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1
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Locasale, Jason W ; Cantley, Lewis C ; Vander Heiden, Matthew G ; Grassian, Alexandra R ; Melman, Tamar ; Lyssiotis, Costas A ; Mattaini, Katherine R ; Bass, Adam J ; Heffron, Gregory ; Metallo, Christian M ; Muranen, Taru ; Sharfi, Hadar ; Sasaki, Atsuo T ; Anastasiou, Dimitrios ; Mullarky, Edouard ; Vokes, Natalie I ; Sasaki, Mika ; Beroukhim, Rameen ; Stephanopoulos, Gregory ; Ligon, Azra H ; Meyerson, Matthew ; Richardson, Andrea L ; Chin, Lynda ; Wagner, Gerhard ; Asara, John M ; Brugge, Joan S

Nature genetics, 2011-09, Vol.43 (9), p.869-874 [Periódico revisado por pares]

New York, NY: Nature Publishing Group

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2
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
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Tumors as Organs: Complex Tissues that Interface with the Entire Organism

Egeblad, Mikala ; Nakasone, Elizabeth S. ; Werb, Zena

Developmental cell, 2010-06, Vol.18 (6), p.884-901 [Periódico revisado por pares]

Cambridge, MA: Elsevier Inc

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3
Transformation by the (R)―enantiomer of 2-hydroxyglutarate linked to EGLN activation
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Transformation by the (R)―enantiomer of 2-hydroxyglutarate linked to EGLN activation

KOIVUNEN, Peppi ; LEE, Sungwoo ; TRAVINS, Jeremy ; WEISS, Samuel ; LOOPER, Ryan ; LIGON, Keith L ; VERHAAK, Roel G. W ; HAI YAN ; KAELIN, William G ; DUNCAN, Christopher G ; LOPEZ, Giselle ; GANG LU ; RAMKISSOON, Shakti ; LOSMAN, Julie A ; JOENSUU, Paivi ; BERGMANN, Ulrich ; GROSS, Stefan

Nature (London), 2012-03, Vol.483 (7390), p.484-488 [Periódico revisado por pares]

London: Nature Publishing Group

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4
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation
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SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

BARBER, Matthew F ; MICHISHITA-KIOI, Eriko ; STRUHL, Kevin ; GARCIA, Benjamin A ; GOZANI, Or ; WEI LI ; CHUA, Katrin F ; YUANXIN XI ; TASSELLI, Luisa ; KIOI, Mitomu ; MOQTADERI, Zarmik ; TENNEN, Ruth I ; PAREDES, Silvana ; YOUNG, Nicolas L ; CHEN, Kaifu

Nature (London), 2012-07, Vol.487 (7405), p.114-118 [Periódico revisado por pares]

London: Nature Publishing Group

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5
Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways
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Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways

Pratheeshkumar, Poyil ; Son, Young-Ok ; Divya, Sasidharan Padmaja ; Roy, Ram Vinod ; Hitron, John Andrew ; Wang, Lei ; Kim, Donghern ; Dai, Jin ; Asha, Padmaja ; Zhang, Zhuo ; Wang, Yitao ; Shi, Xianglin

Toxicology and applied pharmacology, 2014-12, Vol.281 (2), p.230-241 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

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6
EMT and Stem Cell―Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells
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EMT and Stem Cell―Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells

TELLEZ, Carmen S ; JURI, Daniel E ; KIEU DO ; BERNAUER, Amanda M ; THOMAS, Cindy L ; DAMIANI, Leah A ; TESSEMA, Mathewos ; SHUGUANG LENG ; BELINSKY, Steven A

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8), p.3087-3097 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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7
A continuum model for tumour suppression
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A continuum model for tumour suppression

BERGER, Alice H ; KNUDSON, Alfred G ; PAOLO PANDOLFI, Pier

Nature (London), 2011-08, Vol.476 (7359), p.163-169 [Periódico revisado por pares]

London: Nature Publishing Group

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8
The transcriptional network for mesenchymal transformation of brain tumours
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The transcriptional network for mesenchymal transformation of brain tumours

Lasorella, Anna ; Lim, Wei Keat ; Carro, Maria Stella ; Anne, Sandrine L ; Alvarez, Mariano Javier ; Doetsch, Fiona ; Aldape, Ken ; Iavarone, Antonio ; Colman, Howard ; Zhao, Xudong ; Snyder, Evan Y ; Sulman, Erik P ; Califano, Andrea ; Bollo, Robert J

Nature (London), 2010-01, Vol.463 (7279), p.318-325 [Periódico revisado por pares]

London: Nature Publishing Group

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9
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

DENICOLA, Gina M ; KARRETH, Florian A ; SCRIMIERI, Francesca ; WINTER, Jordan M ; HRUBAN, Ralph H ; IACOBUZIO-DONAHUE, Christine ; KERN, Scott E ; BLAIR, Ian A ; TUVESON, David A ; HUMPTON, Timothy J ; GOPINATHAN, Aarthi ; CONG WEI ; FRESE, Kristopher ; MANGAL, Dipti ; YU, Kenneth H ; YEO, Charles J ; CALHOUN, Eric S

Nature (London), 2011-07, Vol.475 (7354), p.106-109 [Periódico revisado por pares]

London: Nature Publishing Group

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10
Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis
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Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis

HUANG, Emina H ; HYNES, Mark J ; TAO ZHANG ; GINESTIER, Christophe ; DONTU, Gabriela ; APPELMAN, Henry ; FIELDS, Jeremy Z ; WICHA, Max S ; BOMAN, Bruce M

Cancer research (Chicago, Ill.), 2009-04, Vol.69 (8), p.3382-3389 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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