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11 |
Material Type: Artigo
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α‐Synuclein toxicity in yeast and human cells is caused by cell cycle re‐entry and autophagy degradation of ribonucleotide reductase 1Sampaio‐Marques, Belém ; Guedes, Ana ; Vasilevskiy, Igor ; Gonçalves, Susana ; Outeiro, Tiago F. ; Winderickx, Joris ; Burhans, William C. ; Ludovico, PaulaAging cell, 2019-08, Vol.18 (4), p.e12922-n/a [Periódico revisado por pares]England: John Wiley & Sons, IncTexto completo disponível |
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12 |
Material Type: Artigo
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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cellsHansen, Christian ; Angot, Elodie ; Bergström, Ann-Louise ; Steiner, Jennifer A ; Pieri, Laura ; Paul, Gesine ; Outeiro, Tiago F ; Melki, Ronald ; Kallunki, Pekka ; Fog, Karina ; Li, Jia-Yi ; Brundin, PatrikThe Journal of clinical investigation, 2011-02, Vol.121 (2), p.715-725 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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13 |
Material Type: Artigo
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The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type α-synucleinSun, Yunpeng ; Long, Houfang ; Xia, Wencheng ; Wang, Kun ; Zhang, Xia ; Sun, Bo ; Cao, Qin ; Zhang, Yaoyang ; Dai, Bin ; Li, Dan ; Liu, CongNature communications, 2021-10, Vol.12 (1), p.6252-6252, Article 6252 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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14 |
Material Type: Artigo
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The Brainstem Pathologies of Parkinson's Disease and Dementia with Lewy BodiesSeidel, Kay ; Mahlke, Josefine ; Siswanto, Sonny ; Krüger, Reijko ; Heinsen, Helmut ; Auburger, Georg ; Bouzrou, Mohamed ; Grinberg, Lea T. ; Wicht, Helmut ; Korf, Horst-Werner ; den Dunnen, Wilfred ; Rüb, UdoBrain pathology (Zurich, Switzerland), 2015-03, Vol.25 (2), p.121-135 [Periódico revisado por pares]Switzerland: Blackwell Publishing LtdTexto completo disponível |
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15 |
Material Type: Artigo
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Phenotypic manifestation of α-synuclein strains derived from Parkinson's disease and multiple system atrophy in human dopaminergic neuronsTanudjojo, Benedict ; Shaikh, Samiha S ; Fenyi, Alexis ; Bousset, Luc ; Agarwal, Devika ; Marsh, Jade ; Zois, Christos ; Heman-Ackah, Sabrina ; Fischer, Roman ; Sims, David ; Melki, Ronald ; Tofaris, George KNature communications, 2021-06, Vol.12 (1), p.3817-16, Article 3817 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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16 |
Material Type: Artigo
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Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviourFusco, Giuliana ; De Simone, Alfonso ; Gopinath, Tata ; Vostrikov, Vitaly ; Vendruscolo, Michele ; Dobson, Christopher M ; Veglia, GianluigiNature communications, 2014-05, Vol.5 (1), p.3827-3827, Article 3827 [Periódico revisado por pares]EnglandTexto completo disponível |
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17 |
Material Type: Artigo
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CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's diseaseBengoa-Vergniory, Nora ; Faggiani, Emilie ; Ramos-Gonzalez, Paula ; Kirkiz, Ecem ; Connor-Robson, Natalie ; Brown, Liam V ; Siddique, Ibrar ; Li, Zizheng ; Vingill, Siv ; Cioroch, Milena ; Cavaliere, Fabio ; Threlfell, Sarah ; Roberts, Bradley ; Schrader, Thomas ; Klärner, Frank-Gerrit ; Cragg, Stephanie ; Dehay, Benjamin ; Bitan, Gal ; Matute, Carlos ; Bezard, Erwan ; Wade-Martins, RichardNature communications, 2020-09, Vol.11 (1), p.4885-4885, Article 4885 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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18 |
Material Type: Artigo
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shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease modelZharikov, Alevtina D ; Cannon, Jason R ; Tapias, Victor ; Bai, Qing ; Horowitz, Max P ; Shah, Vipul ; El Ayadi, Amina ; Hastings, Teresa G ; Greenamyre, J Timothy ; Burton, Edward AThe Journal of clinical investigation, 2015-07, Vol.125 (7), p.2721-2735 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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19 |
Material Type: Artigo
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Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease modelsKarpinar, Damla Pinar ; Balija, Madhu Babu Gajula ; Kügler, Sebastian ; Opazo, Felipe ; Rezaei-Ghaleh, Nasrollah ; Wender, Nora ; Kim, Hai-Young ; Taschenberger, Grit ; Falkenburger, Björn H ; Heise, Henrike ; Kumar, Ashutosh ; Riedel, Dietmar ; Fichtner, Lars ; Voigt, Aaron ; Braus, Gerhard H ; Giller, Karin ; Becker, Stefan ; Herzig, Alf ; Baldus, Marc ; Jäckle, Herbert ; Eimer, Stefan ; Schulz, Jörg B ; Griesinger, Christian ; Zweckstetter, MarkusThe EMBO journal, 2009-10, Vol.28 (20), p.3256-3268 [Periódico revisado por pares]Chichester, UK: John Wiley & Sons, LtdTexto completo disponível |
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20 |
Material Type: Artigo
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Alpha‐synuclein aggregates activate calcium pump SERCA leading to calcium dysregulationBetzer, Cristine ; Lassen, Louise Berkhoudt ; Olsen, Anders ; Kofoed, Rikke Hahn ; Reimer, Lasse ; Gregersen, Emil ; Zheng, Jin ; Calì, Tito ; Gai, Wei‐Ping ; Chen, Tong ; Moeller, Arne ; Brini, Marisa ; Fu, Yuhong ; Halliday, Glenda ; Brudek, Tomasz ; Aznar, Susana ; Pakkenberg, Bente ; Andersen, Jens Peter ; Jensen, Poul HenningEMBO reports, 2018-05, Vol.19 (5), p.n/a [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |