Ok ; Sahu, Pramod K ; Roy, Kuldeep K ; Yoo, Jakyung ; Lee, Yoonji ; Cui, Minghua ; Choi, Sun ; Moss, Steven M ; Phan, Khai ; Gao, Zhan-Guo ; Ha, Hunjoo ; Jacobson, Kenneth A ; Jeong, Lak Shin

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1344-1354 [Periódico revisado por pares]

United States

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4
N 6 -Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A 3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation
N 6 -Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A 3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation
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N 6 -Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A 3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation

Yu, Jinha ; Zhao, Long Xuan ; Park, Jongmi ; Lee, Hyuk Woo ; Sahu, Pramod K ; Cui, Minghua ; Moss, Steven M ; Hammes, Eva ; Warnick, Eugene ; Gao, Zhan-Guo ; Noh, Minsoo ; Choi, Sun ; Ahn, Hee-Chul ; Choi, Jungwon ; Jacobson, Kenneth A ; Jeong, Lak Shin

Journal of medicinal chemistry, 2017-04, Vol.60 (8), p.3422-3437 [Periódico revisado por pares]

United States

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5
N6-Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation
N6-Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation
Material Type:
Artigo 		Adicionar ao Meu Espaço

N6-Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation

Yu, Jinha ; Zhao, Long Xuan ; Park, Jongmi ; Lee, Hyuk Woo ; Sahu, Pramod K ; Cui, Minghua ; Moss, Steven M ; Hammes, Eva ; Warnick, Eugene ; Gao, Zhan-Guo ; Noh, Minsoo ; Choi, Sun ; Ahn, Hee-Chul ; Choi, Jungwon ; Jacobson, Kenneth A ; Jeong, Lak Shin

Journal of medicinal chemistry, 2017-04, Vol.60 (8), p.3422-3437 [Periódico revisado por pares]

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6
Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety
Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety
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Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety

GAO, Zhan-Guo ; JOSHI, Bhalchandra V ; KLUTZ, Athena M ; KIM, Soo-Kyung ; HYUK WOO LEE ; HEA OK KIM ; LAK SHIN JEONG ; JACOBSON, Kenneth A

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (3), p.596-601 [Periódico revisado por pares]

Oxford: Elsevier

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7
Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species
Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species
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Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species

Wang, Zhao ; Do, Chi Wai ; Avila, Marcel Y ; Peterson-Yantorno, Kim ; Stone, Richard A ; Gao, Zhan-Guo ; Joshi, Bhalchandra ; Besada, Pedro ; Jeong, Lak Shin ; Jacobson, Kenneth A ; Civan, Mortimer M

Experimental eye research, 2010-01, Vol.90 (1), p.146-154 [Periódico revisado por pares]

England

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8
Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl- N 6 -Substituted-( N )-Methanocarba-nucleosides as A 3 Adenosine Receptor Antagonists and Partial Agonists
Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl- N 6 -Substituted-( N )-Methanocarba-nucleosides as A 3 Adenosine Receptor Antagonists and Partial Agonists
Material Type:
Artigo 		Adicionar ao Meu Espaço

Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl- N 6 -Substituted-( N )-Methanocarba-nucleosides as A 3 Adenosine Receptor Antagonists and Partial Agonists

Nayak, Akshata ; Chandra, Girish ; Hwang, Inah ; Kim, Kyunglim ; Hou, Xiyan ; Kim, Hea Ok ; Sahu, Pramod K. ; Roy, Kuldeep K. ; Yoo, Jakyung ; Lee, Yoonji ; Cui, Minghua ; Choi, Sun ; Moss, Steven M. ; Phan, Khai ; Gao, Zhan-Guo ; Ha, Hunjoo ; Jacobson, Kenneth A. ; Jeong, Lak Shin

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1344-1354 [Periódico revisado por pares]

Texto completo disponível

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9
Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl-N6-Substituted-(N)-Methanocarba-nucleosides as A3 Adenosine Receptor Antagonists and Partial Agonists
Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl-N6-Substituted-(N)-Methanocarba-nucleosides as A3 Adenosine Receptor Antagonists and Partial Agonists
Material Type:
Artigo 		Adicionar ao Meu Espaço

Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl-N6-Substituted-(N)-Methanocarba-nucleosides as A3 Adenosine Receptor Antagonists and Partial Agonists

Nayak, Akshata ; Chandra, Girish ; Hwang, Inah ; Kim, Kyunglim ; Hou, Xiyan ; Kim, Hea Ok ; Sahu, Pramod K. ; Roy, Kuldeep K. ; Yoo, Jakyung ; Lee, Yoonji ; Cui, Minghua ; Choi, Sun ; Moss, Steven M. ; Phan, Khai ; Gao, Zhan-Guo ; Ha, Hunjoo ; Jacobson, Kenneth A. ; Jeong, Lak Shin

Journal of medicinal chemistry, 2014-01, Vol.57 (4), p.1344-1354 [Periódico revisado por pares]

American Chemical Society

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10
Nucleoside-derived antagonists to A 3 adenosine receptors lower mouse intraocular pressure and act across species
Nucleoside-derived antagonists to A 3 adenosine receptors lower mouse intraocular pressure and act across species
Material Type:
Artigo 		Adicionar ao Meu Espaço

Nucleoside-derived antagonists to A 3 adenosine receptors lower mouse intraocular pressure and act across species

Wang, Zhao ; Do, Chi Wai ; Avila, Marcel Y. ; Peterson-Yantorno, Kim ; Stone, Richard A. ; Gao, Zhan-Guo ; Joshi, Bhalchandra ; Besada, Pedro ; Jeong, Lak Shin ; Jacobson, Kenneth A. ; Civan, Mortimer M.

Experimental eye research, 2010, Vol.90 (1), p.146-154 [Periódico revisado por pares]

Elsevier Ltd

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