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Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A
Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A
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Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A

Ozelo, MC ; Mahlangu, J ; Pasi, KJ ; Giermasz, A ; Leavitt, AD ; Laffan, M ; Symington, E ; Quon, D ; Wang, J-D ; Peerlinck, K ; Pipe, SW ; Madan, B ; Key, NS ; Pierce, GF ; O'Mahony, B ; Kaczmarek, R ; Henshaw, J ; Lawal, A ; Jayaram, K ; Huang, M ; Yang, X ; Wong, WY ; Kim, B

MASSACHUSETTS MEDICAL SOC 2022-03

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2
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

High, Katherine A ; Manno, Catherine S ; Pierce, Glenn F ; Arruda, Valder R ; Glader, Bertil ; Ragni, Margaret ; Rasko, John J E ; Ozelo, Margareth C ; Hoots, Keith ; Blatt, Philip ; Konkle, Barbara ; Dake, Michael ; Kaye, Robin ; Razavi, Mahmood ; Zajko, Albert ; Zehnder, James ; Rustagi, Pradip ; Nakai, Hiroyuki ; Chew, Amy ; Leonard, Debra ; Wright, J Fraser ; Lessard, Ruth R ; Sommer, Jürg M ; Tigges, Michael ; Sabatino, Denise ; Luk, Alvin ; Jiang, Haiyan ; Mingozzi, Federico ; Couto, Linda ; Ertl, Hildegund C ; Kay, Mark A

Nature medicine, 2006-03, Vol.12 (3), p.342-347 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
Genotypes, Phenotypes, and Whole Genome Sequence: Approaches from the MyLifeOurFuture Haemophilia Project
Genotypes, Phenotypes, and Whole Genome Sequence: Approaches from the MyLifeOurFuture Haemophilia Project
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Genotypes, Phenotypes, and Whole Genome Sequence: Approaches from the MyLifeOurFuture Haemophilia Project

Konkle, BA ; Johnsen, JM ; Wheeler, M ; Watson, C ; Skinner, M ; Pierce, GF

Haemophilia : the official journal of the World Federation of Hemophilia, 2018-05, Vol.24 (Suppl 6), p.87-94 [Periódico revisado por pares]

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4
Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice
Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice
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Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice

Scallan, Ciaran D. ; Jiang, Haiyan ; Liu, Tongyao ; Patarroyo-White, Susannah ; Sommer, Jurg M. ; Zhou, Shangzhen ; Couto, Linda B. ; Pierce, Glenn F.

Blood, 2006-03, Vol.107 (5), p.1810-1817 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Mutations on the External Surfaces of Adeno-Associated Virus Type 2 Capsids That Affect Transduction and Neutralization
Mutations on the External Surfaces of Adeno-Associated Virus Type 2 Capsids That Affect Transduction and Neutralization
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Mutations on the External Surfaces of Adeno-Associated Virus Type 2 Capsids That Affect Transduction and Neutralization

Lochrie, Michael A ; Tatsuno, Gwen P ; Christie, Brian ; McDonnell, Jennifer Wellman ; Zhou, Shangzhen ; Surosky, Richard ; Pierce, Glenn F ; Colosi, Peter

Journal of Virology, 2006-01, Vol.80 (2), p.821-834 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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6
Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs
Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs
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Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs

Jiang, Haiyan ; Lillicrap, David ; Patarroyo-White, Susannah ; Liu, Tongyao ; Qian, Xiaobing ; Scallan, Ciaran D. ; Powell, Sandra ; Keller, Tracey ; McMurray, Morag ; Labelle, Andrea ; Nagy, Dea ; Vargas, Joseph A. ; Zhou, Shangzhen ; Couto, Linda B. ; Pierce, Glenn F.

Blood, 2006-07, Vol.108 (1), p.107-115 [Periódico revisado por pares]

United States: Elsevier Inc

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7
Inflammation in Nonhealing Diabetic Wounds: The Space-Time Continuum Does Matter
Inflammation in Nonhealing Diabetic Wounds: The Space-Time Continuum Does Matter
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Inflammation in Nonhealing Diabetic Wounds: The Space-Time Continuum Does Matter

Pierce, Glenn F.

The American journal of pathology, 2001-08, Vol.159 (2), p.399-403 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Identification of factors that contribute to recombinant AAV2 particle aggregation and methods to prevent its occurrence during vector purification and formulation
Identification of factors that contribute to recombinant AAV2 particle aggregation and methods to prevent its occurrence during vector purification and formulation
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Identification of factors that contribute to recombinant AAV2 particle aggregation and methods to prevent its occurrence during vector purification and formulation

Wright, J Fraser ; Le, Tannie ; Prado, Joseph ; Bahr-Davidson, Jennifer ; Smith, Peter H ; Zhen, Zhu ; Sommer, Jurg M ; Pierce, Glenn F ; Qu, Guang

Molecular therapy, 2005-07, Vol.12 (1), p.171-178 [Periódico revisado por pares]

United States: Elsevier Limited

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9
AAV2-mediated gene delivery to monkey putamen: Evaluation of an infusion device and delivery parameters
AAV2-mediated gene delivery to monkey putamen: Evaluation of an infusion device and delivery parameters
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AAV2-mediated gene delivery to monkey putamen: Evaluation of an infusion device and delivery parameters

Sanftner, Laura M. ; Sommer, Jurg M. ; Suzuki, Brian M. ; Smith, Peter H. ; Vijay, Sharmila ; Vargas, Joseph A. ; Forsayeth, John R. ; Cunningham, Janet ; Bankiewicz, Krys S. ; Kao, Haihwa ; Bernal, Jan ; Pierce, Glenn F. ; Johnson, Kirk W.

Experimental neurology, 2005-08, Vol.194 (2), p.476-483 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

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10
Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered in Collagen Exhibits Safety, Biodistribution, and Immunogenicity Profiles Favorable for Clinical Use
Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered in Collagen Exhibits Safety, Biodistribution, and Immunogenicity Profiles Favorable for Clinical Use
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Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered in Collagen Exhibits Safety, Biodistribution, and Immunogenicity Profiles Favorable for Clinical Use

Gu, Dan-ling ; Nguyen, Thanh ; Gonzalez, Ana Maria ; Printz, Marie A ; Pierce, Glenn F ; Sosnowski, Barbara A ; Phillips, M Laurie ; Chandler, Lois A

Molecular therapy, 2004-05, Vol.9 (5), p.699-711 [Periódico revisado por pares]

United States: Elsevier Limited

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