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CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression
CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression
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CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression

Guo, Yanxia ; Walsh, Alice M ; Fearon, Ursula ; Smith, Malcolm D ; Wechalekar, Mihir D ; Yin, Xuefeng ; Cole, Suzanne ; Orr, Carl ; McGarry, Trudy ; Canavan, Mary ; Kelly, Stephan ; Lin, Tai-An ; Liu, Xuejun ; Proudman, Susanna M ; Veale, Douglas J ; Pitzalis, Costantino ; Nagpal, Sunil

The Journal of immunology (1950), 2017-06, Vol.198 (11), p.4490-4501 [Periódico revisado por pares]

United States: American Association of Immunologists

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2
cDC1 prime and are licensed by CD4 + T cells to induce anti-tumour immunity
cDC1 prime and are licensed by CD4 + T cells to induce anti-tumour immunity
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cDC1 prime and are licensed by CD4 + T cells to induce anti-tumour immunity

Ferris, Stephen T ; Durai, Vivek ; Wu, Renee ; Theisen, Derek J ; Ward, Jeffrey P ; Bern, Michael D ; Davidson, 4th, Jesse T ; Bagadia, Prachi ; Liu, Tiantian ; Briseño, Carlos G ; Li, Lijin ; Gillanders, William E ; Wu, Gregory F ; Yokoyama, Wayne M ; Murphy, Theresa L ; Schreiber, Robert D ; Murphy, Kenneth M

Nature (London), 2020-08, Vol.584 (7822), p.624-629 [Periódico revisado por pares]

England: Nature Publishing Group

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3
CXCR5 + PD-1 + follicular helper CD8 T cells control B cell tolerance
CXCR5 + PD-1 + follicular helper CD8 T cells control B cell tolerance
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CXCR5 + PD-1 + follicular helper CD8 T cells control B cell tolerance

Chen, Yuhong ; Yu, Mei ; Zheng, Yongwei ; Fu, Guoping ; Xin, Gang ; Zhu, Wen ; Luo, Lan ; Burns, Robert ; Li, Quan-Zhen ; Dent, Alexander L ; Zhu, Nan ; Cui, Weiguo ; Malherbe, Laurent ; Wen, Renren ; Wang, Demin

Nature communications, 2019-09, Vol.10 (1), p.4415-15, Article 4415 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Monitoring T cell-dendritic cell interactions in vivo by intercellular enzymatic labelling
Monitoring T cell-dendritic cell interactions in vivo by intercellular enzymatic labelling
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Monitoring T cell-dendritic cell interactions in vivo by intercellular enzymatic labelling

Pasqual, Giulia ; Chudnovskiy, Aleksey ; Tas, Jeroen M J ; Agudelo, Marianna ; Schweitzer, Lawrence D ; Cui, Ang ; Hacohen, Nir ; Victora, Gabriel D

Nature (London), 2018-01, Vol.553 (7689), p.496-500 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Designed proteins assemble antibodies into modular nanocages
Designed proteins assemble antibodies into modular nanocages
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Designed proteins assemble antibodies into modular nanocages

Divine, Robby ; Dang, Ha V ; Ueda, George ; Fallas, Jorge A ; Vulovic, Ivan ; Sheffler, William ; Saini, Shally ; Zhao, Yan Ting ; Raj, Infencia Xavier ; Morawski, Peter A ; Jennewein, Madeleine F ; Homad, Leah J ; Wan, Yu-Hsin ; Tooley, Marti R ; Seeger, Franziska ; Etemadi, Ali ; Fahning, Mitchell L ; Lazarovits, James ; Roederer, Alex ; Walls, Alexandra C ; Stewart, Lance ; Mazloomi, Mohammadali ; King, Neil P ; Campbell, Daniel J ; McGuire, Andrew T ; Stamatatos, Leonidas ; Ruohola-Baker, Hannele ; Mathieu, Julie ; Veesler, David ; Baker, David

Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6537), p.47 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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6
CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study
CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study
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CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study

O'Hara, Mark H ; O'Reilly, Eileen M ; Varadhachary, Gauri ; Wolff, Robert A ; Wainberg, Zev A ; Ko, Andrew H ; Fisher, George ; Rahma, Osama ; Lyman, Jaclyn P ; Cabanski, Christopher R ; Mick, Rosemarie ; Gherardini, Pier Federico ; Kitch, Lacey J ; Xu, Jingying ; Samuel, Theresa ; Karakunnel, Joyson ; Fairchild, Justin ; Bucktrout, Samantha ; LaVallee, Theresa M ; Selinsky, Cheryl ; Till, Jacob E ; Carpenter, Erica L ; Alanio, Cécile ; Byrne, Katelyn T ; Chen, Richard O ; Trifan, Ovid C ; Dugan, Ute ; Horak, Christine ; Hubbard-Lucey, Vanessa M ; Wherry, E John ; Ibrahim, Ramy ; Vonderheide, Robert H

The lancet oncology, 2021-01, Vol.22 (1), p.118-131 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy
Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy
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Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy

Vitale, Laura A. ; Thomas, Lawrence J. ; He, Li-Zhen ; O’Neill, Thomas ; Widger, Jenifer ; Crocker, Andrea ; Sundarapandiyan, Karuna ; Storey, James R. ; Forsberg, Eric M. ; Weidlick, Jeffrey ; Baronas, April R. ; Gergel, Lauren E. ; Boyer, James M. ; Sisson, Crystal ; Goldstein, Joel ; Marsh, Henry C. ; Keler, Tibor

Cancer Immunology, Immunotherapy, 2019-02, Vol.68 (2), p.233-245 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

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8
Reducing affinity as a strategy to boost immunomodulatory antibody agonism
Reducing affinity as a strategy to boost immunomodulatory antibody agonism
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Reducing affinity as a strategy to boost immunomodulatory antibody agonism

Yu, Xiaojie ; Orr, Christian M ; Chan, H T Claude ; James, Sonya ; Penfold, Christine A ; Kim, Jinny ; Inzhelevskaya, Tatyana ; Mockridge, C Ian ; Cox, Kerry L ; Essex, Jonathan W ; Tews, Ivo ; Glennie, Martin J ; Cragg, Mark S

Nature (London), 2023-02, Vol.614 (7948), p.539-547 [Periódico revisado por pares]

England: Nature Publishing Group

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9
Anti‐CD40 antibody 2C10 binds to a conformational epitope at the CD40‐CD154 interface that is conserved among primate species
Anti‐CD40 antibody 2C10 binds to a conformational epitope at the CD40‐CD154 interface that is conserved among primate species
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Anti‐CD40 antibody 2C10 binds to a conformational epitope at the CD40‐CD154 interface that is conserved among primate species

Michaels, Anthony J. ; Stoppato, Matteo ; Flores, Walter J. ; Reimann, Keith A. ; Engelman, Kathleen D.

American journal of transplantation, 2020-01, Vol.20 (1), p.298-305 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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10
Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40
Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40
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Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40

Foster, Aaron E. ; Mahendravada, Aruna ; Shinners, Nicholas P. ; Chang, Wei-Chun ; Crisostomo, Jeannette ; Lu, An ; Khalil, Mariam ; Morschl, Eva ; Shaw, Joanne L. ; Saha, Sunandan ; Duong, MyLinh T. ; Collinson-Pautz, Matthew R. ; Torres, David L. ; Rodriguez, Tania ; Pentcheva-Hoang, Tsvetelina ; Bayle, J. Henri ; Slawin, Kevin M. ; Spencer, David M.

Molecular therapy, 2017-09, Vol.25 (9), p.2176-2188 [Periódico revisado por pares]

United States: Elsevier Inc

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