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1
A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1
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A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1

Wang, Yingfei ; An, Ran ; Umanah, George K. ; Park, Hyejin ; Nambiar, Kalyani ; Eacker, Stephen M. ; Kim, BongWoo ; Bao, Lei ; Harraz, Maged M. ; Chang, Calvin ; Chen, Rong ; Wang, Jennifer E. ; Kam, Tae-In ; Jeong, Jun Seop ; Xie, Zhi ; Neifert, Stewart ; Qian, Jiang ; Andrabi, Shaida A. ; Blackshaw, Seth ; Zhu, Heng ; Song, Hongjun ; Ming, Guo-li ; Dawson, Valina L. ; Dawson, Ted M.

Science (American Association for the Advancement of Science), 2016-10, Vol.354 (6308), p.82-82 [Peer Reviewed Journal]

United States: American Association for the Advancement of Science

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2
D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)
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D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)

Merk, Melanie ; Zierow, Swen ; Leng, Lin ; Das, Rituparna ; Du, Xin ; Schulte, Wibke ; Fan, Juan ; Lue, Hongqi ; Chen, Yibang ; Xiong, Huabao ; Chagnon, Frederic ; Bernhagen, Jürgen ; Lolis, Elias ; Mor, Gil ; Lesur, Olivier ; Bucala, Richard

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (34), p.E577-E585 [Peer Reviewed Journal]

United States: National Academy of Sciences

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3
MIF and D-DT are potential disease severity modifiers in male MS subjects
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MIF and D-DT are potential disease severity modifiers in male MS subjects

Benedek, Gil ; Meza-Romero, Roberto ; Jordan, Kelley ; Zhang, Ying ; Nguyen, Ha ; Kent, Gail ; Li, Jia ; Siu, Edwin ; Frazer, Jenny ; Piecychna, Marta ; Du, Xin ; Sreih, Antoine ; Leng, Lin ; Wiedrick, Jack ; Caillier, Stacy J. ; Offner, Halina ; Oksenberg, Jorge R. ; Yadav, Vijayshree ; Bourdette, Dennis ; Bucala, Richard ; Vandenbark, Arthur A.

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (40), p.E8421-E8429 [Peer Reviewed Journal]

United States: National Academy of Sciences

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4
Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: EVIDENCE FOR PARTIAL ALLOSTERIC AGONISM IN COMPARISON WITH CXCL12 CHEMOKINE
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Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: EVIDENCE FOR PARTIAL ALLOSTERIC AGONISM IN COMPARISON WITH CXCL12 CHEMOKINE

Rajasekaran, Deepa ; Gröning, Sabine ; Schmitz, Corinna ; Zierow, Swen ; Drucker, Natalie ; Bakou, Maria ; Kohl, Kristian ; Mertens, André ; Lue, Hongqi ; Weber, Christian ; Xiao, Annie ; Luker, Gary ; Kapurniotu, Aphrodite ; Lolis, Elias ; Bernhagen, Jürgen

The Journal of biological chemistry, 2016-07, Vol.291 (30), p.15881-15895 [Peer Reviewed Journal]

United States: American Society for Biochemistry and Molecular Biology

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5
Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target
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Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target

Samuelsson, Bengt ; Morgenstern, Ralf ; Jakobsson, Per-Johan

Pharmacological reviews, 2007-09, Vol.59 (3), p.207-224 [Peer Reviewed Journal]

United States: American Society for Pharmacology and Experimental Therapeutics

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6
A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2
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A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2

Yang, Shouhui ; He, Peijun ; Wang, Jian ; Schetter, Aaron ; Tang, Wei ; Funamizu, Naotake ; Yanaga, Katsuhiko ; Uwagawa, Tadashi ; Satoskar, Abhay R ; Gaedcke, Jochen ; Bernhardt, Markus ; Ghadimi, B Michael ; Gaida, Matthias M ; Bergmann, Frank ; Werner, Jens ; Ried, Thomas ; Hanna, Nader ; Alexander, H Richard ; Hussain, S Perwez

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (13), p.3838-3850 [Peer Reviewed Journal]

United States

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7
Crystal structure of microsomal prostaglandin E₂ synthase provides insight into diversity in the MAPEG superfamily
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Crystal structure of microsomal prostaglandin E₂ synthase provides insight into diversity in the MAPEG superfamily

Sjögren, Tove ; Nord, Johan ; Ek, Margareta ; Johansson, Patrik ; Liu, Gang ; Geschwindner, Stefan

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.3806-3811 [Peer Reviewed Journal]

United States: National Academy of Sciences

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8
Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection
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Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection

Assunção-Miranda, Iranaia ; Amaral, Flavio A ; Bozza, Fernando A ; Fagundes, Caio T ; Sousa, Lirlandia P ; Souza, Danielle G ; Pacheco, Patrícia ; Barbosa-Lima, Giselle ; Gomes, Rachel N ; Bozza, Patrícia T ; Da Poian, Andrea T ; Teixeira, Mauro M ; Bozza, Marcelo T

The FASEB journal, 2010-01, Vol.24 (1), p.218-228 [Peer Reviewed Journal]

United States: The Federation of American Societies for Experimental Biology

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9
Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis
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Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis

Lee, James J. ; Natsuizaka, Mitsuteru ; Ohashi, Shinya ; Wong, Gabrielle S. ; Takaoka, Munenori ; Michaylira, Carmen Z. ; Budo, Daniela ; Tobias, John W. ; Kanai, Michiyuki ; Shirakawa, Yasuhiro ; Naomoto, Yoshio ; Klein-Szanto, Andres J.P. ; Haase, Volker H. ; Nakagawa, Hiroshi

Carcinogenesis (New York), 2010-03, Vol.31 (3), p.427-434 [Peer Reviewed Journal]

Oxford: Oxford University Press

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10
Macrophage migration inhibitory factor potentiates autoimmune-mediated neuroinflammation
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Macrophage migration inhibitory factor potentiates autoimmune-mediated neuroinflammation

Cox, Gina Mavrikis ; Kithcart, Aaron P ; Pitt, David ; Guan, Zhen ; Alexander, Jessica ; Williams, Jessica L ; Shawler, Todd ; Dagia, Nilesh M ; Popovich, Phillip G ; Satoskar, Abhay R ; Whitacre, Caroline C

The Journal of immunology (1950), 2013-08, Vol.191 (3), p.1043-1054 [Peer Reviewed Journal]

United States

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