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Material Type: Artigo
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The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer’s diseaseLonnemann, Niklas ; Hosseini, Shirin ; Marchetti, Carlo ; Skouras, Damaris B. ; Stefanoni, Davide ; D’Alessandro, Angelo ; Dinarello, Charles A. ; Korte, MartinProceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (50), p.32145-32154 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Comprehensive Review on Alzheimer's Disease: Causes and TreatmentBreijyeh, Zeinab ; Karaman, RafikMolecules (Basel, Switzerland), 2020-12, Vol.25 (24), p.5789 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Material Type: Artigo
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β-Amyloid accumulation in the human brain after one night of sleep deprivationShokri-Kojori, Ehsan ; Wang, Gene-Jack ; Wiers, Corinde E. ; Demiral, Sukru B. ; Guo, Min ; Kim, Sung Won ; Lindgren, Elsa ; Ramirez, Veronica ; Zehra, Amna ; Freeman, Clara ; Miller, Gregg ; Manza, Peter ; Srivastava, Tansha ; De Santi, Susan ; Tomasi, Dardo ; Benveniste, Helene ; Volkow, Nora D.Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (17), p.4483-4488 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's diseaseSalloway, Stephen ; Farlow, Martin ; McDade, Eric ; Clifford, David B ; Wang, Guoqiao ; Llibre-Guerra, Jorge J ; Hitchcock, Janice M ; Mills, Susan L ; Santacruz, Anna M ; Aschenbrenner, Andrew J ; Hassenstab, Jason ; Benzinger, Tammie L S ; Gordon, Brian A ; Fagan, Anne M ; Coalier, Kelley A ; Cruchaga, Carlos ; Goate, Alison A ; Perrin, Richard J ; Xiong, Chengjie ; Li, Yan ; Morris, John C ; Snider, B Joy ; Mummery, Catherine ; Surti, G Mustafa ; Hannequin, Didier ; Wallon, David ; Berman, Sarah B ; Lah, James J ; Jimenez-Velazquez, Ivonne Z ; Roberson, Erik D ; van Dyck, Christopher H ; Honig, Lawrence S ; Sánchez-Valle, Raquel ; Brooks, William S ; Gauthier, Serge ; Galasko, Douglas R ; Masters, Colin L ; Brosch, Jared R ; Hsiung, Ging-Yuek Robin ; Jayadev, Suman ; Formaglio, Maité ; Masellis, Mario ; Clarnette, Roger ; Pariente, Jérémie ; Dubois, Bruno ; Pasquier, Florence ; Jack, Jr, Clifford R ; Koeppe, Robert ; Snyder, Peter J ; Aisen, Paul S ; Thomas, Ronald G ; Berry, Scott M ; Wendelberger, Barbara A ; Andersen, Scott W ; Holdridge, Karen C ; Mintun, Mark A ; Yaari, Roy ; Sims, John R ; Baudler, Monika ; Delmar, Paul ; Doody, Rachelle S ; Fontoura, Paulo ; Giacobino, Caroline ; Kerchner, Geoffrey A ; Bateman, Randall JNature Medicine, 2021-07, Vol.27 (7), p.1187-1196 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer’s diseaseZhang, Xiuming ; Mormino, Elizabeth C. ; Sun, Nanbo ; Sperling, Reisa A. ; Sabuncu, Mert R. ; Yeo, B. T. ThomasProceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (42), p.E6535-E6544 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Mass spectrometry‐based methods for robust measurement of Alzheimer's disease biomarkers in biological fluidsKorecka, Magdalena ; Shaw, Leslie M.Journal of neurochemistry, 2021-10, Vol.159 (2), p.211-233 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysisWest, Tim ; Kirmess, Kristopher M ; Meyer, Matthew R ; Holubasch, Mary S ; Knapik, Stephanie S ; Hu, Yan ; Contois, John H ; Jackson, Erin N ; Harpstrite, Scott E ; Bateman, Randall J ; Holtzman, David M ; Verghese, Philip B ; Fogelman, Ilana ; Braunstein, Joel B ; Yarasheski, Kevin EMolecular neurodegeneration, 2021-05, Vol.16 (1), p.30-12, Article 30 [Periódico revisado por pares]England: BioMed CentralTexto completo disponível |
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Material Type: Artigo
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A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's diseaseBarthélemy, Nicolas R ; Li, Yan ; Joseph-Mathurin, Nelly ; Gordon, Brian A ; Hassenstab, Jason ; Benzinger, Tammie L S ; Buckles, Virginia ; Fagan, Anne M ; Perrin, Richard J ; Goate, Alison M ; Morris, John C ; Karch, Celeste M ; Xiong, Chengjie ; Allegri, Ricardo ; Mendez, Patricio Chrem ; Berman, Sarah B ; Ikeuchi, Takeshi ; Mori, Hiroshi ; Shimada, Hiroyuki ; Shoji, Mikio ; Suzuki, Kazushi ; Noble, James ; Farlow, Martin ; Chhatwal, Jasmeer ; Graff-Radford, Neill R ; Salloway, Stephen ; Schofield, Peter R ; Masters, Colin L ; Martins, Ralph N ; O'Connor, Antoinette ; Fox, Nick C ; Levin, Johannes ; Jucker, Mathias ; Gabelle, Audrey ; Lehmann, Sylvain ; Sato, Chihiro ; Bateman, Randall J ; McDade, EricNature Medicine, 2020-03, Vol.26 (3), p.398-407 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's DiseaseSalloway, Stephen ; Sperling, Reisa ; Fox, Nick C ; Blennow, Kaj ; Klunk, William ; Raskind, Murray ; Sabbagh, Marwan ; Honig, Lawrence S ; Porsteinsson, Anton P ; Ferris, Steven ; Reichert, Marcel ; Ketter, Nzeera ; Nejadnik, Bijan ; Guenzler, Volkmar ; Miloslavsky, Maja ; Wang, Daniel ; Lu, Yuan ; Lull, Julia ; Tudor, Iulia Cristina ; Liu, Enchi ; Grundman, Michael ; Yuen, Eric ; Black, Ronald ; Brashear, H. RobertThe New England journal of medicine, 2014-01, Vol.370 (4), p.322-333 [Periódico revisado por pares]Waltham, MA: Massachusetts Medical SocietyTexto completo disponível |
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Material Type: Artigo
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Differential diagnosis of Alzheimer’s disease using spectrochemical analysis of bloodParaskevaidi, Maria ; Morais, Camilo L. M. ; Lima, Kássio M. G. ; Snowden, Julie S. ; Saxon, Jennifer A. ; Richardson, Anna M. T. ; Jones, Matthew ; Mann, David M. A. ; Allsop, David ; Martin-Hirsch, Pierre L. ; Martin, Francis L.Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (38), p.E7929-E7938 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |