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1
Nonclinical Safety Evaluation of scAAV8- RLBP1 for Treatment of RLBP1 Retinitis Pigmentosa
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Nonclinical Safety Evaluation of scAAV8- RLBP1 for Treatment of RLBP1 Retinitis Pigmentosa

MacLachlan, Timothy K ; Milton, Mark N ; Turner, Oliver ; Tukov, Francis ; Choi, Vivian W ; Penraat, Jan ; Delmotte, Marie-Hélène ; Michaut, Lydia ; Jaffee, Bruce D ; Bigelow, Chad E

Molecular therapy. Methods & clinical development, 2018-03, Vol.8 (C), p.105-120 [Periódico revisado por pares]

United States: Elsevier Limited

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2
BRCA1 Effects on the Cell Cycle and the DNA Damage Response Are Linked to Altered Gene Expression
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BRCA1 Effects on the Cell Cycle and the DNA Damage Response Are Linked to Altered Gene Expression

MacLachlan, Timothy K. ; Somasundaram, Kumaravel ; Sgagias, Magda ; Shifman, Yelena ; Muschel, Ruth J. ; Cowan, Kenneth H. ; El-Deiry, Wafik S.

The Journal of biological chemistry, 2000-01, Vol.275 (4), p.2777-2785 [Periódico revisado por pares]

United States: Elsevier Inc

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3
P886: AFRICAN AMERICAN PATIENTS WITH SMOLDERING MULTIPLE MYELOMA MAY HAVE A LOWER RISK OF PROGRESSION COMPARED TO WHITE PATIENTS
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P886: AFRICAN AMERICAN PATIENTS WITH SMOLDERING MULTIPLE MYELOMA MAY HAVE A LOWER RISK OF PROGRESSION COMPARED TO WHITE PATIENTS

Akhlaghi, T. ; Maclachlan, K. ; Korde, N. ; Mailankody, S. ; Lesokhin, A. ; Hassoun, H. ; Lu, S. X. ; Patel, D. ; Shah, U. ; Tan, C. ; Derkach, A. ; Lahoud, O. ; Landau, H. J. ; Shah, G. L. ; Scordo, M. ; Chung, D. J. ; Giralt, S. A. ; Usmani, S. Z. ; Landgren, O. ; Hultcrantz, M.

HemaSphere, 2022-06, Vol.6 (Suppl), p.778-779 [Periódico revisado por pares]

Philadelphia, PA: Lippincott Williams & Wilkins

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4
S177: EVALUATING SERUM FREE LIGHT CHAIN RATIO AS A BIOMARKER FOR MULTIPLE MYELOMA
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S177: EVALUATING SERUM FREE LIGHT CHAIN RATIO AS A BIOMARKER FOR MULTIPLE MYELOMA

Akhlaghi, T. ; Maclachlan, K. ; Korde, N. ; Mailankody, S. ; Lesokhin, A. ; Hassoun, H. ; Lu, S. X. ; Patel, D. ; Shah, U. ; Tan, C. ; Derkach, A. ; Lahoud, O. ; Landau, H. J. ; Shah, G. L. ; Scordo, M. ; Chung, D. J. ; Giralt, S. A. ; Usmani, S. Z. ; Landgren, O. ; Hultcrantz, M.

HemaSphere, 2022-06, Vol.6, p.78-79 [Periódico revisado por pares]

Philadelphia, PA: Lippincott Williams & Wilkins

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5
Challenges and opportunities for the future of monoclonal antibody development: Improving safety assessment and reducing animal use
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Challenges and opportunities for the future of monoclonal antibody development: Improving safety assessment and reducing animal use

Sewell, Fiona ; Chapman, Kathryn ; Couch, Jessica ; Dempster, Maggie ; Heidel, Shawn ; Loberg, Lise ; Maier, Curtis ; Maclachlan, Timothy K ; Todd, Marque ; van der Laan, Jan Willem

mAbs, 2017-07, Vol.9 (5), p.742-755 [Periódico revisado por pares]

United States: Taylor & Francis

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6
BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation
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BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation

Takimoto, Rishu ; MacLachlan, Timothy K. ; Dicker, David T. ; Niitsu, Yoshiro ; Mori, Toshio ; El-Deiry, Wafik S.

Cancer biology & therapy, 2002-03, Vol.1 (2), p.177-186 [Periódico revisado por pares]

United States: Taylor & Francis

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7
Repression of BRCA1 through a Feedback Loop Involving p53
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Repression of BRCA1 through a Feedback Loop Involving p53

MacLachlan, Timothy K. ; Dash, Bipin C. ; Dicker, David T. ; El-Deiry, Wafik S.

The Journal of biological chemistry, 2000-10, Vol.275 (41), p.31869-31875 [Periódico revisado por pares]

United States: Elsevier Inc

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8
BRCA1 Augments Transcription by the NF-κB Transcription Factor by Binding to the Rel Domain of the p65/RelA Subunit
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BRCA1 Augments Transcription by the NF-κB Transcription Factor by Binding to the Rel Domain of the p65/RelA Subunit

Benezra, Miriam ; Chevallier, Nathalie ; Morrison, Debra J. ; MacLachlan, Timothy K. ; El-Deiry, Wafik S. ; Licht, Jonathan D.

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.26333-26341 [Periódico revisado por pares]

Elsevier Inc

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9
Marine-derived cancer therapeutics making a splash
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Marine-derived cancer therapeutics making a splash

MacLachlan, Timothy K. ; Pinkas, Jan

Cancer biology & therapy, 2005-08, Vol.4 (8), p.883-884 [Periódico revisado por pares]

United States: Taylor & Francis

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10
A Unique Domain of pRb2/p130 Acts as an Inhibitor of Cdk2 Kinase Activity
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A Unique Domain of pRb2/p130 Acts as an Inhibitor of Cdk2 Kinase Activity

De Luca, Antonio ; MacLachlan, Timothy K. ; Bagella, Luigi ; Dean, Charity ; Howard, Candace M. ; Claudio, Pier Paolo ; Baldi, Alfonso ; Khalili, Kamel ; Giordano, Antonio

The Journal of biological chemistry, 1997-08, Vol.272 (34), p.20971-20974 [Periódico revisado por pares]

United States: Elsevier Inc

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