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1
The leukocytes expressing DARPP-32 are reduced in patients with schizophrenia and bipolar disorder
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The leukocytes expressing DARPP-32 are reduced in patients with schizophrenia and bipolar disorder

Torres, K.C.L. ; Souza, B.R. ; Miranda, D.M. ; Nicolato, R. ; Neves, F.S. ; Barros, A.G.A. ; Dutra, W.O. ; Gollob, K.J. ; Correa, H. ; Romano-Silva, M.A.

Progress in neuro-psychopharmacology & biological psychiatry, 2009-03, Vol.33 (2), p.214-219 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

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2
Expression of neuronal calcium sensor-1 (NCS-1) is decreased in leukocytes of schizophrenia and bipolar disorder patients
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Expression of neuronal calcium sensor-1 (NCS-1) is decreased in leukocytes of schizophrenia and bipolar disorder patients

Torres, K.C.L. ; Souza, B.R. ; Miranda, D.M. ; Sampaio, A.M. ; Nicolato, R. ; Neves, F.S. ; Barros, A.G.A. ; Dutra, W.O. ; Gollob, K.J. ; Correa, H. ; Romano-Silva, M.A.

Progress in neuro-psychopharmacology & biological psychiatry, 2009-03, Vol.33 (2), p.229-234 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

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3
Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor
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Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

Stepan, Antonia F ; Subramanyam, Chakrapani ; Efremov, Ivan V ; Dutra, Jason K ; O’Sullivan, Theresa J ; DiRico, Kenneth J ; McDonald, W. Scott ; Won, Annie ; Dorff, Peter H ; Nolan, Charles E ; Becker, Stacey L ; Pustilnik, Leslie R ; Riddell, David R ; Kauffman, Gregory W ; Kormos, Bethany L ; Zhang, Liming ; Lu, Yasong ; Capetta, Steven H ; Green, Michael E ; Karki, Kapil ; Sibley, Evelyn ; Atchison, Kevin P ; Hallgren, Andrew J ; Oborski, Christine E ; Robshaw, Ashley E ; Sneed, Blossom ; O’Donnell, Christopher J

Journal of medicinal chemistry, 2012-04, Vol.55 (7), p.3414-3424 [Periódico revisado por pares]

United States: American Chemical Society

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4
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
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Artigo
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Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation

O’Neill, Brian T ; Beck, Elizabeth M ; Butler, Christopher R ; Nolan, Charles E ; Gonzales, Cathleen ; Zhang, Lei ; Doran, Shawn D ; Lapham, Kimberly ; Buzon, Leanne M ; Dutra, Jason K ; Barreiro, Gabriela ; Hou, Xinjun ; Martinez-Alsina, Luis A ; Rogers, Bruce N ; Villalobos, Anabella ; Murray, John C ; Ogilvie, Kevin ; LaChapelle, Erik A ; Chang, Cheng ; Lanyon, Lorraine F ; Steppan, Claire M ; Robshaw, Ashley ; Hales, Katherine ; Boucher, Germaine G ; Pandher, Karamjeet ; Houle, Christopher ; Ambroise, Claude W ; Karanian, David ; Riddell, David ; Bales, Kelly R ; Brodney, Michael A

Journal of medicinal chemistry, 2018-05, Vol.61 (10), p.4476-4504 [Periódico revisado por pares]

United States: American Chemical Society

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5
Pharmacological evaluation of clinically relevant concentrations of (2R,6R)-hydroxynorketamine
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Pharmacological evaluation of clinically relevant concentrations of (2R,6R)-hydroxynorketamine

Shaffer, Christopher L. ; Dutra, Jason K. ; Tseng, Wei Chou ; Weber, Mark L. ; Bogart, Luke J. ; Hales, Katherine ; Pang, Jincheng ; Volfson, Dmitri ; am Ende, Christopher W. ; Green, Michael E. ; Buhl, Derek L.

Neuropharmacology, 2019-07, Vol.153, p.73-81 [Periódico revisado por pares]

England: Elsevier Ltd

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6
Fluorophosphonates on‐Demand: A General and Simplified Approach toward Fluorophosphonate Synthesis
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Fluorophosphonates on‐Demand: A General and Simplified Approach toward Fluorophosphonate Synthesis

Dutra, Jason K. ; Foley, Timothy L. ; Huang, Zhen ; Fisher, Ethan L. ; Lachapelle, Erik A. ; Mahapatra, Subham ; Ogilvie, Kevin ; Butler, Todd W. ; Bellenger, Justin ; Devraj Majmudar, Jaimeen ; am Ende, Christopher W.

Chembiochem : a European journal of chemical biology, 2021-05, Vol.22 (10), p.1769-1774 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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7
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε
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Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε

de Souza Gama, Fernando H ; Dutra, Luiz A ; Hawgood, Michael ; Dos Reis, Caio Vinícius ; Serafim, Ricardo A M ; Ferreira, Jr, Marcos A ; Teodoro, Bruno V M ; Takarada, Jéssica Emi ; Santiago, André S ; Balourdas, Dimitrios-Ilias ; Nilsson, Ann-Sofie ; Urien, Bruno ; Almeida, Vitor M ; Gileadi, Carina ; Ramos, Priscila Z ; Salmazo, Anita ; Vasconcelos, Stanley N S ; Cunha, Micael R ; Mueller, Susanne ; Knapp, Stefan ; Massirer, Katlin B ; Elkins, Jonathan M ; Gileadi, Opher ; Mascarello, Alessandra ; Lemmens, Bennie B L G ; Guimarães, Cristiano R W ; Azevedo, Hatylas ; Couñago, Rafael M

Journal of medicinal chemistry, 2024-05 [Periódico revisado por pares]

United States

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8
Population Pharmacokinetics of Levofloxacin, Gatifloxacin, and Moxifloxacin in Adults with Pulmonary Tuberculosis
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Population Pharmacokinetics of Levofloxacin, Gatifloxacin, and Moxifloxacin in Adults with Pulmonary Tuberculosis

PELOQUIN, Charles A ; HADAD, David Jamil ; MOLINO, Lucilia Pereira Dutra ; PALACI, Moises ; BOOM, W. Henry ; DIETZE, Reynaldo ; JOHNSON, John L

Antimicrobial Agents and Chemotherapy, 2008-03, Vol.52 (3), p.852-857 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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9
Trifluoromethyl Oxetanes: Synthesis and Evaluation as a tert‐Butyl Isostere
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Trifluoromethyl Oxetanes: Synthesis and Evaluation as a tert‐Butyl Isostere

Mukherjee, Paramita ; Pettersson, Martin ; Dutra, Jason K. ; Xie, Longfei ; am Ende, Christopher W.

ChemMedChem, 2017-10, Vol.12 (19), p.1574-1577 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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10
Fluorophosphonate‐Based Degrader Identifies Degradable Serine Hydrolases by Quantitative Proteomics
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Fluorophosphonate‐Based Degrader Identifies Degradable Serine Hydrolases by Quantitative Proteomics

Field, S. Denise ; Lee, Wankyu ; Dutra, Jason K. ; Serneo, Finley Scott F. ; Oyer, Jon ; Xu, Hua ; Johnson, Douglas S. ; am Ende, Christopher W. ; Seneviratne, Uthpala

Chembiochem : a European journal of chemical biology, 2020-10, Vol.21 (20), p.2916-2920 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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