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1 |
Material Type: Artigo
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The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studiesCopin, Richard ; Baum, Alina ; Wloga, Elzbieta ; Pascal, Kristen E. ; Giordano, Stephanie ; Fulton, Benjamin O. ; Zhou, Anbo ; Negron, Nicole ; Lanza, Kathryn ; Chan, Newton ; Coppola, Angel ; Chiu, Joyce ; Ni, Min ; Wei, Yi ; Atwal, Gurinder S. ; Hernandez, Annabel Romero ; Saotome, Kei ; Zhou, Yi ; Franklin, Matthew C. ; Hooper, Andrea T. ; McCarthy, Shane ; Hamon, Sara ; Hamilton, Jennifer D. ; Staples, Hilary M. ; Alfson, Kendra ; Carrion, Ricardo ; Ali, Shazia ; Norton, Thomas ; Somersan-Karakaya, Selin ; Sivapalasingam, Sumathi ; Herman, Gary A. ; Weinreich, David M. ; Lipsich, Leah ; Stahl, Neil ; Murphy, Andrew J. ; Yancopoulos, George D. ; Kyratsous, Christos A.Cell, 2021-07, Vol.184 (15), p.3949-3961.e11 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studiesSebti, S M ; Hamilton, A DOncogene, 2000-12, Vol.19 (56), p.6584-6593 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapiesHuang, B ; Cohen, J R ; Fernando, R I ; Hamilton, D H ; Litzinger, M T ; Hodge, J W ; Palena, CCell death & disease, 2013-06, Vol.4 (6), p.e682-e682 [Periódico revisado por pares]England: Springer Nature B.VTexto completo disponível |
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Material Type: Artigo
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“Gap guidance” of fibroblasts and epithelial cells by discontinuous edged surfacesHamilton, D.W. ; Brunette, D.M.Experimental cell research, 2005-10, Vol.309 (2), p.429-437 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A basophil-neuronal axis promotes itchWang, Fang ; Trier, Anna M. ; Li, Fengxian ; Kim, Seonyoung ; Chen, Zhen ; Chai, Jiani N. ; Mack, Madison R. ; Morrison, Stephanie A. ; Hamilton, Jennifer D. ; Baek, Jinok ; Yang, Ting-Lin B. ; Ver Heul, Aaron M. ; Xu, Amy Z. ; Xie, Zili ; Dong, Xintong ; Kubo, Masato ; Hu, Hongzhen ; Hsieh, Chyi-Song ; Dong, Xinzhong ; Liu, Qin ; Margolis, David J. ; Ardeleanu, Marius ; Miller, Mark J. ; Kim, Brian S.Cell, 2021-01, Vol.184 (2), p.422-440.e17 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Geranylgeranyltransferase I Inhibitors Target RalB To Inhibit Anchorage-Dependent Growth and Induce Apoptosis and RalA To Inhibit Anchorage-Independent GrowthFalsetti, Samuel C. ; Wang, De-an ; Peng, Hairuo ; Carrico, Dora ; Cox, Adrienne D. ; Der, Channing J. ; Hamilton, Andrew D. ; Sebti, Saïd M.Molecular and Cellular Biology, 2007-11, Vol.27 (22), p.8003-8014 [Periódico revisado por pares]United States: American Society for MicrobiologyTexto completo disponível |
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Material Type: Artigo
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Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenograftsSUN, J ; YIMIN QIAN ; HAMILTON, A. D ; SEBTI, S. MOncogene, 1998-03, Vol.16 (11), p.1467-1473 [Periódico revisado por pares]Basingstoke: Nature PublishingTexto completo disponível |
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Material Type: Artigo
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C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl HydroxylationEpstein, Andrew C.R. ; Gleadle, Jonathan M. ; McNeill, Luke A. ; Hewitson, Kirsty S. ; O'Rourke, John ; Mole, David R. ; Mukherji, Mridul ; Metzen, Eric ; Wilson, Michael I. ; Dhanda, Anu ; Tian, Ya-Min ; Masson, Norma ; Hamilton, Donald L. ; Jaakkola, Panu ; Barstead, Robert ; Hodgkin, Jonathan ; Maxwell, Patrick H. ; Pugh, Christopher W. ; Schofield, Christopher J. ; Ratcliffe, Peter J.Cell, 2001-10, Vol.107 (1), p.43-54 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptorsJIAZHI SUN ; WANG, De-An ; SEBTI, Saïd M ; JAIN, Rishi K ; CARIE, Adam ; PAQUETTE, Steve ; ENNIS, Eileen ; BLASKOVICH, Michelle A ; BALDINI, Laura ; COPPOLA, Domenico ; HAMILTON, Andrew DOncogene, 2005-07, Vol.24 (29), p.4701-4709 [Periódico revisado por pares]Basingstoke: Nature PublishingTexto completo disponível |
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Material Type: Artigo
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Disruption of Oncogenic K-Ras4B Processing and Signaling by a Potent Geranylgeranyltransferase I Inhibitor()Lerner, Edwina C. ; Qian, Yimin ; Hamilton, Andrew D. ; Sebti, Saïd M.The Journal of biological chemistry, 1995-11, Vol.270 (45), p.26770-26773 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |