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Frequency and amplitude control of cortical oscillations by phosphoinositide waves
Frequency and amplitude control of cortical oscillations by phosphoinositide waves
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Frequency and amplitude control of cortical oscillations by phosphoinositide waves

Xiong, Ding ; Xiao, Shengping ; Guo, Su ; Lin, Qingsong ; Nakatsu, Fubito ; Wu, Min

Nature chemical biology, 2016-03, Vol.12 (3), p.159-166 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition
PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition
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PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition

Spangle, Jennifer M. ; Von, Thanh ; Pavlick, Dean C. ; Khotimsky, Arina ; Zhao, Jean J. ; Roberts, Thomas M.

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (39), p.24427-24433 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases
Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases
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Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases

Li, Xinran ; Lau, Amy Y T ; Ng, Angel S N ; Aldehaiman, Abdullah ; Zhou, Yuan ; Ng, Patrick K S ; Arold, Stefan T ; Cheung, Lydia W T

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (37) [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Nuclear phosphoinositide signaling promotes YAP/TAZ-TEAD transcriptional activity in breast cancer
Nuclear phosphoinositide signaling promotes YAP/TAZ-TEAD transcriptional activity in breast cancer
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Nuclear phosphoinositide signaling promotes YAP/TAZ-TEAD transcriptional activity in breast cancer

Jung, Oisun ; Baek, Min-jeong ; Wooldrik, Colin ; Johnson, Keith R ; Fisher, Kurt W ; Lou, Jinchao ; Ricks, Tanei J ; Wen, Tianmu ; Best, Michael D ; Cryns, Vincent L ; Anderson, Richard A ; Choi, Suyong

The EMBO journal, 2024-05, Vol.43 (9), p.1740-1769 [Periódico revisado por pares]

London: Nature Publishing Group UK

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5
PI3Kβ links integrin activation and PI(3,4)P 2 production during invadopodial maturation
PI3Kβ links integrin activation and PI(3,4)P 2 production during invadopodial maturation
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PI3Kβ links integrin activation and PI(3,4)P 2 production during invadopodial maturation

Erami, Zahra ; Heitz, Samantha ; Bresnick, Anne R ; Backer, Jonathan M Weaver, Valerie Marie

Molecular biology of the cell, 2019-08, Vol.30 (18), p.2367-2376 [Periódico revisado por pares]

United States

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6
The Inhibitory Response to PI3K/AKT Pathway Inhibitors MK-2206 and Buparlisib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines
The Inhibitory Response to PI3K/AKT Pathway Inhibitors MK-2206 and Buparlisib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines
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The Inhibitory Response to PI3K/AKT Pathway Inhibitors MK-2206 and Buparlisib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines

Ma, Yixuan ; Sender, Sina ; Sekora, Anett ; Kong, Weibo ; Bauer, Peter ; Ameziane, Najim ; Al-Ali, Ruslan ; Krake, Susann ; Radefeldt, Mandy ; Weiss, Frank Ulrich ; Lerch, Markus M ; Parveen, Alisha ; Zechner, Dietmar ; Junghanss, Christian ; Murua Escobar, Hugo

International journal of molecular sciences, 2022-04, Vol.23 (8), p.4295 [Periódico revisado por pares]

Switzerland: MDPI AG

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7
Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer
Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer
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Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer

Sun, H ; Jiang, L ; Luo, X ; Jin, W ; He, Q ; An, J ; Lui, K ; Shi, J ; Rong, R ; Su, W ; Lucchesi, C ; Liu, Y ; Sheikh, M S ; Huang, Y

Oncogene, 2013-01, Vol.32 (2), p.234-241 [Periódico revisado por pares]

England: Nature Publishing Group

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8
PTEN Regulates PI(3,4)P 2 Signaling Downstream of Class I PI3K
PTEN Regulates PI(3,4)P 2 Signaling Downstream of Class I PI3K
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PTEN Regulates PI(3,4)P 2 Signaling Downstream of Class I PI3K

Malek, Mouhannad ; Kielkowska, Anna ; Chessa, Tamara ; Anderson, Karen E ; Barneda, David ; Pir, Pınar ; Nakanishi, Hiroki ; Eguchi, Satoshi ; Koizumi, Atsushi ; Sasaki, Junko ; Juvin, Véronique ; Kiselev, Vladimir Y ; Niewczas, Izabella ; Gray, Alexander ; Valayer, Alexandre ; Spensberger, Dominik ; Imbert, Marine ; Felisbino, Sergio ; Habuchi, Tomonori ; Beinke, Soren ; Cosulich, Sabina ; Le Novère, Nicolas ; Sasaki, Takehiko ; Clark, Jonathan ; Hawkins, Phillip T ; Stephens, Len R

Molecular cell, 2017-11, Vol.68 (3), p.566 [Periódico revisado por pares]

United States

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9
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors
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Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

Vasan, Neil ; Razavi, Pedram ; Johnson, Jared L ; Shao, Hong ; Shah, Hardik ; Antoine, Alesia ; Ladewig, Erik ; Gorelick, Alexander ; Lin, Ting-Yu ; Toska, Eneda ; Xu, Guotai ; Kazmi, Abiha ; Chang, Matthew T ; Taylor, Barry S ; Dickler, Maura N ; Jhaveri, Komal ; Chandarlapaty, Sarat ; Rabadan, Raul ; Reznik, Ed ; Smith, Melissa L ; Sebra, Robert ; Schimmoller, Frauke ; Wilson, Timothy R ; Friedman, Lori S ; Cantley, Lewis C ; Scaltriti, Maurizio ; Baselga, José

Science (American Association for the Advancement of Science), 2019-11, Vol.366 (6466), p.714-723 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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10
The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis
The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis
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The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis

Baxter, Amy A. ; Richter, Viviane ; Lay, Fung T. ; Poon, Ivan K. H. ; Adda, Christopher G. ; Veneer, Prem K. ; Phan, Thanh Kha ; Bleackley, Mark R. ; Anderson, Marilyn A. ; Kvansakul, Marc ; Hulett, Mark D.

Molecular and cellular biology, 2015-06, Vol.35 (11), p.1964-1978 [Periódico revisado por pares]

United States: Taylor & Francis

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